Item 1 of 2 (back to results) next teriflunomide A carboxamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > drug metabolite [CHEBI:49103] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   dihydroorotate dehydrogenase inhibitor [CHEBI:68542] (2)   teriflunomide [CHEBI:68540] (1)  protein kinase inhibitor [CHEBI:37699] (69)   tyrosine kinase inhibitor [CHEBI:38637] (38)   teriflunomide [CHEBI:68540] (1)  metabolite [CHEBI:25212] (2692)   drug metabolite [CHEBI:49103] (17)   teriflunomide [CHEBI:68540] (1)  aetiopathogenetic uses [CHEBI:52209] (178)   hepatotoxic agent [CHEBI:50908] (8)   teriflunomide [CHEBI:68540] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   anti-inflammatory drug [CHEBI:35472] (112)   non-steroidal anti-inflammatory drug [CHEBI:35475] (71)   teriflunomide [CHEBI:68540] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   teriflunomide [CHEBI:68540] (1)  p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   fluorine molecular entity [CHEBI:24062] (288)   organofluorine compound [CHEBI:37143] (275)   teriflunomide [CHEBI:68540] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   teriflunomide [CHEBI:68540] (1)  pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   amide [CHEBI:32988] (1863)   primary amide [CHEBI:33256] (1586)   carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  organonitrogen compound [CHEBI:35352] (6705)   cyanides [CHEBI:23424] (120)   nitrile [CHEBI:18379] (117)   teriflunomide [CHEBI:68540] (1)  carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   teriflunomide [CHEBI:68540] (1)  organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   cyanides [CHEBI:23424] (120)   nitrile [CHEBI:18379] (117)   teriflunomide [CHEBI:68540] (1)  carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   teriflunomide [CHEBI:68540] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carboxamide [CHEBI:37622] (1381)   teriflunomide [CHEBI:68540] (1)  organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   teriflunomide [CHEBI:68540] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   enol [CHEBI:33823] (52)   teriflunomide [CHEBI:68540] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   teriflunomide [CHEBI:68540] (1) ChEBI Compound Accession Identifier:   [CHEBI:68540] ChEBI Compound Description:   A carboxamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis. ChEBI Compound Identification Number:   68540 ChEBI InChI Value:   InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7- ChEBI InChIKey Value:   UTNUDOFZCWSZMS-YFHOEESVSA-N ChEBI Compound Name:   teriflunomide ChEBI SMILES Value:   C\\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)C(F)(F)F ChEBI Substance ID:   160645856 ChEBI URL:   ChEBI:68540 ChemSpider ID:   16737143 Ontomatica Chemical Accession Key (OnChAKey):   UTNUDOFZCWSZMS_YFHOEESVSA_N_000_000000 PubChem Compound ID:   54684141