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clonazepam
1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

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03. Biological Effects of Specific Chemicals: biophysical uses [CHEBI:52208] > membrane transport modulator [CHEBI:38632] > GABA modulator [CHEBI:50268]
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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > central nervous system drug [CHEBI:35470] > psychotropic drug [CHEBI:35471]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biophysical uses [CHEBI:52208] (136) 
 membrane transport modulator [CHEBI:38632] (122) 
 GABA modulator [CHEBI:50268] (9) 
 clonazepam [CHEBI:3756] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 central nervous system drug [CHEBI:35470] (217) 
 psychotropic drug [CHEBI:35471] (130) 
 tranquilizing drug [CHEBI:35473] (83) 
 anxiolytic drug [CHEBI:35474] (31) 
 clonazepam [CHEBI:3756] (1)
 central nervous system depressant [CHEBI:35488] (90) 
 anticonvulsant [CHEBI:35623] (39) 
 clonazepam [CHEBI:3756] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 polycyclic compound [CHEBI:33635] (4078) 
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 bicyclic compound [CHEBI:33636] (1511) 
 heterobicyclic compound [CHEBI:33672] (1315) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 heterobicyclic compound [CHEBI:33672] (1315) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 benzodiazepine [CHEBI:22720] (17) 
 1,4-benzodiazepinone [CHEBI:35500] (12) 
 clonazepam [CHEBI:3756] (1)
ChEBI Compound Accession Identifier:   [CHEBI:3756]
ChEBI Compound Description:   1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
ChEBI Compound Identification Number:   3756
ChEBI InChI Value:   InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
ChEBI InChIKey Value:   DGBIGWXXNGSACT-UHFFFAOYSA-N
ChEBI Compound Name:   clonazepam
ChEBI SMILES Value:   [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1
ChEBI Substance ID:   96079552
ChEBI URL:   ChEBI:3756
ChemSpider ID:   2700
Ontomatica Chemical Accession Key (OnChAKey):   DGBIGWXXNGSACT_UHFFFAOYSA_N_000_000000
PubChem Compound ID:   2802