Item 1 of 1 (back to results) dihydroergotamine Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > cardiovascular drug [CHEBI:35554] > vasoconstrictor agent [CHEBI:50514] > dihydroergotamine [CHEBI:4562] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   analgesic [CHEBI:35480] (114)   non-narcotic analgesic [CHEBI:35481] (56)   dihydroergotamine [CHEBI:4562] (1)  neurotransmitter agent [CHEBI:35942] (471)   adrenergic agent [CHEBI:37962] (143)   sympatholytic agent [CHEBI:66991] (10)   dihydroergotamine [CHEBI:4562] (1)  serotonergic drug [CHEBI:48278] (109)   serotonergic agonist [CHEBI:35941] (41)   dihydroergotamine [CHEBI:4562] (1)  dopaminergic agent [CHEBI:48560] (99)   dopamine agonist [CHEBI:51065] (26)   dihydroergotamine [CHEBI:4562] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   cardiovascular drug [CHEBI:35554] (162)   vasoconstrictor agent [CHEBI:50514] (29)   dihydroergotamine [CHEBI:4562] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   alkaloid [CHEBI:22315] (473)   indole alkaloid [CHEBI:38958] (144)   terpenoid indole alkaloid [CHEBI:65321] (57)   hemiterpenoid indole alkaloid [CHEBI:65322] (28)   ergot alkaloid [CHEBI:23943] (28)   dihydroergotamine [CHEBI:4562] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   alkaloid [CHEBI:22315] (473)   indole alkaloid [CHEBI:38958] (144)   terpenoid indole alkaloid [CHEBI:65321] (57)   hemiterpenoid indole alkaloid [CHEBI:65322] (28)   ergot alkaloid [CHEBI:23943] (28)   dihydroergotamine [CHEBI:4562] (1) ChEBI Compound Accession Identifier:   [CHEBI:4562] ChEBI Compound Description:   Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension. ChEBI Compound Identification Number:   4562 ChEBI InChI Value:   InChI=1S/C33H37N5O5/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39)/t21-,23-,25-,26+,27+,32-,33+/m1/s1 ChEBI InChIKey Value:   LUZRJRNZXALNLM-JGRZULCMSA-N ChEBI Compound Name:   dihydroergotamine ChEBI SMILES Value:   [H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@H](CN2C)C(=O)N[C@]1(C)O[C@]2(O)N([C@@H](Cc3ccccc3)C(=O)N3CCC[C@@]23[H])C1=O ChEBI Substance ID:   99313633 ChEBI URL:   ChEBI:4562 ChemSpider ID:   10091 Ontomatica Chemical Accession Key (OnChAKey):   LUZRJRNZXALNLM_JGRZULCMSA_N_000_000000 PubChem Compound ID:   10531