Item 2 of 170 (back to results) previous next aphidicolin A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication.

Current search: 07. Part of Biological Source of Chemical: unspecified structure [PO:0000004] × 03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   DNA polymerase inhibitor [CHEBI:38234] (7)   aphidicolin [CHEBI:2766] (1)  metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   aphidicolin [CHEBI:2766] (1)  antimicrobial agent [CHEBI:33281] (927)   antibiotic [CHEBI:22582] (193)   aphidicolin [CHEBI:2766] (1)  antiviral agent [CHEBI:22587] (216)   antiviral drug [CHEBI:36044] (50)   aphidicolin [CHEBI:2766] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   aphidicolin [CHEBI:2766] (1) 06. Name of Biological Source of Chemical  06. Name of Biological Source of Chemical  Fungi, Yeasts, Molds and Mildews (348)   Deuteromycotina (255)   Hyphomycetes (137)   Tolypocladium (9)   Tolypocladium inflatum (9) 07. Part of Biological Source of Chemical  07. Part of Biological Source of Chemical  unspecified structure [PO:0000004] (703) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   tetracyclic diterpenoid [CHEBI:52557] (25)   aphidicolin [CHEBI:2766] (1)  isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   tetracyclic diterpenoid [CHEBI:52557] (25)   aphidicolin [CHEBI:2766] (1) ChEBI Compound Accession Identifier:   [CHEBI:2766] ChEBI Compound Description:   A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. ChEBI Compound Identification Number:   2766 ChEBI InChI Value:   InChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1 ChEBI InChIKey Value:   NOFOAYPPHIUXJR-APNQCZIXSA-N ChEBI Compound Name:   aphidicolin ChEBI SMILES Value:   [H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]11CC[C@](O)(CO)[C@H](C2)C1 ChEBI Substance ID:   135610169 ChEBI URL:   ChEBI:2766 ChemSpider ID:   10280269 Ontomatica Chemical Accession Key (OnChAKey):   NOFOAYPPHIUXJR_APNQCZIXSA_N_000_000000 PubChem Compound ID:   457964