Item 2 of 3 (back to results) previous next regorafenib hydrate A hydrate that is the monohydrate form of anhydrous regorafenib. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy.

Current search: 03. Biological Effects of Specific Chemicals: aetiopathogenetic uses [CHEBI:52209] > hepatotoxic agent [CHEBI:50908] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > antineoplastic agent [CHEBI:35610] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   protein kinase inhibitor [CHEBI:37699] (69)   tyrosine kinase inhibitor [CHEBI:38637] (38)   regorafenib hydrate [CHEBI:68646] (1)  aetiopathogenetic uses [CHEBI:52209] (178)   hepatotoxic agent [CHEBI:50908] (8)   regorafenib hydrate [CHEBI:68646] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   regorafenib hydrate [CHEBI:68646] (1) 08. Chemical Category  08. Chemical Category  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   addition compound [CHEBI:35504] (113)   hydrate [CHEBI:35505] (111)   regorafenib hydrate [CHEBI:68646] (1) ChEBI Compound Accession Identifier:   [CHEBI:68646] ChEBI Compound Description:   A hydrate that is the monohydrate form of anhydrous regorafenib. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. ChEBI Compound Identification Number:   68646 ChEBI InChI Value:   "InChI=1S/C21H15ClF4N4O3.H2O/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H2" ChEBI InChIKey Value:   ZOPOQLDXFHBOIH-UHFFFAOYSA-N ChEBI Compound Name:   regorafenib hydrate ChEBI SMILES Value:   O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1 ChEBI Substance ID:   160645725 ChEBI URL:   ChEBI:68646 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   ZOPOQLDXFHBOIH_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   24768591