Item 12 of 13 (back to results) previous next felodipine The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Current search: 03. Biological Effects of Specific Chemicals: biophysical uses [CHEBI:52208] > membrane transport modulator [CHEBI:38632] > calcium channel modulator [CHEBI:38808] > calcium channel blocker [CHEBI:38215] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > cardiovascular drug [CHEBI:35554] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biophysical uses [CHEBI:52208] (136)   membrane transport modulator [CHEBI:38632] (122)   calcium channel modulator [CHEBI:38808] (32)   calcium channel blocker [CHEBI:38215] (24)   felodipine [CHEBI:585948] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antihypertensive agent [CHEBI:35674] (104)   felodipine [CHEBI:585948] (1)  cardiovascular drug [CHEBI:35554] (162)   vasodilator agent [CHEBI:35620] (65)   felodipine [CHEBI:585948] (1)  anti-arrhythmia drug [CHEBI:38070] (56)   felodipine [CHEBI:585948] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   chlorine molecular entity [CHEBI:23117] (884)   organochlorine compound [CHEBI:36683] (543)   felodipine [CHEBI:585948] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organochlorine compound [CHEBI:36683] (543)   felodipine [CHEBI:585948] (1)  pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organohalogen compound [CHEBI:36684] (976)   organochlorine compound [CHEBI:36683] (543)   felodipine [CHEBI:585948] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   monocyclic compound [CHEBI:33661] (2007)   heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  organonitrogen heterocyclic compound [CHEBI:38101] (3202)   pyridines [CHEBI:26421] (254)   dihydropyridine [CHEBI:50075] (10)   felodipine [CHEBI:585948] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organochlorine compound [CHEBI:36683] (543)   felodipine [CHEBI:585948] (1) ChEBI Compound Accession Identifier:   [CHEBI:585948] ChEBI Compound Description:   The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris. ChEBI Compound Identification Number:   585948 ChEBI InChI Value:   InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3 ChEBI InChIKey Value:   RZTAMFZIAATZDJ-UHFFFAOYSA-N ChEBI Compound Name:   felodipine ChEBI SMILES Value:   CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(Cl)c1Cl)C(=O)OC ChEBI Substance ID:   87351806 ChEBI URL:   ChEBI:585948 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   RZTAMFZIAATZDJ_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   3333