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difenoxin hydrochloride
The hydrochloride salt of difenoxin. It has similar actions and uses to diphenoxylate hydrochloride, being administered for the symptomatic treatment of acute and chronic diarrhoea. In an attempt to discourage abuse (at high doses, difenoxin acts like morphine), preparations usually contain subclinical amounts of atropine sulfate.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > gastrointestinal drug [CHEBI:55324]
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05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 gastrointestinal drug [CHEBI:55324] (24) 
 antidiarrhoeal drug [CHEBI:55323] (7) 
 difenoxin hydrochloride [CHEBI:59790] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 halogen molecular entity [CHEBI:24471] (1475) 
 chlorine molecular entity [CHEBI:23117] (884) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 difenoxin hydrochloride [CHEBI:59790] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 difenoxin hydrochloride [CHEBI:59790] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organic halide salt [CHEBI:51069] (386) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 difenoxin hydrochloride [CHEBI:59790] (1)
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 difenoxin hydrochloride [CHEBI:59790] (1)
 halide [CHEBI:37578] (1402) 
 halide salt [CHEBI:33958] (423) 
 chloride salt [CHEBI:23114] (326) 
 organic chloride salt [CHEBI:36094] (294) 
 hydrochloride [CHEBI:36807] (240) 
 difenoxin hydrochloride [CHEBI:59790] (1)
ChEBI Compound Accession Identifier  [CHEBI:59790]
ChEBI Compound Description  The hydrochloride salt of difenoxin. It has similar actions and uses to diphenoxylate hydrochloride, being administered for the symptomatic treatment of acute and chronic diarrhoea. In an attempt to discourage abuse (at high doses, difenoxin acts like morphine), preparations usually contain subclinical amounts of atropine sulfate.
ChEBI Compound Identification Number  59790
ChEBI InChI Value  "InChI=1S/C28H28N2O2.ClH/c29-22-28(24-12-6-2-7-13-24,25-14-8-3-9-15-25)18-21-30-19-16-27(17-20-30,26(31)32)23-10-4-1-5-11-23;/h1-15H,16-21H2,(H,31,32);1H"
ChEBI InChIKey Value  VMIZTXDGZPTKIK-UHFFFAOYSA-N
ChEBI Compound Name  difenoxin hydrochloride
ChEBI SMILES Value  [Cl-].OC(=O)C1(CC[NH+](CC1)CCC(C#N)(c1ccccc1)c1ccccc1)c1ccccc1
ChEBI Substance ID  99319564
ChEBI URL  ChEBI:59790
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  VMIZTXDGZPTKIK_UHFFFAOYSA_N_000_000000
PubChem Compound ID  37193