Item 18 of 66 (back to results) previous next esmolol A carboxylic ester that is methyl 3-(4-hydroxyphenyl)propanoate in which the hydrogen attached to the phenoic hydroxy group is substituted by a 2-hydroxy-3-(isopropylamino)propyl group. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] > neurotransmitter agent [CHEBI:35942] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > cardiovascular drug [CHEBI:35554] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   adrenergic agent [CHEBI:37962] (143)   adrenergic antagonist [CHEBI:37887] (75)   beta-adrenergic antagonist [CHEBI:35530] (33)   esmolol [CHEBI:4856] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   cardiovascular drug [CHEBI:35554] (162)   anti-arrhythmia drug [CHEBI:38070] (56)   esmolol [CHEBI:4856] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  amine [CHEBI:32952] (179)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  secondary amino compound [CHEBI:50995] (110)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  amine [CHEBI:32952] (179)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  secondary amino compound [CHEBI:50995] (110)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  ester [CHEBI:35701] (3370)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  organic amino compound [CHEBI:50047] (2472)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3)  amine [CHEBI:32952] (179)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  secondary amino compound [CHEBI:50995] (110)   secondary amine [CHEBI:32863] (27)   esmolol [CHEBI:4856] (3)  organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   organic molecule [CHEBI:72695] (11399)   organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   esmolol [CHEBI:4856] (3)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   amino alcohol [CHEBI:22478] (250)   ethanolamines [CHEBI:23981] (167)   esmolol [CHEBI:4856] (3) ChEBI Compound Accession Identifier:   [CHEBI:4856] ChEBI Compound Description:   A carboxylic ester that is methyl 3-(4-hydroxyphenyl)propanoate in which the hydrogen attached to the phenoic hydroxy group is substituted by a 2-hydroxy-3-(isopropylamino)propyl group. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. ChEBI Compound Identification Number:   4856 ChEBI InChI Value:   InChI=1S/C16H25NO4/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3 ChEBI InChIKey Value:   AQNDDEOPVVGCPG-UHFFFAOYSA-N ChEBI Compound Name:   esmolol ChEBI SMILES Value:   COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1 ChEBI Substance ID:   99313645 ChEBI URL:   ChEBI:4856 ChemSpider ID:   53916 Ontomatica Chemical Accession Key (OnChAKey):   AQNDDEOPVVGCPG_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   59768