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12-methyl-5-dehydrohorminone
An abietane diterpenoid that is 5-dehydrohorminone in which the hydroxy group at position 12 is replaced by a methoxy group. Isolated from the roots of Salvia multicaulis, it exhibits antitubercular activity.


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06. Name of Biological Source of Chemical: Plantae > Magnoliophyta > Magnoliopsida > Lamiales
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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 antimicrobial agent [CHEBI:33281] (927) 
 antibacterial agent [CHEBI:33282] (317) 
 antibacterial drug [CHEBI:36047] (177) 
 antimycobacterial drug [CHEBI:64912] (46) 
 antitubercular agent [CHEBI:33231] (29) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
06. Name of Biological Source of Chemical 
06. Name of Biological Source of Chemical
 Plantae (1926) 
 Magnoliophyta (1872) 
 Magnoliopsida (1649) 
 Lamiales (196) 
 Lamiaceae (156) 
 Salvia (22) 
 Salvia multicaulis (6)
07. Part of Biological Source of Chemical 
07. Part of Biological Source of Chemical
 plant structure [PO:0009011] (1497) 
 multi-tissue plant structure [PO:0025496] (1114) 
 plant organ [PO:0009008] (970) 
 plant axis [PO:0025004] (691) 
 root [PO:0009005] (486)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 enol ether [CHEBI:47985] (17) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 enol ether [CHEBI:47985] (17) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 lipid [CHEBI:18059] (3532) 
 isoprenoid [CHEBI:24913] (1402) 
 terpenoid [CHEBI:26873] (1099) 
 diterpenoid [CHEBI:23849] (265) 
 abietane diterpenoid [CHEBI:36762] (16) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 isoprenoid [CHEBI:24913] (1402) 
 terpenoid [CHEBI:26873] (1099) 
 diterpenoid [CHEBI:23849] (265) 
 abietane diterpenoid [CHEBI:36762] (16) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 ether [CHEBI:25698] (876) 
 enol ether [CHEBI:47985] (17) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 organic molecule [CHEBI:72695] (11399) 
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 cyclic ketone [CHEBI:3992] (644) 
 quinone [CHEBI:36141] (209) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 12-methyl-5-dehydrohorminone [CHEBI:66364] (1)
ChEBI Compound Accession Identifier  [CHEBI:66364]
ChEBI Compound Description  An abietane diterpenoid that is 5-dehydrohorminone in which the hydroxy group at position 12 is replaced by a methoxy group. Isolated from the roots of Salvia multicaulis, it exhibits antitubercular activity.
ChEBI Compound Identification Number  66364
ChEBI InChI Value  InChI=1S/C21H28O4/c1-11(2)14-17(23)15-12(22)10-13-20(3,4)8-7-9-21(13,5)16(15)18(24)19(14)25-6/h10-12,22H,7-9H2,1-6H3/t12-,21+/m1/s1
ChEBI InChIKey Value  RUONQJYGQKYSSL-GTJPDFRWSA-N
ChEBI Compound Name  12-methyl-5-dehydrohorminone
ChEBI SMILES Value  COC1=C(C(C)C)C(=O)C2=C(C1=O)[C@@]1(C)CCCC(C)(C)C1=C[C@H]2O
ChEBI Substance ID  160709911
ChEBI URL  ChEBI:66364
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  RUONQJYGQKYSSL_GTJPDFRWSA_N_000_000000
PubChem Compound ID  467786