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WR-1065
An alkanethiol that is the N-3-aminopropyl derivative of cysteamine. Used as the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212]
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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > protective agent [CHEBI:50267] > radiation protective agent [CHEBI:66987]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 drug metabolite [CHEBI:49103] (17) 
 WR-1065 [CHEBI:72583] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 protective agent [CHEBI:50267] (74) 
 radiation protective agent [CHEBI:66987] (6) 
 WR-1065 [CHEBI:72583] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 organic amino compound [CHEBI:50047] (2472) 
 diamine [CHEBI:23666] (39) 
 WR-1065 [CHEBI:72583] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 sulfur molecular entity [CHEBI:26835] (1541) 
 organosulfur compound [CHEBI:33261] (1005) 
 thiol [CHEBI:29256] (31) 
 alkanethiol [CHEBI:47908] (7) 
 WR-1065 [CHEBI:72583] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 thiol [CHEBI:29256] (31) 
 alkanethiol [CHEBI:47908] (7) 
 WR-1065 [CHEBI:72583] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organonitrogen compound [CHEBI:35352] (6705) 
 organic amino compound [CHEBI:50047] (2472) 
 diamine [CHEBI:23666] (39) 
 WR-1065 [CHEBI:72583] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 thiol [CHEBI:29256] (31) 
 alkanethiol [CHEBI:47908] (7) 
 WR-1065 [CHEBI:72583] (1)
 organic amino compound [CHEBI:50047] (2472) 
 diamine [CHEBI:23666] (39) 
 WR-1065 [CHEBI:72583] (1)
09. Chemical Capabilities 
09. Chemical Capabilities
 antioxidant [CHEBI:22586] (199) 
 WR-1065 [CHEBI:72583] (1)
ChEBI Compound Accession Identifier  [CHEBI:72583]
ChEBI Compound Description  An alkanethiol that is the N-3-aminopropyl derivative of cysteamine. Used as the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy.
ChEBI Compound Identification Number  72583
ChEBI InChI Value  InChI=1S/C5H14N2S/c6-2-1-3-7-4-5-8/h7-8H,1-6H2
ChEBI InChIKey Value  YHPLKWQJMAYFCN-UHFFFAOYSA-N
ChEBI Compound Name  WR-1065
ChEBI SMILES Value  NCCCNCCS
ChEBI Substance ID  160962742
ChEBI URL  ChEBI:72583
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  YHPLKWQJMAYFCN_UHFFFAOYSA_N_000_000000
PubChem Compound ID  104807