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pravastatin sodium
An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.


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03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > hydroxymethylglutaryl-CoA reductase inhibitor [CHEBI:35664]
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05. Industrial Uses: pharmaceutical [CHEBI:52217]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 hydroxymethylglutaryl-CoA reductase inhibitor [CHEBI:35664] (10) 
 pravastatin sodium [CHEBI:8361] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antilipemic drug [CHEBI:35679] (30) 
 anticholesteremic drug [CHEBI:35821] (15) 
 pravastatin sodium [CHEBI:8361] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 alkali metal molecular entity [CHEBI:33296] (279) 
 sodium molecular entity [CHEBI:26712] (216) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 pravastatin sodium [CHEBI:8361] (1)
 alkali metal salt [CHEBI:35479] (248) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 pravastatin sodium [CHEBI:8361] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 organic sodium salt [CHEBI:38700] (187) 
 pravastatin sodium [CHEBI:8361] (1)
 alkali metal salt [CHEBI:35479] (248) 
 sodium salt [CHEBI:26714] (213) 
 organic sodium salt [CHEBI:38700] (187) 
 pravastatin sodium [CHEBI:8361] (1)
ChEBI Compound Accession Identifier  [CHEBI:8361]
ChEBI Compound Description  An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.
ChEBI Compound Identification Number  8361
ChEBI InChI Value  "InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1"
ChEBI InChIKey Value  VWBQYTRBTXKKOG-IYNICTALSA-M
ChEBI Compound Name  pravastatin sodium
ChEBI SMILES Value  [Na+].[H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)OC(=O)[C@@H](C)CC
ChEBI Substance ID  135610194
ChEBI URL  ChEBI:8361
ChemSpider ID  49400
Ontomatica Chemical Accession Key (OnChAKey)  VWBQYTRBTXKKOG_IYNICTALSA_M_000_000000
PubChem Compound ID  16759173