Item 21 of 2769 (back to results) previous next amifostine A thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Current search: 08. Chemical Category: main group molecular entity [CHEBI:33579] > p-block molecular entity [CHEBI:33675] > pnictogen molecular entity [CHEBI:33302] > phosphorus molecular entity [CHEBI:26082] × Select any link to see items in a related category. more general categories    information about this item 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   prodrug [CHEBI:50266] (88)   amifostine [CHEBI:2636] (1)  protective agent [CHEBI:50267] (74)   radiation protective agent [CHEBI:66987] (6)   amifostine [CHEBI:2636] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   pnictogen molecular entity [CHEBI:33302] (10027)   phosphorus molecular entity [CHEBI:26082] (2769)   organophosphorus compound [CHEBI:25710] (1528)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  organothiophosphorus compound [CHEBI:25716] (53)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  phosphorus oxoacids and derivatives [CHEBI:36360] (2691)   phosphorus oxoacid derivative [CHEBI:36359] (2628)   phosphoric acid derivative [CHEBI:26079] (2611)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  phosphate [CHEBI:26020] (1522)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  thiophosphate [CHEBI:37511] (53)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  phosphoric ester [CHEBI:37734] (1466)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   diamine [CHEBI:23666] (39)   amifostine [CHEBI:2636] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   sulfur molecular entity [CHEBI:26835] (1541)   organothiophosphorus compound [CHEBI:25716] (53)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organophosphorus compound [CHEBI:25710] (1528)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  organothiophosphorus compound [CHEBI:25716] (53)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  organonitrogen compound [CHEBI:35352] (6705)   organic amino compound [CHEBI:50047] (2472)   diamine [CHEBI:23666] (39)   amifostine [CHEBI:2636] (1)  ester [CHEBI:35701] (3370)   phosphoric ester [CHEBI:37734] (1466)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  organic amino compound [CHEBI:50047] (2472)   diamine [CHEBI:23666] (39)   amifostine [CHEBI:2636] (1)  polyatomic entity [CHEBI:36357] (18777)   heteroatomic molecular entity [CHEBI:37577] (13672)   oxoacid derivative [CHEBI:33241] (3254)   phosphorus oxoacid derivative [CHEBI:36359] (2628)   phosphoric acid derivative [CHEBI:26079] (2611)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  phosphate [CHEBI:26020] (1522)   organic phosphate [CHEBI:25703] (1511)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  thiophosphate [CHEBI:37511] (53)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1)  phosphoric ester [CHEBI:37734] (1466)   organic thiophosphate [CHEBI:37512] (53)   amifostine [CHEBI:2636] (1) 09. Chemical Capabilities  09. Chemical Capabilities  antioxidant [CHEBI:22586] (199)   amifostine [CHEBI:2636] (1) ChEBI Compound Accession Identifier:   [CHEBI:2636] ChEBI Compound Description:   A thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. ChEBI Compound Identification Number:   2636 ChEBI InChI Value:   InChI=1S/C5H15N2O3PS/c6-2-1-3-7-4-5-12-11(8,9)10/h7H,1-6H2,(H2,8,9,10) ChEBI InChIKey Value:   JKOQGQFVAUAYPM-UHFFFAOYSA-N ChEBI Compound Name:   amifostine ChEBI SMILES Value:   NCCCNCCSP(O)(O)=O ChEBI Substance ID:   50139273 ChEBI URL:   ChEBI:2636 ChemSpider ID:   2056 Ontomatica Chemical Accession Key (OnChAKey):   JKOQGQFVAUAYPM_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   2141