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cyproheptadine hydrochloride sesquihydrate
The sesquihydrate of cyproheptadine hydrochloride. Note that the drug named cyproheptadine hydrochloride generally refers to cyproheptadine hydrochloride sesquihydrate. A sedating antihistamine with antimuscarinic and calcium-channel blocking actions, it is used for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > gastrointestinal drug [CHEBI:55324]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 neurotransmitter agent [CHEBI:35942] (471) 
 histaminergic drug [CHEBI:37957] (94) 
 histamine antagonist [CHEBI:37956] (87) 
 H1-receptor antagonist [CHEBI:37955] (57) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
 serotonergic drug [CHEBI:48278] (109) 
 serotonergic antagonist [CHEBI:48279] (52) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 dermatologic drug [CHEBI:50177] (49) 
 antipruritic drug [CHEBI:59683] (18) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
 anti-allergic agent [CHEBI:50857] (51) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
 gastrointestinal drug [CHEBI:55324] (24) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 addition compound [CHEBI:35504] (113) 
 hydrate [CHEBI:35505] (111) 
 cyproheptadine hydrochloride sesquihydrate [CHEBI:650917] (1)
ChEBI Compound Accession Identifier  [CHEBI:650917]
ChEBI Compound Description  The sesquihydrate of cyproheptadine hydrochloride. Note that the drug named cyproheptadine hydrochloride generally refers to cyproheptadine hydrochloride sesquihydrate. A sedating antihistamine with antimuscarinic and calcium-channel blocking actions, it is used for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
ChEBI Compound Identification Number  650917
ChEBI InChI Value  "InChI=1S/2C21H21N.2ClH.3H2O/c2*1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;;;;;/h2*2-11H,12-15H2,1H3;2*1H;3*1H2"
ChEBI InChIKey Value  ZEAUHIZSRUAMQG-UHFFFAOYSA-N
ChEBI Compound Name  cyproheptadine hydrochloride sesquihydrate
ChEBI SMILES Value  O.O.O.Cl.Cl.CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12.CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
ChEBI Substance ID  92737750
ChEBI URL  ChEBI:650917
ChemSpider ID  10128528
Ontomatica Chemical Accession Key (OnChAKey)  ZEAUHIZSRUAMQG_UHFFFAOYSA_N_000_000000
PubChem Compound ID  11954233