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anolignan B
A lignan that consists of buta-1,3-diene substituted by 4-hydroxybenzyl groups at positions 2 and 3. It is isolated from the ground stems of Anogeissus acuminata and exhibits anti-HIV activity by inhibiting HIV-1 reverse transcriptase enzyme.


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06. Name of Biological Source of Chemical: Plantae > Magnoliophyta
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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 anolignan B [CHEBI:65411] (1)
 antimicrobial agent [CHEBI:33281] (927) 
 antiviral agent [CHEBI:22587] (216) 
 anti-HIV agent [CHEBI:64946] (126) 
 anti-HIV-1 agent [CHEBI:64947] (79) 
 HIV-1 reverse transcriptase inhibitor [CHEBI:53756] (30) 
 anolignan B [CHEBI:65411] (1)
06. Name of Biological Source of Chemical 
06. Name of Biological Source of Chemical
 Plantae (1926) 
 Magnoliophyta (1872) 
 Magnoliopsida (1649) 
 Myrtales (33) 
 Combretaceae (25) 
 Anogeissus (2) 
 Anogeissus acuminata (2)
07. Part of Biological Source of Chemical 
07. Part of Biological Source of Chemical
 plant structure [PO:0009011] (1497) 
 multi-tissue plant structure [PO:0025496] (1114) 
 plant organ [PO:0009008] (970) 
 plant axis [PO:0025004] (691) 
 shoot axis [PO:0025029] (271) 
 stem [PO:0009047] (170)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenylpropanoid [CHEBI:26004] (374) 
 lignan [CHEBI:25036] (34) 
 anolignan B [CHEBI:65411] (1)
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 aromatic compound [CHEBI:33655] (3799) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenylpropanoid [CHEBI:26004] (374) 
 lignan [CHEBI:25036] (34) 
 anolignan B [CHEBI:65411] (1)
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenylpropanoid [CHEBI:26004] (374) 
 lignan [CHEBI:25036] (34) 
 anolignan B [CHEBI:65411] (1)
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenylpropanoid [CHEBI:26004] (374) 
 lignan [CHEBI:25036] (34) 
 anolignan B [CHEBI:65411] (1)
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 anolignan B [CHEBI:65411] (1)
ChEBI Compound Accession Identifier  [CHEBI:65411]
ChEBI Compound Description  A lignan that consists of buta-1,3-diene substituted by 4-hydroxybenzyl groups at positions 2 and 3. It is isolated from the ground stems of Anogeissus acuminata and exhibits anti-HIV activity by inhibiting HIV-1 reverse transcriptase enzyme.
ChEBI Compound Identification Number  65411
ChEBI InChI Value  InChI=1S/C18H18O2/c1-13(11-15-3-7-17(19)8-4-15)14(2)12-16-5-9-18(20)10-6-16/h3-10,19-20H,1-2,11-12H2
ChEBI InChIKey Value  VVKZAZVVUAFFGF-UHFFFAOYSA-N
ChEBI Compound Name  anolignan B
ChEBI SMILES Value  Oc1ccc(CC(=C)C(=C)Cc2ccc(O)cc2)cc1
ChEBI Substance ID  160645053
ChEBI URL  ChEBI:65411
ChemSpider ID  65322
Ontomatica Chemical Accession Key (OnChAKey)  VVKZAZVVUAFFGF_UHFFFAOYSA_N_000_000000
PubChem Compound ID  72388