Item 28 of 60 (back to results) previous next paclitaxel A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark.

Current search: 03. Biological Effects of Specific Chemicals: pharmacological uses [CHEBI:52210] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > antineoplastic agent [CHEBI:35610] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   paclitaxel [CHEBI:45863] (1)  pharmacological uses [CHEBI:52210] (736)   tubulin modulator [CHEBI:60832] (12)   microtubule-stabilising agent [CHEBI:61950] (3)   paclitaxel [CHEBI:45863] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antineoplastic agent [CHEBI:35610] (760)   paclitaxel [CHEBI:45863] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   taxane diterpenoid [CHEBI:50367] (11)   paclitaxel [CHEBI:45863] (1)  tetracyclic diterpenoid [CHEBI:52557] (25)   paclitaxel [CHEBI:45863] (1)  isoprenoid [CHEBI:24913] (1402)   terpenoid [CHEBI:26873] (1099)   diterpenoid [CHEBI:23849] (265)   taxane diterpenoid [CHEBI:50367] (11)   paclitaxel [CHEBI:45863] (1)  tetracyclic diterpenoid [CHEBI:52557] (25)   paclitaxel [CHEBI:45863] (1) ChEBI Compound Accession Identifier:   [CHEBI:45863] ChEBI Compound Description:   A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark. ChEBI Compound Identification Number:   45863 ChEBI InChI Value:   InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1 ChEBI InChIKey Value:   RCINICONZNJXQF-MZXODVADSA-N ChEBI Compound Name:   paclitaxel ChEBI SMILES Value:   [H][C@]12[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]1(C)[C@@H](O)C[C@H]1OC[C@@]21OC(C)=O)C3(C)C ChEBI Substance ID:   26697100 ChEBI URL:   ChEBI:45863 ChemSpider ID:   10368587 Ontomatica Chemical Accession Key (OnChAKey):   RCINICONZNJXQF_MZXODVADSA_N_000_000000 PubChem Compound ID:   36314