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auranofin
An S-glycosyl compound consisting of 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis.


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08. Chemical Category: transition element molecular entity [CHEBI:33497]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 enzyme inhibitor [CHEBI:23924] (825) 
 thioredoxin reductase inhibitor [CHEBI:64670] (1) 
 auranofin [CHEBI:2922] (1)
 immunomodulator [CHEBI:50846] (61) 
 immunosuppressive agent [CHEBI:35705] (43) 
 auranofin [CHEBI:2922] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antirheumatic drug [CHEBI:35842] (22) 
 auranofin [CHEBI:2922] (1)
08. Chemical Category 
08. Chemical Category
 transition element molecular entity [CHEBI:33497] (536) 
 d-block molecular entity [CHEBI:33676] (500) 
 copper group molecular entity [CHEBI:33745] (56) 
 gold molecular entity [CHEBI:33969] (22) 
 gold coordination entity [CHEBI:33971] (18) 
 auranofin [CHEBI:2922] (1)
 transition element coordination entity [CHEBI:33861] (358) 
 gold coordination entity [CHEBI:33971] (18) 
 auranofin [CHEBI:2922] (1)
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 glycosyl compound [CHEBI:63161] (1006) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 carbohydrate derivative [CHEBI:63299] (2582) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 sulfur molecular entity [CHEBI:26835] (1541) 
 organosulfur compound [CHEBI:33261] (1005) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 organooxygen compound [CHEBI:36963] (11352) 
 glycosyl compound [CHEBI:63161] (1006) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 carbohydrate derivative [CHEBI:63299] (2582) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organosulfur compound [CHEBI:33261] (1005) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 organooxygen compound [CHEBI:36963] (11352) 
 glycosyl compound [CHEBI:63161] (1006) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 carbohydrate derivative [CHEBI:63299] (2582) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 thiosugar [CHEBI:73754] (38) 
 S-glycosyl compound [CHEBI:35275] (37) 
 auranofin [CHEBI:2922] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 coordination entity [CHEBI:33240] (498) 
 transition element coordination entity [CHEBI:33861] (358) 
 gold coordination entity [CHEBI:33971] (18) 
 auranofin [CHEBI:2922] (1)
ChEBI Compound Accession Identifier  [CHEBI:2922]
ChEBI Compound Description  An S-glycosyl compound consisting of 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis.
ChEBI Compound Identification Number  2922
ChEBI InChI Value  "InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1"
ChEBI InChIKey Value  AUJRCFUBUPVWSZ-XTZHGVARSA-M
ChEBI Compound Name  auranofin
ChEBI SMILES Value  CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
ChEBI Substance ID  87351881
ChEBI URL  ChEBI:2922
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  AUJRCFUBUPVWSZ_XTZHGVARSA_M_000_000000
PubChem Compound ID  70788951