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cilofungin
A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycotic agent against Candida albicans.


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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antifungal agent [CHEBI:35718]
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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 antimicrobial agent [CHEBI:33281] (927) 
 antifungal agent [CHEBI:35718] (130) 
 cilofungin [CHEBI:315019] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antiinfective agent [CHEBI:35441] (82) 
 cilofungin [CHEBI:315019] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 p-block molecular entity [CHEBI:33675] (25343) 
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 amide [CHEBI:32988] (1863) 
 primary amide [CHEBI:33256] (1586) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 lipid [CHEBI:18059] (3532) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 heteroorganic entity [CHEBI:33285] (15197) 
 organonitrogen compound [CHEBI:35352] (6705) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carboxamide [CHEBI:37622] (1381) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
 organic amino compound [CHEBI:50047] (2472) 
 peptide [CHEBI:16670] (730) 
 lipopeptide [CHEBI:46895] (60) 
 echinocandin [CHEBI:57248] (4) 
 cilofungin [CHEBI:315019] (1)
ChEBI Compound Accession Identifier  [CHEBI:315019]
ChEBI Compound Description  A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycotic agent against Candida albicans.
ChEBI Compound Identification Number  315019
ChEBI InChI Value  InChI=1S/C49H71N7O17/c1-5-6-7-8-9-10-19-73-31-17-13-28(14-18-31)42(65)50-32-21-34(61)45(68)54-47(70)38-39(62)24(2)22-56(38)49(72)36(26(4)58)52-46(69)37(41(64)40(63)27-11-15-29(59)16-12-27)53-44(67)33-20-30(60)23-55(33)48(71)35(25(3)57)51-43(32)66/h11-18,24-26,30,32-41,45,57-64,68H,5-10,19-23H2,1-4H3,(H,50,65)(H,51,66)(H,52,69)(H,53,67)(H,54,70)/t24-,25+,26+,30+,32-,33-,34+,35-,36-,37-,38-,39-,40-,41-,45+/m0/s1
ChEBI InChIKey Value  ZKZKCEAHVFVZDJ-MTUMARHDSA-N
ChEBI Compound Name  cilofungin
ChEBI SMILES Value  CCCCCCCCOc1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)cc1)[C@@H](C)O
ChEBI Substance ID  85507136
ChEBI URL  ChEBI:315019
ChemSpider ID  NS
Ontomatica Chemical Accession Key (OnChAKey)  ZKZKCEAHVFVZDJ_MTUMARHDSA_N_000_000000
PubChem Compound ID  6918120