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2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone
A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4', 2-hydroxy benzyl group at position 3' and methoxy group at position 6'. It is isolated from the aerial parts of Ellipeiopsis cherrevensis and exhibits antibacterial, antimalarial and antineoplastic activity.

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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antimicrobial drug [CHEBI:36043] > antiprotozoal drug [CHEBI:35820]
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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 biochemical uses [CHEBI:52206] (3306) 
 metabolite [CHEBI:25212] (2692) 
 secondary metabolite [CHEBI:26619] (2225) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 antimicrobial agent [CHEBI:33281] (927) 
 antibacterial agent [CHEBI:33282] (317) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 antimicrobial drug [CHEBI:36043] (169) 
 antiprotozoal drug [CHEBI:35820] (168) 
 antimalarial [CHEBI:38068] (89) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 antineoplastic agent [CHEBI:35610] (760) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 alpha,beta-unsaturated ketone [CHEBI:51721] (238) 
 enone [CHEBI:51689] (233) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 flavonoids [CHEBI:72544] (433) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 alpha,beta-unsaturated ketone [CHEBI:51721] (238) 
 enone [CHEBI:51689] (233) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organochalcogen compound [CHEBI:36962] (11874) 
 organooxygen compound [CHEBI:36963] (11352) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 alpha,beta-unsaturated ketone [CHEBI:51721] (238) 
 enone [CHEBI:51689] (233) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 flavonoids [CHEBI:72544] (433) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 alpha,beta-unsaturated ketone [CHEBI:51721] (238) 
 enone [CHEBI:51689] (233) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 aromatic compound [CHEBI:33655] (3799) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic aromatic compound [CHEBI:33659] (3593) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 organic oxo compound [CHEBI:36587] (5932) 
 carbonyl compound [CHEBI:36586] (5928) 
 ketone [CHEBI:17087] (1288) 
 alpha,beta-unsaturated ketone [CHEBI:51721] (238) 
 enone [CHEBI:51689] (233) 
 chalcones [CHEBI:23086] (25) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 phenols [CHEBI:33853] (868) 
 benzenediols [CHEBI:33570] (188) 
 resorcinols [CHEBI:33572] (46) 
 2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone [CHEBI:65777] (1)
ChEBI Compound Accession Identifier:   [CHEBI:65777]
ChEBI Compound Description:   A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4', 2-hydroxy benzyl group at position 3' and methoxy group at position 6'. It is isolated from the aerial parts of Ellipeiopsis cherrevensis and exhibits antibacterial, antimalarial and antineoplastic activity.
ChEBI Compound Identification Number:   65777
ChEBI InChI Value:   InChI=1S/C23H20O5/c1-28-21-14-20(26)17(13-16-9-5-6-10-18(16)24)23(27)22(21)19(25)12-11-15-7-3-2-4-8-15/h2-12,14,24,26-27H,13H2,1H3/b12-11+
ChEBI InChIKey Value:   IVKGLRZLTNXWKF-VAWYXSNFSA-N
ChEBI Compound Name:   2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone
ChEBI SMILES Value:   COc1cc(O)c(Cc2ccccc2O)c(O)c1C(=O)\C=C\c1ccccc1
ChEBI Substance ID:   160709450
ChEBI URL:   ChEBI:65777
ChemSpider ID:   21375497
Ontomatica Chemical Accession Key (OnChAKey):   IVKGLRZLTNXWKF_VAWYXSNFSA_N_000_000000
PubChem Compound ID:   26249303