Item 385 of 661 (back to results) previous next 3-hydroxymethyl-4-methyl-furan-2(5H)-one A butenolide that is furan-2(5H)-one substituted by a hydroxymethyl group at position 3 and a methyl group at position 4. Isolated from an edible mushroom Mycoleptodonoides aitchisonii, it exhibits protective activity against endoplasmic reticulum (ER) stress dependent cell death.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > metabolite [CHEBI:25212] > secondary metabolite [CHEBI:26619] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   metabolite [CHEBI:25212] (2692)   secondary metabolite [CHEBI:26619] (2225)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   protective agent [CHEBI:50267] (74)   neuroprotective agent [CHEBI:63726] (30)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   primary alcohol [CHEBI:15734] (167)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  p-block molecular entity [CHEBI:33675] (25343)   chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   primary alcohol [CHEBI:15734] (167)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   primary alcohol [CHEBI:15734] (167)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  ester [CHEBI:35701] (3370)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   monocyclic compound [CHEBI:33661] (2007)   heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  heteromonocyclic compound [CHEBI:33670] (2004)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteromonocyclic compound [CHEBI:25693] (2004)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  oxacycle [CHEBI:38104] (2002)   furans [CHEBI:24129] (114)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic ester [CHEBI:33308] (1495)   lactone [CHEBI:25000] (516)   gamma-lactone [CHEBI:37581] (157)   butenolide [CHEBI:50523] (45)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   organic hydroxy compound [CHEBI:33822] (3050)   alcohol [CHEBI:30879] (1371)   primary alcohol [CHEBI:15734] (167)   3-hydroxymethyl-4-methyl-furan-2(5H)-one [CHEBI:66047] (1) ChEBI Compound Accession Identifier:   [CHEBI:66047] ChEBI Compound Description:   A butenolide that is furan-2(5H)-one substituted by a hydroxymethyl group at position 3 and a methyl group at position 4. Isolated from an edible mushroom Mycoleptodonoides aitchisonii, it exhibits protective activity against endoplasmic reticulum (ER) stress dependent cell death. ChEBI Compound Identification Number:   66047 ChEBI InChI Value:   InChI=1S/C6H8O3/c1-4-3-9-6(8)5(4)2-7/h7H,2-3H2,1H3 ChEBI InChIKey Value:   HVNDECDCMWQSGR-UHFFFAOYSA-N ChEBI Compound Name:   3-hydroxymethyl-4-methyl-furan-2(5H)-one ChEBI SMILES Value:   CC1=C(CO)C(=O)OC1 ChEBI Substance ID:   160709842 ChEBI URL:   ChEBI:66047 ChemSpider ID:   NS Ontomatica Chemical Accession Key (OnChAKey):   HVNDECDCMWQSGR_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   25178260