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emedastine difumarate
The fumaric acid salt of emedastine containing two molecules of fumaric acid for each molecule of emedastine. A relatively selective histamine H1 antagonist, it is used for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.


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05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] > dermatologic drug [CHEBI:50177]
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03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 pharmacological uses [CHEBI:52210] (736) 
 neurotransmitter agent [CHEBI:35942] (471) 
 histaminergic drug [CHEBI:37957] (94) 
 histamine antagonist [CHEBI:37956] (87) 
 H1-receptor antagonist [CHEBI:37955] (57) 
 emedastine difumarate [CHEBI:59865] (1)
05. Industrial Uses 
05. Industrial Uses
 pharmaceutical [CHEBI:52217] (1978) 
 drug [CHEBI:23888] (1930) 
 dermatologic drug [CHEBI:50177] (49) 
 antipruritic drug [CHEBI:59683] (18) 
 emedastine difumarate [CHEBI:59865] (1)
 anti-allergic agent [CHEBI:50857] (51) 
 emedastine difumarate [CHEBI:59865] (1)
08. Chemical Category 
08. Chemical Category
 polyatomic entity [CHEBI:36357] (18777) 
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 salt [CHEBI:24866] (931) 
 organic salt [CHEBI:24868] (775) 
 fumarate salt [CHEBI:50921] (9) 
 emedastine difumarate [CHEBI:59865] (1)
ChEBI Compound Accession Identifier  [CHEBI:59865]
ChEBI Compound Description  The fumaric acid salt of emedastine containing two molecules of fumaric acid for each molecule of emedastine. A relatively selective histamine H1 antagonist, it is used for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
ChEBI Compound Identification Number  59865
ChEBI InChI Value  "InChI=1S/C17H26N4O.2C4H4O4/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20;2*5-3(6)1-2-4(7)8/h4-5,7-8H,3,6,9-14H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-"
ChEBI InChIKey Value  FWLKKPKZQYVAFR-SPIKMXEPSA-N
ChEBI Compound Name  emedastine difumarate
ChEBI SMILES Value  OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O.CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1
ChEBI Substance ID  99319669
ChEBI URL  ChEBI:59865
ChemSpider ID  26331734
Ontomatica Chemical Accession Key (OnChAKey)  FWLKKPKZQYVAFR_SPIKMXEPSA_N_000_000000
PubChem Compound ID  46878555