Item 5 of 141 (back to results) previous next bicuculline Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

Current search: 08. Chemical Category: main group molecular entity [CHEBI:33579] > p-block molecular entity [CHEBI:33675] × 05. Industrial Uses: agrochemical [CHEBI:33286] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biophysical uses [CHEBI:52208] (136)   membrane transport modulator [CHEBI:38632] (122)   GABA-gated chloride channel antagonist [CHEBI:38999] (6)   bicuculline [CHEBI:3092] (1)  aetiopathogenetic uses [CHEBI:52209] (178)   neurotoxin [CHEBI:50910] (26)   bicuculline [CHEBI:3092] (1)  pharmacological uses [CHEBI:52210] (736)   neurotransmitter agent [CHEBI:35942] (471)   GABA agent [CHEBI:51374] (7)   GABA antagonist [CHEBI:65259] (3)   bicuculline [CHEBI:3092] (1) 05. Industrial Uses  05. 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It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. ChEBI Compound Identification Number:   3092 ChEBI InChI Value:   InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 ChEBI InChIKey Value:   IYGYMKDQCDOMRE-ZWKOTPCHSA-N ChEBI Compound Name:   bicuculline ChEBI SMILES Value:   [H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@@]1([H])N(C)CCc2cc3OCOc3cc12 ChEBI Substance ID:   85305365 ChEBI URL:   ChEBI:3092 ChemSpider ID:   9820 Ontomatica Chemical Accession Key (OnChAKey):   IYGYMKDQCDOMRE_ZWKOTPCHSA_N_000_000000 PubChem Compound ID:   10237