Item 6 of 8 (back to results) previous next pitavastatin A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] > enzyme inhibitor [CHEBI:23924] > hydroxymethylglutaryl-CoA reductase inhibitor [CHEBI:35664] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] > drug [CHEBI:23888] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   hydroxymethylglutaryl-CoA reductase inhibitor [CHEBI:35664] (10)   pitavastatin [CHEBI:32020] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antilipemic drug [CHEBI:35679] (30)   anticholesteremic drug [CHEBI:35821] (15)   pitavastatin [CHEBI:32020] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   s-block molecular entity [CHEBI:33674] (7287)   hydrogen molecular entity [CHEBI:33608] (6932)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic hydroxy compound [CHEBI:33822] (3050)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  p-block molecular entity [CHEBI:33675] (25343)   halogen molecular entity [CHEBI:24471] (1475)   fluorine molecular entity [CHEBI:24062] (288)   organofluorine compound [CHEBI:37143] (275)   pitavastatin [CHEBI:32020] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   pitavastatin [CHEBI:32020] (1)  pnictogen molecular entity [CHEBI:33302] (10027)   nitrogen molecular entity [CHEBI:51143] (7930)   organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  chalcogen molecular entity [CHEBI:33304] (15225)   oxygen molecular entity [CHEBI:25806] (14414)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic hydroxy compound [CHEBI:33822] (3050)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organonitrogen compound [CHEBI:35352] (6705)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   pitavastatin [CHEBI:32020] (1)  organochalcogen compound [CHEBI:36962] (11874)   organooxygen compound [CHEBI:36963] (11352)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic hydroxy compound [CHEBI:33822] (3050)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic acid [CHEBI:64709] (3008)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  carbocyclic compound [CHEBI:33598] (1130)   cyclopropanes [CHEBI:51454] (58)   pitavastatin [CHEBI:32020] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   homocyclic compound [CHEBI:33597] (1134)   carbocyclic compound [CHEBI:33598] (1130)   cyclopropanes [CHEBI:51454] (58)   pitavastatin [CHEBI:32020] (1)  polycyclic compound [CHEBI:33635] (4078)   heteropolycyclic compound [CHEBI:33671] (2613)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  bicyclic compound [CHEBI:33636] (1511)   heterobicyclic compound [CHEBI:33672] (1315)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  aromatic compound [CHEBI:33655] (3799)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  carbocyclic compound [CHEBI:33598] (1130)   cyclopropanes [CHEBI:51454] (58)   pitavastatin [CHEBI:32020] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  heteropolycyclic compound [CHEBI:33671] (2613)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  heterobicyclic compound [CHEBI:33672] (1315)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organonitrogen heterocyclic compound [CHEBI:38101] (3202)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterobicyclic compound [CHEBI:27171] (1315)   quinolines [CHEBI:26513] (132)   pitavastatin [CHEBI:32020] (1)  carbocyclic compound [CHEBI:33598] (1130)   cyclopropanes [CHEBI:51454] (58)   pitavastatin [CHEBI:32020] (1)  organic oxo compound [CHEBI:36587] (5932)   carbonyl compound [CHEBI:36586] (5928)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  heteroatomic molecular entity [CHEBI:37577] (13672)   hydroxides [CHEBI:24651] (5641)   oxoacid [CHEBI:24833] (3119)   carbon oxoacid [CHEBI:35605] (3012)   carboxylic acid [CHEBI:33575] (3005)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  monocarboxylic acid [CHEBI:25384] (1620)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  organic hydroxy compound [CHEBI:33822] (3050)   hydroxy carboxylic acid [CHEBI:24669] (422)   hydroxy monocarboxylic acid [CHEBI:35868] (396)   dihydroxy monocarboxylic acid [CHEBI:35972] (45)   pitavastatin [CHEBI:32020] (1)  halide [CHEBI:37578] (1402)   organohalogen compound [CHEBI:36684] (976)   organofluorine compound [CHEBI:37143] (275)   pitavastatin [CHEBI:32020] (1) 09. Chemical Capabilities  09. Chemical Capabilities  antioxidant [CHEBI:22586] (199)   pitavastatin [CHEBI:32020] (1) ChEBI Compound Accession Identifier:   [CHEBI:32020] ChEBI Compound Description:   A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise. ChEBI Compound Identification Number:   32020 ChEBI InChI Value:   InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/b12-11+/t18-,19-/m1/s1 ChEBI InChIKey Value:   VGYFMXBACGZSIL-MCBHFWOFSA-N ChEBI Compound Name:   pitavastatin ChEBI SMILES Value:   O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC(O)=O ChEBI Substance ID:   160655727 ChEBI URL:   ChEBI:32020 ChemSpider ID:   4445604 Ontomatica Chemical Accession Key (OnChAKey):   VGYFMXBACGZSIL_MCBHFWOFSA_N_000_000000 PubChem Compound ID:   5282452