Item 10 of 12 (back to results) previous next hycanthone A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

Current search: 08. Chemical Category: polyatomic entity [CHEBI:36357] > molecule [CHEBI:25367] > cyclic compound [CHEBI:33595] > polycyclic compound [CHEBI:33635] > organic polycyclic compound [CHEBI:51958] > organic tricyclic compound [CHEBI:51959] × 03. Biological Effects of Specific Chemicals: aetiopathogenetic uses [CHEBI:52209] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  aetiopathogenetic uses [CHEBI:52209] (178)   genotoxin [CHEBI:50902] (78)   mutagen [CHEBI:25435] (74)   hycanthone [CHEBI:52768] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antiinfective agent [CHEBI:35441] (82)   antiparasitic agent [CHEBI:35442] (30)   anthelminthic drug [CHEBI:35443] (20)   antiplatyhelmintic drug [CHEBI:35684] (8)   schistosomicide drug [CHEBI:38941] (7)   hycanthone [CHEBI:52768] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   heteroorganic entity [CHEBI:33285] (15197)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   polycyclic compound [CHEBI:33635] (4078)   heteropolycyclic compound [CHEBI:33671] (2613)   heterotricyclic compound [CHEBI:36688] (541)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  heterocyclic compound [CHEBI:5686] (5275)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  heteropolycyclic compound [CHEBI:33671] (2613)   heterotricyclic compound [CHEBI:36688] (541)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic heterocyclic compound [CHEBI:24532] (5243)   organic heteropolycyclic compound [CHEBI:38166] (2613)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1)  organic polycyclic compound [CHEBI:51958] (1654)   organic tricyclic compound [CHEBI:51959] (755)   organic heterotricyclic compound [CHEBI:26979] (541)   thioxanthenes [CHEBI:50930] (8)   hycanthone [CHEBI:52768] (1) ChEBI Compound Accession Identifier:   [CHEBI:52768] ChEBI Compound Description:   A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel. ChEBI Compound Identification Number:   52768 ChEBI InChI Value:   InChI=1S/C20H24N2O2S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20/h5-10,21,23H,3-4,11-13H2,1-2H3 ChEBI InChIKey Value:   MFZWMTSUNYWVBU-UHFFFAOYSA-N ChEBI Compound Name:   hycanthone ChEBI SMILES Value:   CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 ChEBI Substance ID:   85096689 ChEBI URL:   ChEBI:52768 ChemSpider ID:   3508 Ontomatica Chemical Accession Key (OnChAKey):   MFZWMTSUNYWVBU_UHFFFAOYSA_N_000_000000 PubChem Compound ID:   3634