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(+)-(11R,2'S)-erythro-mefloquine
"An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown."

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08. Chemical Category: polyatomic entity [CHEBI:36357] > molecule [CHEBI:25367] > organic molecule [CHEBI:72695]
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03. Biological Effects of Specific Chemicals: antimicrobial agent [CHEBI:33281] > antimicrobial drug [CHEBI:36043] > antiprotozoal drug [CHEBI:35820] > antimalarial [CHEBI:38068]
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more general categories    information about this item
03. Biological Effects of Specific Chemicals 
03. Biological Effects of Specific Chemicals
 antimicrobial agent [CHEBI:33281] (927) 
 antimicrobial drug [CHEBI:36043] (169) 
 antiprotozoal drug [CHEBI:35820] (168) 
 antimalarial [CHEBI:38068] (89) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
08. Chemical Category 
08. Chemical Category
 main group molecular entity [CHEBI:33579] (25650) 
 s-block molecular entity [CHEBI:33674] (7287) 
 hydrogen molecular entity [CHEBI:33608] (6932) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 p-block molecular entity [CHEBI:33675] (25343) 
 halogen molecular entity [CHEBI:24471] (1475) 
 fluorine molecular entity [CHEBI:24062] (288) 
 organofluorine compound [CHEBI:37143] (275) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 halide [CHEBI:37578] (1402) 
 organohalogen compound [CHEBI:36684] (976) 
 organofluorine compound [CHEBI:37143] (275) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 pnictogen molecular entity [CHEBI:33302] (10027) 
 nitrogen molecular entity [CHEBI:51143] (7930) 
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 chalcogen molecular entity [CHEBI:33304] (15225) 
 oxygen molecular entity [CHEBI:25806] (14414) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 carbon group molecular entity [CHEBI:33582] (23847) 
 organic molecular entity [CHEBI:50860] (23769) 
 heteroorganic entity [CHEBI:33285] (15197) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen compound [CHEBI:35352] (6705) 
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organohalogen compound [CHEBI:36684] (976) 
 organofluorine compound [CHEBI:37143] (275) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 polyatomic entity [CHEBI:36357] (18777) 
 molecule [CHEBI:25367] (11520) 
 cyclic compound [CHEBI:33595] (7817) 
 polycyclic compound [CHEBI:33635] (4078) 
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 bicyclic compound [CHEBI:33636] (1511) 
 heterobicyclic compound [CHEBI:33672] (1315) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 aromatic compound [CHEBI:33655] (3799) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 monocyclic compound [CHEBI:33661] (2007) 
 heteromonocyclic compound [CHEBI:33670] (2004) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 heterocyclic compound [CHEBI:5686] (5275) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 heteromonocyclic compound [CHEBI:33670] (2004) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 heteropolycyclic compound [CHEBI:33671] (2613) 
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 heterobicyclic compound [CHEBI:33672] (1315) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic molecule [CHEBI:72695] (11399) 
 organic cyclic compound [CHEBI:33832] (7633) 
 organic heterocyclic compound [CHEBI:24532] (5243) 
 organic heteromonocyclic compound [CHEBI:25693] (2004) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organonitrogen heterocyclic compound [CHEBI:38101] (3202) 
 piperidines [CHEBI:26151] (143) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 organic heteropolycyclic compound [CHEBI:38166] (2613) 
 organic heterobicyclic compound [CHEBI:27171] (1315) 
 quinolines [CHEBI:26513] (132) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 heteroatomic molecular entity [CHEBI:37577] (13672) 
 hydroxides [CHEBI:24651] (5641) 
 organic hydroxy compound [CHEBI:33822] (3050) 
 alcohol [CHEBI:30879] (1371) 
 secondary alcohol [CHEBI:35681] (342) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
 halide [CHEBI:37578] (1402) 
 organohalogen compound [CHEBI:36684] (976) 
 organofluorine compound [CHEBI:37143] (275) 
 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [CHEBI:63681] (3) 
 (+)-(11R,2'S)-erythro-mefloquine [CHEBI:63684] (1)
ChEBI Compound Accession Identifier:   [CHEBI:63684]
ChEBI Compound Description:   "An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown."
ChEBI Compound Identification Number:   63684
ChEBI InChI Value:   InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m0/s1
ChEBI InChIKey Value:   XEEQGYMUWCZPDN-SWLSCSKDSA-N
ChEBI Compound Name:   (+)-(11R,2'S)-erythro-mefloquine
ChEBI SMILES Value:   O[C@@H]([C@@H]1CCCCN1)c1cc(nc2c(cccc12)C(F)(F)F)C(F)(F)F
ChEBI Substance ID:   135611148
ChEBI URL:   ChEBI:63684
ChemSpider ID:   401792
Ontomatica Chemical Accession Key (OnChAKey):   XEEQGYMUWCZPDN_SWLSCSKDSA_N_000_000000
PubChem Compound ID:   456309