Item 944 of 946 (back to results) previous next dutasteride Finasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.

Current search: 03. Biological Effects of Specific Chemicals: biochemical uses [CHEBI:52206] × 05. Industrial Uses: pharmaceutical [CHEBI:52217] × Select any link to see items in a related category. more general categories    information about this item 03. Biological Effects of Specific Chemicals  03. Biological Effects of Specific Chemicals  biochemical uses [CHEBI:52206] (3306)   enzyme inhibitor [CHEBI:23924] (825)   5alpha-reductase inhibitor [CHEBI:50781] (6)   dutasteride [CHEBI:521033] (1) 05. Industrial Uses  05. Industrial Uses  pharmaceutical [CHEBI:52217] (1978)   drug [CHEBI:23888] (1930)   antihyperplasia drug [CHEBI:59844] (3)   dutasteride [CHEBI:521033] (1) 08. Chemical Category  08. Chemical Category  main group molecular entity [CHEBI:33579] (25650)   p-block molecular entity [CHEBI:33675] (25343)   carbon group molecular entity [CHEBI:33582] (23847)   organic molecular entity [CHEBI:50860] (23769)   lipid [CHEBI:18059] (3532)   steroid [CHEBI:35341] (716)   aza-steroid [CHEBI:35726] (2)   dutasteride [CHEBI:521033] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   aza-steroid [CHEBI:35726] (2)   dutasteride [CHEBI:521033] (1)  polyatomic entity [CHEBI:36357] (18777)   molecule [CHEBI:25367] (11520)   cyclic compound [CHEBI:33595] (7817)   polycyclic compound [CHEBI:33635] (4078)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   aza-steroid [CHEBI:35726] (2)   dutasteride [CHEBI:521033] (1)  organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   aza-steroid [CHEBI:35726] (2)   dutasteride [CHEBI:521033] (1)  organic molecule [CHEBI:72695] (11399)   organic cyclic compound [CHEBI:33832] (7633)   organic polycyclic compound [CHEBI:51958] (1654)   steroid [CHEBI:35341] (716)   aza-steroid [CHEBI:35726] (2)   dutasteride [CHEBI:521033] (1) ChEBI Compound Accession Identifier:   [CHEBI:521033] ChEBI Compound Description:   Finasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. ChEBI Compound Identification Number:   521033 ChEBI InChI Value:   InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1 ChEBI InChIKey Value:   JWJOTENAMICLJG-QWBYCMEYSA-N ChEBI Compound Name:   dutasteride ChEBI SMILES Value:   [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])(C(=O)Nc5cc(ccc5C(F)(F)F)C(F)(F)F)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2 ChEBI Substance ID:   85709776 ChEBI URL:   ChEBI:521033 ChemSpider ID:   5293502 Ontomatica Chemical Accession Key (OnChAKey):   JWJOTENAMICLJG_QWBYCMEYSA_N_000_000000 PubChem Compound ID:   6918296