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 trilostane
C009954
 
  
  
  

MeSH Unique Identifier: C009954
Scope Notes: Inhibits conversion of pregnenolone to progesterone; adrenal blocking agent used in treatment of Cushing's syndrome
Chemical – Gene Interaction

Note 1: FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone]

Note 2: FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone]

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C20. Immune System Diseases: Z. Exceptions
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1. Human Genes 
1. Human Genes
 Endogenous Ligands [HGNC:ENDOLIG] (1191) 
 follicle stimulating hormone, beta polypeptide [HGNC:FSHB] (68)
2. Interaction: Human Genes and Chemicals 
2. Interaction: Human Genes and Chemicals
 Affects (3990) 
 cotreatment (1499)
 Decreases (5154) 
 reaction (3393)
 Increases (5571) 
 abundance (630)
C01. Bacterial Infections and Mycoses 
C01. Bacterial Infections and Mycoses
 Infection [MESH:D007239] (4109) 
 Urinary Tract Infections [MESH:D014552] (984)
C04. Neoplasms 
C04. Neoplasms
 Neoplasms [MESH:D009369] (10293) 
 Cysts [MESH:D003560] (2625) 
 Ovarian Cysts [MESH:D010048] (2534) 
 Polycystic Ovary Syndrome [MESH:D011085] (2186)
 Neoplasms by Histologic Type [MESH:D009370] (8793) 
 Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742) 
 Neoplasms, Muscle Tissue [MESH:D009379] (1965) 
 Myoma [MESH:D009214] (203) 
 Rhabdomyoma [MESH:D012207] (200)
 Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126) 
 Neuroectodermal Tumors [MESH:D017599] (5066) 
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroendocrine Tumors [MESH:D018358] (3633) 
 Carcinoma, Neuroendocrine [MESH:D018278] (262) 
 Carcinoma, Medullary [MESH:D018276] (181)
 Neoplasms, Glandular and Epithelial [MESH:D009375] (7760) 
 Adenoma [MESH:D000236] (4051)
 Carcinoma [MESH:D002277] (7263) 
 Carcinoma, Transitional Cell [MESH:D002295] (2662)
 Adenocarcinoma [MESH:D000230] (6565) 
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Carcinoma, Neuroendocrine [MESH:D018278] (262) 
 Carcinoma, Medullary [MESH:D018276] (181)
 Carcinoma in Situ [MESH:D002278] (2111) 
 Prostatic Intraepithelial Neoplasia [MESH:D019048] (1565)
 Neoplasms, Ductal, Lobular, and Medullary [MESH:D018299] (1831) 
 Carcinoma, Medullary [MESH:D018276] (181)
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neoplasms, Nerve Tissue [MESH:D009380] (5201) 
 Neuroectodermal Tumors [MESH:D017599] (5059) 
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroendocrine Tumors [MESH:D018358] (3625) 
 Carcinoma, Neuroendocrine [MESH:D018278] (184) 
 Carcinoma, Medullary [MESH:D018276] (181)
 Neoplasms by Site [MESH:D009371] (9169) 
 Bone Neoplasms [MESH:D001859] (1334)
 Breast Neoplasms [MESH:D001943] (6077)
 Digestive System Neoplasms [MESH:D004067] (7487) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Gastrointestinal Neoplasms [MESH:D005770] (6452) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Intestinal Neoplasms [MESH:D007414] (5358) 
 Colorectal Neoplasms [MESH:D015179] (5294)
 Liver Neoplasms [MESH:D008113] (6048) 
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Endocrine Gland Neoplasms [MESH:D004701] (4925) 
 Adrenal Gland Neoplasms [MESH:D000310] (917)
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Pituitary Neoplasms [MESH:D010911] (981)
 Thyroid Neoplasms [MESH:D013964] (2040)
 Head and Neck Neoplasms [MESH:D006258] (4612) 
 Thyroid Neoplasms [MESH:D013964] (2040)
 Mammary Neoplasms, Animal [MESH:D015674] (3404) 
 Mammary Neoplasms, Experimental [MESH:D008325] (3268)
 Nervous System Neoplasms [MESH:D009423] (3130) 
 Central Nervous System Neoplasms [MESH:D016543] (3055) 
 Brain Neoplasms [MESH:D001932] (2764) 
 Supratentorial Neoplasms [MESH:D015173] (930) 
 Hypothalamic Neoplasms [MESH:D007029] (922) 
 Pituitary Neoplasms [MESH:D010911] (914)
 Paraneoplastic Syndromes, Nervous System [MESH:D020361] (218) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Thoracic Neoplasms [MESH:D013899] (6032) 
 Respiratory Tract Neoplasms [MESH:D012142] (6020) 
 Lung Neoplasms [MESH:D008175] (6015) 
 Bronchial Neoplasms [MESH:D001984] (3608) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
 Urogenital Neoplasms [MESH:D014565] (7002) 
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Neoplasms, Experimental [MESH:D009374] (5218) 
 Mammary Neoplasms, Experimental [MESH:D008325] (3268)
 Neoplastic Processes [MESH:D009385] (5317) 
 Neoplasm Invasiveness [MESH:D009361] (3388)
 Neoplasm Metastasis [MESH:D009362] (4441)
 Neoplasm Recurrence, Local [MESH:D009364] (1949)
 Paraneoplastic Syndromes [MESH:D010257] (231) 
 Paraneoplastic Endocrine Syndromes [MESH:D009384] (207) 
 ACTH Syndrome, Ectopic [MESH:D000182] (200)
 Paraneoplastic Syndromes, Nervous System [MESH:D020361] (218) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
C05. Musculoskeletal Diseases 
C05. Musculoskeletal Diseases
 Musculoskeletal Diseases [MESH:D009140] (8705) 
 Bone Diseases [MESH:D001847] (5801) 
 Bone Neoplasms [MESH:D001859] (1334)
 Osteoarthropathy, Primary Hypertrophic [MESH:D010004] (94)
 Bone Diseases, Developmental [MESH:D001848] (3315) 
 Dysostoses [MESH:D004413] (1019) 
 Synostosis [MESH:D013580] (817) 
 Multiple Synostoses Syndrome 3 [MESH:C567839] (60)
 Bone Diseases, Endocrine [MESH:D001849] (747) 
 Acromegaly [MESH:D000172] (466)
 Bone Diseases, Metabolic [MESH:D001851] (3492) 
 Osteoporosis [MESH:D010024] (3037)
 Osteonecrosis [MESH:D010020] (539) 
 Femur Head Necrosis [MESH:D005271] (268)
 Jaw Diseases [MESH:D007571] (1601) 
 Jaw Abnormalities [MESH:D007569] (1435) 
 Cleft Palate [MESH:D002972] (1330)
 Joint Diseases [MESH:D007592] (4657) 
 Osteoarthropathy, Primary Hypertrophic [MESH:D010004] (94)
 Synovitis [MESH:D013585] (270)
 Arthritis [MESH:D001168] (4416) 
 Chondrocalcinosis [MESH:D002805] (213)
 Sacroiliitis [MESH:D058566] (202)
 Gout [MESH:D006073] (261) 
 Arthritis, Gouty [MESH:D015210] (211)
 Musculoskeletal Abnormalities [MESH:D009139] (3796) 
 Craniofacial Abnormalities [MESH:D019465] (3098) 
 Maxillofacial Abnormalities [MESH:D019767] (1447) 
 Jaw Abnormalities [MESH:D007569] (1438) 
 Cleft Palate [MESH:D002972] (1330)
 Synostosis [MESH:D013580] (817) 
 Multiple Synostoses Syndrome 3 [MESH:C567839] (60)
 Rheumatic Diseases [MESH:D012216] (4032) 
 Gout [MESH:D006073] (261) 
 Arthritis, Gouty [MESH:D015210] (211)
C06. Digestive System Diseases 
C06. Digestive System Diseases
 Digestive System Diseases [MESH:D004066] (9461) 
 Biliary Tract Diseases [MESH:D001660] (3845) 
 Bile Duct Diseases [MESH:D001649] (3512) 
 Cholestasis [MESH:D002779] (3419)
 Digestive System Neoplasms [MESH:D004067] (7493) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Gastrointestinal Neoplasms [MESH:D005770] (6460) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Colorectal Neoplasms [MESH:D015179] (5294)
 Liver Neoplasms [MESH:D008113] (6048) 
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Gastrointestinal Diseases [MESH:D005767] (7443) 
 Gastroenteritis [MESH:D005759] (4066) 
 Inflammatory Bowel Diseases [MESH:D015212] (3492) 
 Crohn Disease [MESH:D003424] (2585)
 Gastrointestinal Neoplasms [MESH:D005770] (6460) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Colorectal Neoplasms [MESH:D015179] (5294)
 Intestinal Diseases [MESH:D007410] (6206) 
 Colonic Diseases [MESH:D003108] (5564) 
 Colorectal Neoplasms [MESH:D015179] (5282)
 Inflammatory Bowel Diseases [MESH:D015212] (3492) 
 Crohn Disease [MESH:D003424] (2585)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Colorectal Neoplasms [MESH:D015179] (5294)
 Rectal Diseases [MESH:D012002] (4596) 
 Colorectal Neoplasms [MESH:D015179] (4534)
 Stomach Diseases [MESH:D013272] (5325) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Liver Diseases [MESH:D008107] (8167) 
 Fatty Liver [MESH:D005234] (3584) 
 Non-alcoholic Fatty Liver Disease [MESH:C541083] (1567)
 Hepatic Insufficiency [MESH:D048550] (2771) 
 Liver Failure [MESH:D017093] (2768) 
 Liver Failure, Acute [MESH:D017114] (2404)
 Liver Cirrhosis [MESH:D008103] (5542) 
 Liver Cirrhosis, Experimental [MESH:D008106] (4589)
 Liver Neoplasms [MESH:D008113] (6048) 
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Pancreatic Diseases [MESH:D010182] (4453) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
C07. Stomatognathic Diseases 
C07. Stomatognathic Diseases
 Stomatognathic Diseases [MESH:D009057] (5348) 
 Jaw Diseases [MESH:D007571] (1608) 
 Jaw Abnormalities [MESH:D007569] (1435) 
 Cleft Palate [MESH:D002972] (1330)
 Mouth Diseases [MESH:D009059] (4783) 
 Behcet Syndrome [MESH:D001528] (1784)
 Facial Paralysis [MESH:D005158] (238)
 Lip Diseases [MESH:D008047] (924) 
 Cleft Lip [MESH:D002971] (914)
 Mouth Abnormalities [MESH:D009056] (1383) 
 Cleft Lip [MESH:D002971] (914)
 Cleft Palate [MESH:D002972] (1330)
 Stomatognathic System Abnormalities [MESH:D018640] (1705) 
 Maxillofacial Abnormalities [MESH:D019767] (1447) 
 Jaw Abnormalities [MESH:D007569] (1438) 
 Cleft Palate [MESH:D002972] (1330)
 Mouth Abnormalities [MESH:D009056] (1383) 
 Cleft Lip [MESH:D002971] (914)
 Cleft Palate [MESH:D002972] (1330)
C08. Respiratory Tract Diseases 
C08. Respiratory Tract Diseases
 Respiratory Tract Diseases [MESH:D012140] (7881) 
 Bronchial Diseases [MESH:D001982] (4382) 
 Asthma [MESH:D001249] (4098)
 Lung Diseases [MESH:D008171] (7249) 
 Pneumonia [MESH:D011014] (3482)
 Pulmonary Embolism [MESH:D011655] (1118)
 Lung Diseases, Interstitial [MESH:D017563] (2966) 
 Idiopathic Interstitial Pneumonias [MESH:D054988] (314) 
 Idiopathic Pulmonary Fibrosis [MESH:D054990] (310)
 Lung Diseases, Obstructive [MESH:D008173] (4697) 
 Asthma [MESH:D001249] (3903)
 Lung Neoplasms [MESH:D008175] (6012) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
 Pulmonary Fibrosis [MESH:D011658] (3140) 
 Idiopathic Pulmonary Fibrosis [MESH:D054990] (310)
 Respiratory Hypersensitivity [MESH:D012130] (4401) 
 Asthma [MESH:D001249] (4098)
 Respiratory Tract Infections [MESH:D012141] (3926) 
 Pneumonia [MESH:D011014] (3482)
 Respiratory Tract Neoplasms [MESH:D012142] (6053) 
 Lung Neoplasms [MESH:D008175] (6013) 
 Bronchial Neoplasms [MESH:D001984] (3608) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
C09. Otorhinolaryngologic Diseases 
C09. Otorhinolaryngologic Diseases
 Otorhinolaryngologic Diseases [MESH:D010038] (3827) 
 Ear Diseases [MESH:D004427] (2522) 
 Hearing Disorders [MESH:D006311] (2103) 
 Hearing Loss [MESH:D034381] (2068) 
 Hearing Loss, Sensorineural [MESH:D006319] (1227) 
 Insulin-Like Growth Factor I Deficiency [MESH:C563867] (346)
C10. Nervous System Diseases 
C10. Nervous System Diseases
 Z. Exceptions (4027) 
 Not Fully Specified [NFS] (4027)
 Nervous System Diseases [MESH:D009422] (13325) 
 Restless Legs Syndrome [MESH:D012148] (379)
 Autoimmune Diseases of the Nervous System [MESH:D020274] (2238) 
 Myasthenia Gravis [MESH:D009157] (632)
 Demyelinating Autoimmune Diseases, CNS [MESH:D020278] (1732) 
 Multiple Sclerosis [MESH:D009103] (1716)
 Central Nervous System Diseases [MESH:D002493] (9745) 
 Brain Diseases [MESH:D001927] (9294) 
 Brain Edema [MESH:D001929] (1165)
 Brain Damage, Chronic [MESH:D001925] (311) 
 Cerebral Palsy [MESH:D002547] (300)
 Brain Neoplasms [MESH:D001932] (2764) 
 Supratentorial Neoplasms [MESH:D015173] (930) 
 Hypothalamic Neoplasms [MESH:D007029] (922) 
 Pituitary Neoplasms [MESH:D010911] (914)
 Cerebrovascular Disorders [MESH:D002561] (5542) 
 Carotid Artery Diseases [MESH:D002340] (1993)
 Brain Ischemia [MESH:D002545] (4873) 
 Brain Infarction [MESH:D020520] (2571) 
 Brain Stem Infarctions [MESH:D020526] (198) 
 Lateral Medullary Syndrome [MESH:D014854] (188)
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Arterial Diseases [MESH:D020765] (2463) 
 Cerebral Arterial Diseases [MESH:D002539] (2440) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Embolism and Thrombosis [MESH:D002542] (490) 
 Intracranial Thrombosis [MESH:D020767] (481) 
 Sinus Thrombosis, Intracranial [MESH:D012851] (356) 
 Sagittal Sinus Thrombosis [MESH:D020225] (223)
 Intracranial Hemorrhages [MESH:D020300] (3269) 
 Cerebral Hemorrhage [MESH:D002543] (2873)
 Stroke [MESH:D020521] (3702) 
 Brain Infarction [MESH:D020520] (2571) 
 Brain Stem Infarctions [MESH:D020526] (198) 
 Lateral Medullary Syndrome [MESH:D014854] (188)
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Dementia [MESH:D003704] (4498) 
 Alzheimer Disease [MESH:D000544] (4275)
 Epilepsy [MESH:D004827] (6274) 
 Epilepsies, Myoclonic [MESH:D004831] (1344)
 Seizures [MESH:D012640] (4502)
 Epilepsy, Generalized [MESH:D004829] (1431) 
 Epilepsy, Tonic-Clonic [MESH:D004830] (1042)
 Spasms, Infantile [MESH:D013036] (468)
 Hypothalamic Diseases [MESH:D007027] (1833) 
 Hypothalamic Neoplasms [MESH:D007029] (922) 
 Pituitary Neoplasms [MESH:D010911] (914)
 Pituitary Diseases [MESH:D010900] (1808) 
 Pituitary Neoplasms [MESH:D010911] (981)
 Hyperpituitarism [MESH:D006964] (1250) 
 Acromegaly [MESH:D000172] (466)
 Hyperprolactinemia [MESH:D006966] (603)
 Pituitary ACTH Hypersecretion [MESH:D047748] (599)
 Ocular Motility Disorders [MESH:D015835] (364) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Cranial Nerve Diseases [MESH:D003389] (2004) 
 Ocular Motility Disorders [MESH:D015835] (1697) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Demyelinating Diseases [MESH:D003711] (2917) 
 Demyelinating Autoimmune Diseases, CNS [MESH:D020278] (2035) 
 Multiple Sclerosis [MESH:D009103] (1716)
 Nervous System Neoplasms [MESH:D009423] (3073) 
 Central Nervous System Neoplasms [MESH:D016543] (3055) 
 Brain Neoplasms [MESH:D001932] (2764) 
 Supratentorial Neoplasms [MESH:D015173] (930) 
 Hypothalamic Neoplasms [MESH:D007029] (922) 
 Pituitary Neoplasms [MESH:D010911] (914)
 Neurodegenerative Diseases [MESH:D019636] (6613) 
 Paraneoplastic Syndromes, Nervous System [MESH:D020361] (218) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Tauopathies [MESH:D024801] (4289) 
 Alzheimer Disease [MESH:D000544] (4275)
 Neurologic Manifestations [MESH:D009461] (8964) 
 Neurogenic Inflammation [MESH:D020078] (2246)
 Seizures [MESH:D012640] (4514)
 Dyskinesias [MESH:D020820] (3365) 
 Catalepsy [MESH:D002375] (1429)
 Myoclonus [MESH:D009207] (427) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Neurobehavioral Manifestations [MESH:D019954] (5230) 
 Memory Disorders [MESH:D008569] (3233) 
 Amnesia [MESH:D000647] (1911)
 Neuromuscular Manifestations [MESH:D020879] (2130) 
 Muscular Atrophy [MESH:D009133] (1234)
 Pain [MESH:D010146] (3875) 
 Headache [MESH:D006261] (1416)
 Paralysis [MESH:D010243] (2043) 
 Facial Paralysis [MESH:D005158] (238)
 Sensation Disorders [MESH:D012678] (5011) 
 Hearing Disorders [MESH:D006311] (2103) 
 Hearing Loss [MESH:D034381] (2068) 
 Hearing Loss, Sensorineural [MESH:D006319] (1227) 
 Insulin-Like Growth Factor I Deficiency [MESH:C563867] (346)
 Somatosensory Disorders [MESH:D020886] (4000) 
 Hyperalgesia [MESH:D006930] (3929)
 Neuromuscular Diseases [MESH:D009468] (7336) 
 Peripheral Nervous System Diseases [MESH:D010523] (6151)
 Neuromuscular Junction Diseases [MESH:D020511] (712) 
 Myasthenia Gravis [MESH:D009157] (632)
 Sleep Disorders [MESH:D012893] (2050) 
 Dyssomnias [MESH:D020920] (1417) 
 Sleep Disorders, Intrinsic [MESH:D020919] (1270) 
 Restless Legs Syndrome [MESH:D012148] (379)
 Parasomnias [MESH:D020447] (453) 
 Restless Legs Syndrome [MESH:D012148] (379)
C11. Eye Diseases 
C11. Eye Diseases
 Z. Exceptions (245) 
 Not Fully Specified [NFS] (245)
 Eye Diseases [MESH:D005128] (6245) 
 Corneal Diseases [MESH:D003316] (1445)
 Eye Manifestations [MESH:D005132] (208) 
 Eye Pain [MESH:D058447] (207)
 Ocular Motility Disorders [MESH:D015835] (1699) 
 Opsoclonus-Myoclonus Syndrome [MESH:D053578] (202)
 Uveal Diseases [MESH:D014603] (2428) 
 Uveitis [MESH:D014605] (2157) 
 Panuveitis [MESH:D015864] (1805) 
 Uveitis, Anterior [MESH:D014606] (1791) 
 Behcet Syndrome [MESH:D001528] (1784)
C12. Male Urogenital Diseases 
C12. Male Urogenital Diseases
 Male Urogenital Diseases [MESH:D052801] (8891) 
 Genital Diseases, Male [MESH:D005832] (6794) 
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Infertility [MESH:D007246] (2909) 
 Infertility, Male [MESH:D007248] (2851) 
 Asthenozoospermia [MESH:D053627] (298)
 Oligospermia [MESH:D009845] (799) 
 Follicle-stimulating hormone deficiency, isolated [MESH:C537070] (185)
 Penile Diseases [MESH:D010409] (1805) 
 Hypospadias [MESH:D007021] (798)
 Prostatic Diseases [MESH:D011469] (6204) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urogenital Abnormalities [MESH:D014564] (2065) 
 Hypospadias [MESH:D007021] (798)
 Disorders of Sex Development [MESH:D012734] (1637) 
 Adrenogenital Syndrome [MESH:D047808] (715) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Urogenital Neoplasms [MESH:D014565] (6932) 
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Urologic Diseases [MESH:D014570] (7792) 
 Urinary Tract Infections [MESH:D014552] (984)
 Kidney Diseases [MESH:D007674] (7242) 
 Anuria [MESH:D001002] (833)
 Diabetes Insipidus [MESH:D003919] (354)
 Diabetic Nephropathies [MESH:D003928] (2301)
 Nephrocalcinosis [MESH:D009397] (311)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Nephritis [MESH:D009393] (4236) 
 Glomerulonephritis [MESH:D005921] (3758) 
 Glomerulonephritis, IGA [MESH:D005922] (897)
 Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)
 Nephrolithiasis [MESH:D053040] (492) 
 Kidney Calculi [MESH:D007669] (455)
 Nephrosis [MESH:D009401] (2228) 
 Nephrotic Syndrome [MESH:D009404] (1536)
 Renal Insufficiency [MESH:D051437] (4951) 
 Acute Kidney Injury [MESH:D058186] (4142) 
 Kidney Tubular Necrosis, Acute [MESH:D007683] (974)
 Renal Insufficiency, Chronic [MESH:D051436] (2931) 
 Kidney Failure, Chronic [MESH:D007676] (2930)
 Urinary Bladder Diseases [MESH:D001745] (4374) 
 Cystitis [MESH:D003556] (604)
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Urination Disorders [MESH:D014555] (3598) 
 Anuria [MESH:D001002] (833)
 Hematuria [MESH:D006417] (477)
 Oliguria [MESH:D009846] (307)
 Proteinuria [MESH:D011507] (3293)
 Urolithiasis [MESH:D052878] (585) 
 Nephrolithiasis [MESH:D053040] (492) 
 Kidney Calculi [MESH:D007669] (455)
 Urinary Calculi [MESH:D014545] (521) 
 Kidney Calculi [MESH:D007669] (455)
C13. Female Urogenital Diseases and Pregnancy Complications 
C13. Female Urogenital Diseases and Pregnancy Complications
 Z. Exceptions (1116) 
 Not Fully Specified [NFS] (1116)
 Female Urogenital Diseases [MESH:D052776] (8724) 
 Genital Diseases, Female [MESH:D005831] (5563) 
 Endometriosis [MESH:D004715] (2461)
 Adnexal Diseases [MESH:D000291] (4273) 
 Ovarian Diseases [MESH:D010049] (4255) 
 Ovarian Cysts [MESH:D010048] (2534) 
 Polycystic Ovary Syndrome [MESH:D011085] (2186)
 Infertility [MESH:D007246] (2211) 
 Infertility, Female [MESH:D007247] (2184)
 Urogenital Abnormalities [MESH:D014564] (2043) 
 Hypospadias [MESH:D007021] (798)
 Disorders of Sex Development [MESH:D012734] (1637) 
 Adrenogenital Syndrome [MESH:D047808] (715) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Urogenital Neoplasms [MESH:D014565] (5792) 
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Urologic Diseases [MESH:D014570] (7793) 
 Urinary Tract Infections [MESH:D014552] (984)
 Kidney Diseases [MESH:D007674] (7242) 
 Anuria [MESH:D001002] (833)
 Diabetes Insipidus [MESH:D003919] (354)
 Diabetic Nephropathies [MESH:D003928] (2301)
 Nephrocalcinosis [MESH:D009397] (311)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Carcinoma, Renal Cell [MESH:D002292] (2975)
 Nephritis [MESH:D009393] (4236) 
 Glomerulonephritis [MESH:D005921] (3758) 
 Glomerulonephritis, IGA [MESH:D005922] (897)
 Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)
 Nephrolithiasis [MESH:D053040] (492) 
 Kidney Calculi [MESH:D007669] (455)
 Nephrosis [MESH:D009401] (2228) 
 Nephrotic Syndrome [MESH:D009404] (1536)
 Renal Insufficiency [MESH:D051437] (4951) 
 Acute Kidney Injury [MESH:D058186] (4142) 
 Kidney Tubular Necrosis, Acute [MESH:D007683] (974)
 Renal Insufficiency, Chronic [MESH:D051436] (2931) 
 Kidney Failure, Chronic [MESH:D007676] (2930)
 Urinary Bladder Diseases [MESH:D001745] (4375) 
 Cystitis [MESH:D003556] (604)
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Urination Disorders [MESH:D014555] (3598) 
 Anuria [MESH:D001002] (833)
 Hematuria [MESH:D006417] (477)
 Oliguria [MESH:D009846] (307)
 Proteinuria [MESH:D011507] (3293)
 Urolithiasis [MESH:D052878] (585) 
 Nephrolithiasis [MESH:D053040] (492) 
 Kidney Calculi [MESH:D007669] (455)
 Urinary Calculi [MESH:D014545] (521) 
 Kidney Calculi [MESH:D007669] (455)
 Pregnancy Complications [MESH:D011248] (4768) 
 Abortion, Spontaneous [MESH:D000022] (2780)
 Hypertension, Pregnancy-Induced [MESH:D046110] (1453) 
 Pre-Eclampsia [MESH:D011225] (1435)
C14. Cardiovascular Diseases 
C14. Cardiovascular Diseases
 Cardiovascular Diseases [MESH:D002318] (10123) 
 Heart Diseases [MESH:D006331] (8614) 
 Cardiomegaly [MESH:D006332] (4081)
 Heart Failure [MESH:D006333] (4058)
 Arrhythmias, Cardiac [MESH:D001145] (4679) 
 Bradycardia [MESH:D001919] (1899)
 Long QT Syndrome [MESH:D008133] (693)
 Tachycardia [MESH:D013610] (3339)
 Ventricular Fibrillation [MESH:D014693] (624)
 Arrhythmia, Sinus [MESH:D001146] (324) 
 Sick Sinus Syndrome [MESH:D012804] (293)
 Heart Block [MESH:D006327] (571) 
 Sick Sinus Syndrome [MESH:D012804] (293)
 Cardiomyopathies [MESH:D009202] (5331) 
 Cardiomyopathy, Hypertrophic [MESH:D002312] (1516)
 Diabetic Cardiomyopathies [MESH:D058065] (1995)
 Heart Rupture [MESH:D006341] (141) 
 Heart Rupture, Post-Infarction [MESH:D006342] (137)
 Heart Valve Diseases [MESH:D006349] (3333) 
 Aortic Valve Stenosis [MESH:D001024] (1742) 
 Aortic Stenosis, Subvalvular [MESH:D001020] (1455) 
 Cardiomyopathy, Hypertrophic [MESH:D002312] (1451)
 Myocardial Ischemia [MESH:D017202] (5787) 
 Myocardial Infarction [MESH:D009203] (4122)
 Angina Pectoris [MESH:D000787] (2575) 
 Angina, Unstable [MESH:D000789] (782)
 Coronary Disease [MESH:D003327] (3439) 
 Coronary Artery Disease [MESH:D003324] (2685)
 Ventricular Outflow Obstruction [MESH:D014694] (976) 
 Aortic Valve Stenosis [MESH:D001024] (810) 
 Aortic Stenosis, Subvalvular [MESH:D001020] (203)
 Vascular Diseases [MESH:D014652] (8691) 
 Hypertension [MESH:D006973] (5655)
 Hypotension [MESH:D007022] (4045)
 Reperfusion Injury [MESH:D015427] (4968)
 Arterial Occlusive Diseases [MESH:D001157] (4520) 
 Arteriosclerosis [MESH:D001161] (4466) 
 Atherosclerosis [MESH:D050197] (4188)
 Coronary Artery Disease [MESH:D003324] (2685)
 Cerebrovascular Disorders [MESH:D002561] (5541) 
 Carotid Artery Diseases [MESH:D002340] (1993)
 Brain Ischemia [MESH:D002545] (4873) 
 Brain Infarction [MESH:D020520] (2571) 
 Brain Stem Infarctions [MESH:D020526] (198) 
 Lateral Medullary Syndrome [MESH:D014854] (188)
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Arterial Diseases [MESH:D020765] (2468) 
 Cerebral Arterial Diseases [MESH:D002539] (2440) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Embolism and Thrombosis [MESH:D002542] (550) 
 Intracranial Thrombosis [MESH:D020767] (481) 
 Sinus Thrombosis, Intracranial [MESH:D012851] (356) 
 Sagittal Sinus Thrombosis [MESH:D020225] (223)
 Intracranial Hemorrhages [MESH:D020300] (3269) 
 Cerebral Hemorrhage [MESH:D002543] (2873)
 Stroke [MESH:D020521] (3702) 
 Brain Infarction [MESH:D020520] (2571) 
 Brain Stem Infarctions [MESH:D020526] (198) 
 Lateral Medullary Syndrome [MESH:D014854] (188)
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Embolism and Thrombosis [MESH:D016769] (3374) 
 Embolism [MESH:D004617] (1137) 
 Pulmonary Embolism [MESH:D011655] (1118)
 Embolism, Fat [MESH:D004620] (261) 
 Embolism, Cholesterol [MESH:D017700] (255)
 Thromboembolism [MESH:D013923] (732) 
 Intracranial Embolism and Thrombosis [MESH:D002542] (550) 
 Intracranial Thrombosis [MESH:D020767] (481) 
 Sinus Thrombosis, Intracranial [MESH:D012851] (356) 
 Sagittal Sinus Thrombosis [MESH:D020225] (223)
 Thrombosis [MESH:D013927] (3101) 
 Venous Thrombosis [MESH:D020246] (1141)
 Thromboembolism [MESH:D013923] (732) 
 Intracranial Embolism and Thrombosis [MESH:D002542] (550) 
 Intracranial Thrombosis [MESH:D020767] (481) 
 Sinus Thrombosis, Intracranial [MESH:D012851] (356) 
 Sagittal Sinus Thrombosis [MESH:D020225] (223)
 Myocardial Ischemia [MESH:D017202] (5791) 
 Myocardial Infarction [MESH:D009203] (4151)
 Angina Pectoris [MESH:D000787] (2575) 
 Angina, Unstable [MESH:D000789] (782)
 Coronary Disease [MESH:D003327] (3439) 
 Coronary Artery Disease [MESH:D003324] (2685)
 Vasculitis [MESH:D014657] (2604) 
 Behcet Syndrome [MESH:D001528] (1784)
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
C15. Hemic and Lymphatic Diseases 
C15. Hemic and Lymphatic Diseases
 Hematologic Diseases [MESH:D006402] (6174) 
 Blood Coagulation Disorders [MESH:D001778] (1828) 
 Purpura [MESH:D011693] (475) 
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
 Hemorrhagic Disorders [MESH:D006474] (3359) 
 Plasminogen Activator Inhibitor-1 Deficiency [MESH:C567640] (328)
 Hemostatic Disorders [MESH:D020141] (2932) 
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities 
C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152) 
 Congenital Abnormalities [MESH:D000013] (8109) 
 Cardiovascular Abnormalities [MESH:D018376] (3294) 
 Heart Defects, Congenital [MESH:D006330] (2611) 
 Long QT Syndrome [MESH:D008133] (693)
 Musculoskeletal Abnormalities [MESH:D009139] (3779) 
 Craniofacial Abnormalities [MESH:D019465] (3064) 
 Maxillofacial Abnormalities [MESH:D019767] (1448) 
 Jaw Abnormalities [MESH:D007569] (1435) 
 Cleft Palate [MESH:D002972] (1330)
 Synostosis [MESH:D013580] (817) 
 Multiple Synostoses Syndrome 3 [MESH:C567839] (60)
 Stomatognathic System Abnormalities [MESH:D018640] (1705) 
 Maxillofacial Abnormalities [MESH:D019767] (1447) 
 Jaw Abnormalities [MESH:D007569] (1438) 
 Cleft Palate [MESH:D002972] (1330)
 Mouth Abnormalities [MESH:D009056] (1383) 
 Cleft Lip [MESH:D002971] (914)
 Cleft Palate [MESH:D002972] (1330)
 Urogenital Abnormalities [MESH:D014564] (2064) 
 Hypospadias [MESH:D007021] (798)
 Disorders of Sex Development [MESH:D012734] (1637) 
 Adrenogenital Syndrome [MESH:D047808] (715) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Genetic Diseases, Inborn [MESH:D030342] (9766) 
 Osteoarthropathy, Primary Hypertrophic [MESH:D010004] (94)
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Metabolism, Inborn Errors [MESH:D008661] (6032) 
 Purine-Pyrimidine Metabolism, Inborn Errors [MESH:D011686] (496) 
 Gout [MESH:D006073] (261) 
 Arthritis, Gouty [MESH:D015210] (211)
 Steroid Metabolism, Inborn Errors [MESH:D043202] (962) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
C17. Skin and Connective Tissue Diseases 
C17. Skin and Connective Tissue Diseases
 Skin Diseases [MESH:D012871] (8774) 
 Breast Diseases [MESH:D001941] (6148) 
 Breast Neoplasms [MESH:D001943] (6077)
 Hair Diseases [MESH:D006201] (1891) 
 Hirsutism [MESH:D006628] (323)
 Skin Diseases, Vascular [MESH:D017445] (3288) 
 Behcet Syndrome [MESH:D001528] (1784)
C18. Nutritional and Metabolic Diseases 
C18. Nutritional and Metabolic Diseases
 Metabolic Diseases [MESH:D008659] (9025) 
 Calcium Metabolism Disorders [MESH:D002128] (3634) 
 Hypocalcemia [MESH:D006996] (378)
 Calcinosis [MESH:D002114] (2989) 
 Nephrocalcinosis [MESH:D009397] (311)
 Glucose Metabolism Disorders [MESH:D044882] (6122) 
 Diabetes Mellitus [MESH:D003920] (5891) 
 Diabetes Mellitus, Experimental [MESH:D003921] (4771)
 Metabolism, Inborn Errors [MESH:D008661] (6028) 
 Purine-Pyrimidine Metabolism, Inborn Errors [MESH:D011686] (496) 
 Gout [MESH:D006073] (261) 
 Arthritis, Gouty [MESH:D015210] (211)
 Steroid Metabolism, Inborn Errors [MESH:D043202] (962) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Water-Electrolyte Imbalance [MESH:D014883] (2790) 
 Hypernatremia [MESH:D006955] (215)
 Hypocalcemia [MESH:D006996] (368)
 Hypokalemia [MESH:D007008] (1041)
 Nutrition Disorders [MESH:D009748] (4945) 
 Overnutrition [MESH:D044343] (4463) 
 Obesity [MESH:D009765] (4462) 
 Proopiomelanocortin Deficiency [MESH:C565726] (200)
C19. Endocrine System Diseases 
C19. Endocrine System Diseases
 Endocrine System Diseases [MESH:D004700] (8062) 
 Adrenal Gland Diseases [MESH:D000307] (2397) 
 Adrenal Cortex Diseases [MESH:D000303] (969)
 Adrenal Gland Neoplasms [MESH:D000310] (917)
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Adrenal Insufficiency [MESH:D000309] (1599) 
 Proopiomelanocortin Deficiency [MESH:C565726] (200)
 Adrenocortical Hyperfunction [MESH:D000308] (618) 
 Cushing Syndrome [MESH:D003480] (282)
 Diabetes Mellitus [MESH:D003920] (6159) 
 Diabetes Mellitus, Experimental [MESH:D003921] (4771)
 Diabetes Complications [MESH:D048909] (4129) 
 Diabetic Cardiomyopathies [MESH:D058065] (1995)
 Diabetic Nephropathies [MESH:D003928] (2301)
 Endocrine Gland Neoplasms [MESH:D004701] (4925) 
 Adrenal Gland Neoplasms [MESH:D000310] (917)
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Pituitary Neoplasms [MESH:D010911] (981)
 Thyroid Neoplasms [MESH:D013964] (2040)
 Gonadal Disorders [MESH:D006058] (5088) 
 Hypogonadism [MESH:D007006] (1123)
 Puberty, Delayed [MESH:D011628] (449)
 Puberty, Precocious [MESH:D011629] (1147)
 Disorders of Sex Development [MESH:D012734] (1637) 
 Adrenogenital Syndrome [MESH:D047808] (715) 
 Adrenal Hyperplasia, Congenital [MESH:D000312] (674) 
 Adrenal hyperplasia 2 [MESH:C538236] (89)
 Ovarian Diseases [MESH:D010049] (4253) 
 Ovarian Cysts [MESH:D010048] (2534) 
 Polycystic Ovary Syndrome [MESH:D011085] (2186)
 Pituitary Diseases [MESH:D010900] (1829) 
 Diabetes Insipidus [MESH:D003919] (302)
 Pituitary Neoplasms [MESH:D010911] (981)
 Hyperpituitarism [MESH:D006964] (1259) 
 Acromegaly [MESH:D000172] (466)
 Hyperprolactinemia [MESH:D006966] (603)
 Pituitary ACTH Hypersecretion [MESH:D047748] (599)
 Thyroid Diseases [MESH:D013959] (2808) 
 Thyroid Neoplasms [MESH:D013964] (2040)
C20. Immune System Diseases 
C20. Immune System Diseases
 Z. Exceptions (350) 
 Not Fully Specified [NFS] (350)
 Immune System Diseases [MESH:D007154] (7674) 
 Autoimmune Diseases [MESH:D001327] (5067) 
 Glomerulonephritis, IGA [MESH:D005922] (897)
 Autoimmune Diseases of the Nervous System [MESH:D020274] (2238) 
 Myasthenia Gravis [MESH:D009157] (632)
 Demyelinating Autoimmune Diseases, CNS [MESH:D020278] (1732) 
 Multiple Sclerosis [MESH:D009103] (1716)
 Hypersensitivity [MESH:D006967] (5873) 
 Hypersensitivity, Immediate [MESH:D006969] (4980) 
 Respiratory Hypersensitivity [MESH:D012130] (4250) 
 Asthma [MESH:D001249] (3914)
 Immune Complex Diseases [MESH:D007105] (782) 
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
C22. Animal Diseases 
C22. Animal Diseases
 Animal Diseases [MESH:D000820] (3656) 
 Mammary Neoplasms, Animal [MESH:D015674] (2735)
C23. Pathological Conditions, Signs and Symptoms 
C23. Pathological Conditions, Signs and Symptoms
 Pathological Conditions, Anatomical [MESH:D020763] (6074) 
 Atrophy [MESH:D001284] (2603) 
 Muscular Atrophy [MESH:D009133] (1234)
 Calculi [MESH:D002137] (756) 
 Urinary Calculi [MESH:D014545] (521) 
 Kidney Calculi [MESH:D007669] (455)
 Hernia [MESH:D006547] (2825) 
 Hernia, Diaphragmatic [MESH:D006548] (2647)
 Hypertrophy [MESH:D006984] (4476) 
 Cardiomegaly [MESH:D006332] (3802)
 Pathologic Processes [MESH:D010335] (9863) 
 Ischemia [MESH:D007511] (3049)
 Lithiasis [MESH:D020347] (345)
 Nerve Degeneration [MESH:D009410] (4061)
 Arrhythmias, Cardiac [MESH:D001145] (4658) 
 Bradycardia [MESH:D001919] (1899)
 Long QT Syndrome [MESH:D008133] (691)
 Tachycardia [MESH:D013610] (3339)
 Ventricular Fibrillation [MESH:D014693] (624)
 Arrhythmia, Sinus [MESH:D001146] (324) 
 Sick Sinus Syndrome [MESH:D012804] (293)
 Heart Block [MESH:D006327] (571) 
 Sick Sinus Syndrome [MESH:D012804] (293)
 Disease Attributes [MESH:D020969] (3654) 
 Recurrence [MESH:D012008] (830)
 Growth Disorders [MESH:D006130] (2438) 
 Insulin-Like Growth Factor I Deficiency [MESH:C563867] (346)
 Hemorrhage [MESH:D006470] (4451) 
 Hematuria [MESH:D006417] (477)
 Intracranial Hemorrhages [MESH:D020300] (3241) 
 Cerebral Hemorrhage [MESH:D002543] (2872)
 Purpura [MESH:D011693] (475) 
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
 Inflammation [MESH:D007249] (5241) 
 Neurogenic Inflammation [MESH:D020078] (2246)
 Menstruation Disturbances [MESH:D008599] (926) 
 Amenorrhea [MESH:D000568] (817)
 Necrosis [MESH:D009336] (4019) 
 Osteonecrosis [MESH:D010020] (537) 
 Femur Head Necrosis [MESH:D005271] (266)
 Neoplastic Processes [MESH:D009385] (5317) 
 Neoplasm Invasiveness [MESH:D009361] (3388)
 Neoplasm Metastasis [MESH:D009362] (4441)
 Neoplasm Recurrence, Local [MESH:D009364] (1949)
 Postoperative Complications [MESH:D011183] (5311) 
 Graft Occlusion, Vascular [MESH:D006083] (139)
 Reperfusion Injury [MESH:D015427] (4968)
 Signs and Symptoms [MESH:D012816] (10659) 
 Edema [MESH:D004487] (3726)
 Body Temperature Changes [MESH:D001832] (3130) 
 Fever [MESH:D005334] (2856)
 Hypothermia [MESH:D007035] (2075)
 Body Weight [MESH:D001835] (4972) 
 Body Weight Changes [MESH:D001836] (3206) 
 Weight Gain [MESH:D015430] (2595)
 Weight Loss [MESH:D015431] (2512)
 Overweight [MESH:D050177] (4455) 
 Obesity [MESH:D009765] (4454) 
 Proopiomelanocortin Deficiency [MESH:C565726] (200)
 Eye Manifestations [MESH:D005132] (213) 
 Eye Pain [MESH:D058447] (207)
 Neurologic Manifestations [MESH:D009461] (8702) 
 Seizures [MESH:D012640] (4502)
 Sleep Disorders [MESH:D012893] (1301)
 Dyskinesias [MESH:D020820] (3285) 
 Catalepsy [MESH:D002375] (1429)
 Neurobehavioral Manifestations [MESH:D019954] (4706) 
 Memory Disorders [MESH:D008569] (3233) 
 Amnesia [MESH:D000647] (1911)
 Neuromuscular Manifestations [MESH:D020879] (2130) 
 Muscular Atrophy [MESH:D009133] (1234)
 Pain [MESH:D010146] (3869) 
 Headache [MESH:D006261] (1417)
 Paralysis [MESH:D010243] (2298) 
 Facial Paralysis [MESH:D005158] (238)
 Sensation Disorders [MESH:D012678] (5009) 
 Hearing Disorders [MESH:D006311] (2101) 
 Hearing Loss [MESH:D034381] (2066) 
 Hearing Loss, Sensorineural [MESH:D006319] (1227) 
 Insulin-Like Growth Factor I Deficiency [MESH:C563867] (346)
 Somatosensory Disorders [MESH:D020886] (4000) 
 Hyperalgesia [MESH:D006930] (3929)
 Pain [MESH:D010146] (4511) 
 Eye Pain [MESH:D058447] (207)
 Headache [MESH:D006261] (1417)
 Chest Pain [MESH:D002637] (2642) 
 Angina Pectoris [MESH:D000787] (2568) 
 Angina, Unstable [MESH:D000789] (782)
 Signs and Symptoms, Digestive [MESH:D012817] (3095) 
 Constipation [MESH:D003248] (506)
 Nausea [MESH:D009325] (2300)
 Vomiting [MESH:D014839] (1354)
 Signs and Symptoms, Respiratory [MESH:D012818] (2724) 
 Anoxia [MESH:D000860] (1698)
 Skin Manifestations [MESH:D012877] (1250) 
 Purpura [MESH:D011693] (475) 
 Purpura, Schoenlein-Henoch [MESH:D011695] (266)
 Urological Manifestations [MESH:D020924] (3532) 
 Hypercalciuria [MESH:D053565] (330)
 Oliguria [MESH:D009846] (307)
 Proteinuria [MESH:D011507] (3293)
 Virilism [MESH:D014770] (327) 
 Hirsutism [MESH:D006628] (323)
C25. Chemically-Induced Disorders 
C25. Chemically-Induced Disorders
 Substance-Related Disorders [MESH:D019966] (6308) 
 Cocaine-Related Disorders [MESH:D019970] (3054)
 Substance Withdrawal Syndrome [MESH:D013375] (2956)
 Alcohol-Related Disorders [MESH:D019973] (3869) 
 Alcoholism [MESH:D000437] (1519)
 Opioid-Related Disorders [MESH:D009293] (1491) 
 Heroin Dependence [MESH:D006556] (950)
C26. Wounds and Injuries 
C26. Wounds and Injuries
 Wounds and Injuries [MESH:D014947] (5171) 
 Burns [MESH:D002056] (2565)
D04. Polycyclic Compounds 
D04. Polycyclic Compounds
 Polycyclic Compounds [MESH:D011083] (22048) 
 Steroids [MESH:D013256] (6272) 
 Androstanes [MESH:D000731] (757) 
 Androstanols [MESH:D000732] (205) 
 Dihydrotestosterone [MESH:D013196] (48)
D06. Hormones, Hormone Substitutes, and Hormone Antagonists 
D06. Hormones, Hormone Substitutes, and Hormone Antagonists
 Hormones [MESH:D006728] (4254) 
 Gonadal Hormones [MESH:D042341] (1226) 
 Gonadal Steroid Hormones [MESH:D012739] (1172) 
 Testosterone Congeners [MESH:D045165] (359) 
 Dihydrotestosterone [MESH:D013196] (46)
D27. Chemical Actions and Uses 
D27. Chemical Actions and Uses
 Pharmacologic Actions [MESH:D020228] (2566) 
 Molecular Mechanisms of Pharmacological Action [MESH:D045504] (1155) 
 Enzyme Inhibitors [MESH:D004791] (520)
 Physiological Effects of Drugs [MESH:D045505] (1186) 
 Reproductive Control Agents [MESH:D012102] (62) 
 Abortifacient Agents [MESH:D000019] (9) 
 Abortifacient Agents, Steroidal [MESH:D000021] (2)
 Therapeutic Uses [MESH:D045506] (1611) 
 Antineoplastic Agents [MESH:D000970] (319)
 Reproductive Control Agents [MESH:D012102] (62) 
 Abortifacient Agents [MESH:D000019] (9) 
 Abortifacient Agents, Steroidal [MESH:D000021] (2)
E. Analytical, Diagnostic and Therapeutic Techniques and Equipment 
E. Analytical, Diagnostic and Therapeutic Techniques and Equipment
 Diagnosis [MESH:D003933] (1924) 
 Diagnostic Techniques and Procedures [MESH:D019937] (1902) 
 Physical Examination [MESH:D010808] (1041) 
 Body Constitution [MESH:D001824] (450) 
 Body Weights and Measures [MESH:D001837] (448) 
 Body Size [MESH:D049628] (439) 
 Body Weight [MESH:D001835] (433) 
 Overweight [MESH:D050177] (428) 
 Obesity [MESH:D009765] (427) 
 Proopiomelanocortin Deficiency [MESH:C565726] (200)
G. Phenomena and Processes 
G. Phenomena and Processes
 Physiological Phenomena [MESH:D010829] (788) 
 Body Constitution [MESH:D001824] (453) 
 Body Weights and Measures [MESH:D001837] (444) 
 Body Size [MESH:D049628] (438) 
 Body Weight [MESH:D001835] (433) 
 Overweight [MESH:D050177] (428) 
 Obesity [MESH:D009765] (427) 
 Proopiomelanocortin Deficiency [MESH:C565726] (200)