more general categories |
information about this item |
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1. Human Genes |
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1. Human Genes |
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paraoxonase 1 [HGNC:PON1] (115) |
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2. Interaction: Human Genes and Chemicals |
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2. Interaction: Human Genes and Chemicals |
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binding (2423) |
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hydrolysis (14) |
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metabolic processing (485) |
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reaction (624) |
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activity (2549) |
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hydrolysis (6) |
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response to substance (713) |
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hydrolysis (158) |
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C01. Bacterial Infections and Mycoses |
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C01. Bacterial Infections and Mycoses |
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Tuberculosis, Pulmonary [MESH:D014397] (678) |
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C02. Virus Diseases |
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C02. Virus Diseases |
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Meningitis, Aseptic [MESH:D008582] (1305) |
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Meningitis, Aseptic [MESH:D008582] (1305) |
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Influenza, Human [MESH:D007251] (1075) |
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HIV Seropositivity [MESH:D006679] (480) |
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HIV Seropositivity [MESH:D006679] (480) |
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C03. Parasitic Diseases |
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C03. Parasitic Diseases |
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Leishmaniasis, Cutaneous [MESH:D016773] (2359) |
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Leishmaniasis, Cutaneous [MESH:D016773] (2359) |
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C04. Neoplasms |
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C04. Neoplasms |
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Rhabdomyosarcoma [MESH:D012208] (789) |
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Rhabdomyosarcoma [MESH:D012208] (789) |
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Glioblastoma [MESH:D005909] (2554) |
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Neuroblastoma [MESH:D009447] (1420) |
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Adenocarcinoma of lung [MESH:C538231] (1487) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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Glioblastoma [MESH:D005909] (2554) |
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Neuroblastoma [MESH:D009447] (1420) |
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Glioblastoma [MESH:D005909] (2554) |
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Neuroblastoma [MESH:D009447] (1420) |
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Multiple Myeloma [MESH:D009101] (2767) |
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Liver Neoplasms [MESH:D008113] (6048) |
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Pancreatic Neoplasms [MESH:D010190] (3820) |
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Stomach Neoplasms [MESH:D013274] (4942) |
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Colonic Neoplasms [MESH:D003110] (4405) |
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Pancreatic Neoplasms [MESH:D010190] (3820) |
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Brain Neoplasms [MESH:D001932] (2764) |
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Adenocarcinoma of lung [MESH:C538231] (1487) |
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Endometrial Neoplasms [MESH:D016889] (1987) |
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Prostatic Neoplasms [MESH:D011471] (6135) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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C05. Musculoskeletal Diseases |
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C05. Musculoskeletal Diseases |
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Bamforth syndrome [MESH:C537901] (186) |
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Arthritis, Rheumatoid [MESH:D001172] (3603) |
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Muscle Spasticity [MESH:D009128] (187) |
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Muscular Dystrophy, Duchenne [MESH:D020388] (942) |
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Bamforth syndrome [MESH:C537901] (186) |
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Arthritis, Rheumatoid [MESH:D001172] (3603) |
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C06. Digestive System Diseases |
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C06. Digestive System Diseases |
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Liver Cirrhosis, Biliary [MESH:D008105] (1274) |
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Liver Neoplasms [MESH:D008113] (6048) |
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Pancreatic Neoplasms [MESH:D010190] (3820) |
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Stomach Neoplasms [MESH:D013274] (4942) |
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Colonic Neoplasms [MESH:D003110] (4405) |
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Crohn Disease [MESH:D003424] (2585) |
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Stomach Neoplasms [MESH:D013274] (4942) |
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Colonic Neoplasms [MESH:D003110] (4405) |
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Colonic Neoplasms [MESH:D003110] (4405) |
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Crohn Disease [MESH:D003424] (2585) |
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Colonic Neoplasms [MESH:D003110] (4405) |
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Hemorrhoids [MESH:D006484] (166) |
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Stomach Neoplasms [MESH:D013274] (4942) |
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Drug-Induced Liver Injury [MESH:D056486] (4936) |
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Fatty Liver [MESH:D005234] (3584) |
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Liver Neoplasms [MESH:D008113] (6048) |
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Liver Cirrhosis, Biliary [MESH:D008105] (1274) |
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Liver Failure, Acute [MESH:D017114] (2404) |
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Hepatitis, Autoimmune [MESH:D019693] (1982) |
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Liver Cirrhosis, Biliary [MESH:D008105] (1274) |
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Liver Cirrhosis, Experimental [MESH:D008106] (4589) |
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Pancreatic Neoplasms [MESH:D010190] (3820) |
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Pancreatitis [MESH:D010195] (1924) |
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C07. Stomatognathic Diseases |
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C07. Stomatognathic Diseases |
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Bamforth syndrome [MESH:C537901] (186) |
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Behcet Syndrome [MESH:D001528] (1784) |
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Bamforth syndrome [MESH:C537901] (186) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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Bamforth syndrome [MESH:C537901] (186) |
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Bamforth syndrome [MESH:C537901] (186) |
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C08. Respiratory Tract Diseases |
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C08. Respiratory Tract Diseases |
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Not Fully Specified [NFS] (1984) |
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Pleural Diseases [MESH:D010995] (2240) |
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Asthma [MESH:D001249] (4098) |
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Bronchial Hyperreactivity [MESH:D016535] (1357) |
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Hypertension, Pulmonary [MESH:D006976] (2000) |
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Lung Injury [MESH:D055370] (3688) |
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Pneumonia [MESH:D011014] (3482) |
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Pulmonary Fibrosis [MESH:D011658] (3140) |
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Respiratory Distress Syndrome, Adult [MESH:D012128] (864) |
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Tuberculosis, Pulmonary [MESH:D014397] (678) |
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Asthma [MESH:D001249] (3903) |
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Adenocarcinoma of lung [MESH:C538231] (1487) |
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Rhinitis, Allergic, Perennial [MESH:D012221] (625) |
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Respiratory Distress Syndrome, Adult [MESH:D012128] (864) |
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Sleep Apnea Syndromes [MESH:D012891] (570) |
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Asthma [MESH:D001249] (4098) |
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Rhinitis, Allergic, Perennial [MESH:D012221] (625) |
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Influenza, Human [MESH:D007251] (1075) |
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Pneumonia [MESH:D011014] (3482) |
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Tuberculosis, Pulmonary [MESH:D014397] (678) |
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Adenocarcinoma of lung [MESH:C538231] (1487) |
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C09. Otorhinolaryngologic Diseases |
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C09. Otorhinolaryngologic Diseases |
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Rhinitis, Allergic, Perennial [MESH:D012221] (625) |
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C10. Nervous System Diseases |
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C10. Nervous System Diseases |
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Not Fully Specified [NFS] (4027) |
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Neurotoxicity Syndromes [MESH:D020258] (4570) |
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Multiple Sclerosis [MESH:D009103] (1716) |
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Brain Injuries [MESH:D001930] (3429) |
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Brain Neoplasms [MESH:D001932] (2764) |
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Huntington Disease [MESH:D006816] (540) |
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Carotid Artery Diseases [MESH:D002340] (1993) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Huntington Disease [MESH:D006816] (540) |
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Seizures [MESH:D012640] (4502) |
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Status Epilepticus [MESH:D013226] (4014) |
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Epilepsy, Temporal Lobe [MESH:D004833] (1108) |
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Epilepsy, Tonic-Clonic [MESH:D004830] (1042) |
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Meningitis, Aseptic [MESH:D008582] (1305) |
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Meningitis, Aseptic [MESH:D008582] (1305) |
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Meningitis, Aseptic [MESH:D008582] (1305) |
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Huntington Disease [MESH:D006816] (540) |
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Spinal Cord Compression [MESH:D013117] (1800) |
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Amyotrophic Lateral Sclerosis, Sporadic [MESH:C566291] (239) |
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Multiple Sclerosis [MESH:D009103] (1716) |
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Spinal Dysraphism [MESH:D016135] (1025) |
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Brain Neoplasms [MESH:D001932] (2764) |
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Huntington Disease [MESH:D006816] (540) |
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Amyotrophic Lateral Sclerosis, Sporadic [MESH:C566291] (239) |
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Amyotrophic Lateral Sclerosis, Sporadic [MESH:C566291] (239) |
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Pain [MESH:D010146] (3875) |
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Paralysis [MESH:D010243] (2043) |
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Paresis [MESH:D010291] (419) |
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Seizures [MESH:D012640] (4514) |
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Catalepsy [MESH:D002375] (1429) |
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Hyperkinesis [MESH:D006948] (1799) |
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Tremor [MESH:D014202] (840) |
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Memory Disorders [MESH:D008569] (3233) |
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Learning Disorders [MESH:D007859] (2727) |
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Fasciculation [MESH:D005207] (204) |
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Muscle Spasticity [MESH:D009128] (187) |
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Trismus [MESH:D014313] (221) |
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Hyperalgesia [MESH:D006930] (3929) |
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Amyotrophic Lateral Sclerosis, Sporadic [MESH:C566291] (239) |
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Muscular Dystrophy, Duchenne [MESH:D020388] (942) |
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Sleep Apnea Syndromes [MESH:D012891] (570) |
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Brain Injuries [MESH:D001930] (3431) |
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C11. Eye Diseases |
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C11. Eye Diseases |
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Diabetic Retinopathy [MESH:D003930] (1371) |
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Behcet Syndrome [MESH:D001528] (1784) |
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C12. Male Urogenital Diseases |
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C12. Male Urogenital Diseases |
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Prostatic Neoplasms [MESH:D011471] (6135) |
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Infertility, Male [MESH:D007248] (2851) |
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Prostatic Neoplasms [MESH:D011471] (6135) |
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Prostatic Neoplasms [MESH:D011471] (6135) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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Anuria [MESH:D001002] (833) |
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Diabetic Nephropathies [MESH:D003928] (2301) |
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Hyperoxaluria [MESH:D006959] (1498) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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Nephritis, Interstitial [MESH:D009395] (1927) |
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Glomerulonephritis, Membranoproliferative [MESH:D015432] (770) |
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Glomerulonephritis, Membranous [MESH:D015433] (642) |
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Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754) |
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Nephrotic Syndrome [MESH:D009404] (1536) |
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Acute Kidney Injury [MESH:D058186] (4142) |
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Kidney Failure, Chronic [MESH:D007676] (2930) |
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Hemolytic-Uremic Syndrome [MESH:D006463] (2435) |
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Cystitis, Interstitial [MESH:D018856] (264) |
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Anuria [MESH:D001002] (833) |
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Proteinuria [MESH:D011507] (3293) |
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C13. Female Urogenital Diseases and Pregnancy Complications |
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C13. Female Urogenital Diseases and Pregnancy Complications |
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Endometriosis [MESH:D004715] (2461) |
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Endometrial Neoplasms [MESH:D016889] (1984) |
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Endometrial Neoplasms [MESH:D016889] (1989) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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Anuria [MESH:D001002] (833) |
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Diabetic Nephropathies [MESH:D003928] (2301) |
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Hyperoxaluria [MESH:D006959] (1498) |
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Carcinoma, Renal Cell [MESH:D002292] (2975) |
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Nephritis, Interstitial [MESH:D009395] (1927) |
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Glomerulonephritis, Membranoproliferative [MESH:D015432] (770) |
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Glomerulonephritis, Membranous [MESH:D015433] (642) |
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Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754) |
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Nephrotic Syndrome [MESH:D009404] (1536) |
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Acute Kidney Injury [MESH:D058186] (4142) |
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Kidney Failure, Chronic [MESH:D007676] (2930) |
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Hemolytic-Uremic Syndrome [MESH:D006463] (2435) |
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Cystitis, Interstitial [MESH:D018856] (264) |
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Anuria [MESH:D001002] (833) |
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Proteinuria [MESH:D011507] (3293) |
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Abortion, Spontaneous [MESH:D000022] (2780) |
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Prenatal Injuries [MESH:D049188] (1314) |
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Pre-Eclampsia [MESH:D011225] (1435) |
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Obstetric Labor, Premature [MESH:D007752] (1316) |
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C14. Cardiovascular Diseases |
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C14. Cardiovascular Diseases |
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Not Fully Specified [NFS] (2667) |
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Heart Failure [MESH:D006333] (4058) |
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Heart Valve Diseases [MESH:D006349] (3333) |
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Tachycardia [MESH:D013610] (3339) |
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Myocardial Reperfusion Injury [MESH:D015428] (3500) |
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Myocardial Reperfusion Injury [MESH:D015428] (3500) |
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Coronary Artery Disease [MESH:D003324] (2685) |
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Coronary Vasospasm [MESH:D003329] (533) |
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Angioedema [MESH:D000799] (837) |
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Arteritis [MESH:D001167] (1084) |
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Hemorrhoids [MESH:D006484] (166) |
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Hypertension [MESH:D006973] (5655) |
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Hypotension [MESH:D007022] (4045) |
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Atherosclerosis [MESH:D050197] (4188) |
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Coronary Artery Disease [MESH:D003324] (2685) |
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Carotid Artery Diseases [MESH:D002340] (1993) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Infarction, Middle Cerebral Artery [MESH:D020244] (2268) |
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Diabetic Retinopathy [MESH:D003930] (1371) |
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Thrombosis [MESH:D013927] (3101) |
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Multiple Myeloma [MESH:D009101] (2765) |
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Myocardial Reperfusion Injury [MESH:D015428] (3500) |
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Coronary Artery Disease [MESH:D003324] (2685) |
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Coronary Vasospasm [MESH:D003329] (533) |
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Myocardial Reperfusion Injury [MESH:D015428] (3500) |
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Arteritis [MESH:D001167] (1084) |
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Behcet Syndrome [MESH:D001528] (1784) |
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C15. Hemic and Lymphatic Diseases |
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C15. Hemic and Lymphatic Diseases |
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Hemolytic-Uremic Syndrome [MESH:D006463] (2435) |
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Hemolytic-Uremic Syndrome [MESH:D006463] (2435) |
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Hypoalbuminemia [MESH:D034141] (1332) |
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Multiple Myeloma [MESH:D009101] (2765) |
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Plasminogen Activator Inhibitor-1 Deficiency [MESH:C567640] (328) |
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Multiple Myeloma [MESH:D009101] (2765) |
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C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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Bamforth syndrome [MESH:C537901] (186) |
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Bamforth syndrome [MESH:C537901] (186) |
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Spinal Dysraphism [MESH:D016135] (1025) |
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Bamforth syndrome [MESH:C537901] (186) |
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Bamforth syndrome [MESH:C537901] (186) |
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Hyperthyroxinemia, Familial Dysalbuminemic [MESH:D050010] (478) |
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Muscular Dystrophy, Duchenne [MESH:D020388] (942) |
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Huntington Disease [MESH:D006816] (540) |
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Butyrylcholinesterase deficiency [MESH:C537417] (176) |
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Hyperhomocysteinemia [MESH:D020138] (1724) |
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Hyperlipoproteinemia Type II [MESH:D006938] (707) |
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Muscular Dystrophy, Duchenne [MESH:D020388] (942) |
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Dermatitis, Atopic [MESH:D003876] (2052) |
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C17. Skin and Connective Tissue Diseases |
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C17. Skin and Connective Tissue Diseases |
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Keloid [MESH:D007627] (1111) |
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Arthritis, Rheumatoid [MESH:D001172] (3603) |
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Dermatitis, Atopic [MESH:D003876] (2052) |
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Serum Sickness [MESH:D012713] (484) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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Bamforth syndrome [MESH:C537901] (186) |
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Dermatitis, Atopic [MESH:D003876] (2052) |
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Dermatitis, Atopic [MESH:D003876] (2052) |
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Leishmaniasis, Cutaneous [MESH:D016773] (2359) |
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Behcet Syndrome [MESH:D001528] (1784) |
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Angioedema [MESH:D000799] (837) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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C18. Nutritional and Metabolic Diseases |
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C18. Nutritional and Metabolic Diseases |
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Metabolic Syndrome X [MESH:D024821] (2151) |
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Calcinosis [MESH:D002114] (2989) |
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Diabetes Mellitus, Experimental [MESH:D003921] (4771) |
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Maturity-Onset Diabetes of the Young, Type 8, with Exocrine Dysfunction [MESH:C565225] (56) |
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Metabolic Syndrome X [MESH:D024821] (2151) |
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Hypercholesterolemia [MESH:D006937] (1404) |
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Hyperlipoproteinemia Type II [MESH:D006938] (707) |
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Hyperhomocysteinemia [MESH:D020138] (1716) |
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Butyrylcholinesterase deficiency [MESH:C537417] (176) |
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Hyperhomocysteinemia [MESH:D020138] (1724) |
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Hyperlipoproteinemia Type II [MESH:D006938] (707) |
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Amyotrophic Lateral Sclerosis, Sporadic [MESH:C566291] (239) |
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Hyperhomocysteinemia [MESH:D020138] (1716) |
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Obesity [MESH:D009765] (4462) |
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C19. Endocrine System Diseases |
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C19. Endocrine System Diseases |
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Diabetes Mellitus, Experimental [MESH:D003921] (4771) |
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Diabetic Nephropathies [MESH:D003928] (2301) |
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Diabetic Retinopathy [MESH:D003930] (1371) |
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Maturity-Onset Diabetes of the Young, Type 8, with Exocrine Dysfunction [MESH:C565225] (56) |
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Pancreatic Neoplasms [MESH:D010190] (3820) |
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Hyperthyroidism [MESH:D006980] (1191) |
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Hyperthyroxinemia, Familial Dysalbuminemic [MESH:D050010] (478) |
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Bamforth syndrome [MESH:C537901] (186) |
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C20. Immune System Diseases |
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C20. Immune System Diseases |
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Glomerulonephritis, Membranoproliferative [MESH:D015432] (770) |
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Arthritis, Rheumatoid [MESH:D001172] (3601) |
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Glomerulonephritis, Membranous [MESH:D015433] (642) |
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Hepatitis, Autoimmune [MESH:D019693] (1982) |
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Multiple Sclerosis [MESH:D009103] (1716) |
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Hypersensitivity, Delayed [MESH:D006968] (3408) |
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Serum Sickness [MESH:D012713] (484) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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Dermatitis, Atopic [MESH:D003876] (2052) |
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Asthma [MESH:D001249] (3914) |
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Rhinitis, Allergic, Perennial [MESH:D012221] (625) |
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Angioedema [MESH:D000799] (837) |
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Serum Sickness [MESH:D012713] (484) |
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HIV Seropositivity [MESH:D006679] (480) |
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Multiple Myeloma [MESH:D009101] (2767) |
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Multiple Myeloma [MESH:D009101] (2765) |
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C22. Animal Diseases |
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C22. Animal Diseases |
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Disease Models, Animal [MESH:D004195] (2058) |
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C23. Pathological Conditions, Signs and Symptoms |
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C23. Pathological Conditions, Signs and Symptoms |
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Death [MESH:D003643] (1328) |
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Inflammation [MESH:D007249] (5241) |
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Nerve Degeneration [MESH:D009410] (4061) |
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Tachycardia [MESH:D013610] (3339) |
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Keloid [MESH:D007627] (1110) |
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Myocardial Reperfusion Injury [MESH:D015428] (3500) |
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Pain [MESH:D010146] (4511) |
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Hypothermia [MESH:D007035] (2075) |
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Birth Weight [MESH:D001724] (377) |
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Weight Gain [MESH:D015430] (2595) |
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Obesity [MESH:D009765] (4454) |
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Pain [MESH:D010146] (3869) |
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Paralysis [MESH:D010243] (2298) |
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Paresis [MESH:D010291] (419) |
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Seizures [MESH:D012640] (4502) |
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Catalepsy [MESH:D002375] (1429) |
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Hyperkinesis [MESH:D006948] (1799) |
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Tremor [MESH:D014202] (840) |
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Memory Disorders [MESH:D008569] (3233) |
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Learning Disorders [MESH:D007859] (2727) |
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Fasciculation [MESH:D005207] (204) |
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Muscle Spasticity [MESH:D009128] (187) |
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Trismus [MESH:D014313] (221) |
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Hyperalgesia [MESH:D006930] (3929) |
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Constipation [MESH:D003248] (506) |
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Apnea [MESH:D001049] (415) |
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Proteinuria [MESH:D011507] (3293) |
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C24. Occupational Diseases |
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C24. Occupational Diseases |
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Agricultural Workers' Diseases [MESH:D000382] (193) |
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Persian Gulf Syndrome [MESH:D018923] (166) |
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C25. Chemically-Induced Disorders |
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C25. Chemically-Induced Disorders |
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Drug-Induced Liver Injury [MESH:D056486] (4936) |
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Serum Sickness [MESH:D012713] (484) |
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Stevens-Johnson Syndrome [MESH:D013262] (1163) |
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Drug-Induced Liver Injury [MESH:D056486] (4936) |
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Neurotoxicity Syndromes [MESH:D020258] (3323) |
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Organophosphate Poisoning [MESH:D062025] (497) |
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Amphetamine-Related Disorders [MESH:D019969] (2858) |
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Cocaine-Related Disorders [MESH:D019970] (3054) |
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Marijuana Abuse [MESH:D002189] (1132) |
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Substance Withdrawal Syndrome [MESH:D013375] (2956) |
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C26. Wounds and Injuries |
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C26. Wounds and Injuries |
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Brain Injuries [MESH:D001930] (3431) |
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Spinal Cord Compression [MESH:D013117] (1800) |
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Lung Injury [MESH:D055370] (1814) |
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Brain Injuries [MESH:D001930] (3431) |
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D02. Organic Chemicals |
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D02. Organic Chemicals |
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Organophosphorus Compounds [MESH:D009943] (2593) |
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