| more general categories |
information about this item |
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| 10. Noble Prize |
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10. Noble Prize |
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Physiology or Medicine (216) |
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| 11. Award Year |
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11. Award Year |
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1958 (9) |
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| 12. Winner Type |
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12. Winner Type |
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Person (904) |
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| 13. Gender |
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13. Gender |
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Male (853) |
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| 14. Birth Year |
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14. Birth Year |
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1909 (2) |
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| 15. Place of Birth |
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15. Place of Birth |
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Boulder (1) |
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| 16. Death Year |
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16. Death Year |
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1975 (7) |
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| 17. Place of Death |
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17. Place of Death |
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New York City (24) |
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| 19. Given Name |
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19. Given Name |
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E (55) |
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| 20. Family Name |
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20. Family Name |
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T (34) |
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| 21. Shared Given Name |
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21. Shared Given Name |
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Edward (8) |
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| 23. Religion |
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23. Religion |
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Source data not available (465) |
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| 24. Age at Award Time |
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24. Age at Award Time |
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50 - 59 (231) |
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| 32. Occupations |
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32. Occupations |
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Biological Scientists (181) |
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| 34. Citizens |
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34. Citizens |
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United States (307) |
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| 37. Worked for College or University |
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37. Worked for College or University |
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Rockefeller University (17) |
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| 42. Affilliation with College or University |
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42. Affilliation with College or University |
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Short-term academic staff (3) |
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Alumni (34) |
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Alumni (13) |
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Long-term academic staff (28) |
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Long-term academic staff (26) |
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Long-term academic staff (46) |
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Short-term academic staff (35) |
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| 44. Memberships |
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44. Memberships |
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American Academy of Arts and Sciences (531) |
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American Philosophical Society (126) |
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National Academy of Sciences (334) |
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| complete name: |
Edward Lawrie Tatum |
| nobel prize: |
medicine |
| award year: |
1958 |
| together with: |
Joshua Lederberg |
| together with: |
George Beadle |
| prize share: |
Prize share: 1/2 |
| rational: |
The Nobel Prize in Physiology or Medicine 1958 was divided, one half jointly to George Wells Beadle and Edward Lawrie Tatum "for their discovery that genes act by regulating definite chemical events" and the other half to Joshua Lederberg "for his discoveries concerning genetic recombination and the organization of the genetic material of bacteria." |
| biography: |
Biography |
| laureate facts: |
Facts |
| laureate lecture: |
Lecture |
| given name: |
Edward |
| family name: |
Tatum |
| occupation: |
biochemist |
| occupation: |
geneticist |
| work location: |
Stanford University, Stanford, United States of America |
| description: |
Edward Lawrie Tatum was an American geneticist. He shared half of the Nobel Prize in Physiology or Medicine in 1958 with George Beadle for showing that genes control individual steps in metabolism. The other half of that year's award went to Joshua Lederberg. Beadle and Tatum's key experiments involved exposing the bread mold Neurospora crassa to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways. These experiments, published in 1941, led them to propose a direct link between genes and enzymatic reactions, known as the "one gene, one enzyme" hypothesis. Tatum went on to study genetics in bacteria. An active area of research in his laboratory was to understand the basis of Tryptophan biosynthesis in Escherichia coli. Later, Tatum and his student Joshua Lederberg showed that E. coli could share genetic information through recombination. Tatum was born in Boulder, Colorado. He attended college at the University of Chicago and received his PhD in biochemistry from the University of Wisconsin-Madison in 1934. Starting in 1937, he worked at Stanford University, where he began his collaboration with Beadle. He then moved to Yale University in 1945 where he mentored Lederberg. He returned to Stanford in 1948 and then joined the faculty of Rockefeller Institute in 1957. A heavy cigarette smoker, he died in New York City of heart failure complicated by chronic emphysema. |
| image copyright: |
Photo from the Nobel Foundation archive. |
| image citation: |
The Nobel Prize in Physiology or Medicine 1958. NobelPrize.org. Nobel Media AB 2018. <https://www.nobelprize.org/prizes/medicine/1958/summary/> |
| date birth: |
1909 |
| date death: |
1975 |
| usual name: |
Edward Tatum |
