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information about this item |
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| 10. Noble Prize |
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10. Noble Prize |
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Physiology or Medicine (216) |
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| 11. Award Year |
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11. Award Year |
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1984 (9) |
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| 12. Winner Type |
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12. Winner Type |
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Person (904) |
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| 13. Gender |
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13. Gender |
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Male (853) |
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| 14. Birth Year |
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14. Birth Year |
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1911 (17) |
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| 15. Place of Birth |
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15. Place of Birth |
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London (16) |
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| 16. Death Year |
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16. Death Year |
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1994 (10) |
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| 17. Place of Death |
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17. Place of Death |
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Castillon-du-Gard (1) |
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| 19. Given Name |
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19. Given Name |
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N (18) |
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| 20. Family Name |
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20. Family Name |
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J (10) |
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| 21. Shared Given Name |
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21. Shared Given Name |
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Niels (3) |
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| 23. Religion |
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23. Religion |
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Source data not available (465) |
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| 24. Age at Award Time |
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24. Age at Award Time |
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74 (21) |
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| 32. Occupations |
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32. Occupations |
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Biological Scientists (181) |
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| 34. Citizens |
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34. Citizens |
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Denmark (12) |
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| 39. Worked for Medical Organization |
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39. Worked for Medical Organization |
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Basel Institute for Immunology (2) |
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| 42. Affilliation with College or University |
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42. Affilliation with College or University |
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Long-term academic staff (4) |
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Long-term academic staff (2) |
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Long-term academic staff (3) |
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Short-term academic staff (40) |
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| 44. Memberships |
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44. Memberships |
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American Academy of Arts and Sciences (531) |
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American Philosophical Society (126) |
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French Academy of Sciences (89) |
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National Academy of Sciences (334) |
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Royal Danish Academy of Sciences and Letters (13) |
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Royal Society (294) |
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| 45. Other Awards |
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45. Other Awards |
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Fellow of the Royal Society (101) |
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Gairdner Foundation International Award (89) |
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Marcel Benoist Prize (10) |
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Paul Ehrlich and Ludwig Darmstaedter Prize (21) |
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| complete name: |
Niels Kaj Jerne |
| nobel prize: |
medicine |
| award year: |
1984 |
| together with: |
Georges J. F. Köhler |
| together with: |
César Milstein |
| prize share: |
Prize share: 1/3 |
| rational: |
The Nobel Prize in Physiology or Medicine 1984 was awarded jointly to Niels K. Jerne, Georges J.F. Köhler and César Milstein "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies." |
| biography: |
Biography |
| laureate facts: |
Facts |
| laureate lecture: |
Lecture |
| given name: |
Niels |
| family name: |
Jerne |
| occupation: |
physician |
| occupation: |
immunologist |
| work location: |
University of Pittsburgh, 4200 Fifth Avenue, Pittsburgh, PA, 15260, United States of America |
| description: |
Niels Kaj Jerne was a Danish immunologist. He shared the Nobel Prize in Physiology or Medicine in 1984 with Georges J. F. Köhler and César Milstein "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies". Jerne is known for three significant ideas. Firstly, instead of the body producing antibodies in response to an antigen, Jerne postulated that the immune system already has the specific antibodies it needs to fight antigens. Secondly, it was known that the immune system learns to be tolerant to the individual's own self. Jerne postulated that this learning takes place in the thymus. Thirdly, it was known that T cells and B cells communicate with each other. Jerne's network theory proposed that the active sites of antibodies are attracted to both specific antigens (idiotypes) and to other antibodies that bind to the same site. The antibodies are in balance, until an antigen disturbs the balance, stimulating an immune reaction. |
| image copyright: |
Photo from the Nobel Foundation archive. |
| image citation: |
The Nobel Prize in Physiology or Medicine 1984. NobelPrize.org. Nobel Media AB 2018. <https://www.nobelprize.org/prizes/medicine/1984/summary/> |
| date birth: |
1911 |
| date death: |
1994 |
| usual name: |
Niels Jerne |
