| more general categories |
information about this item |
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| 10. Noble Prize |
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10. Noble Prize |
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Physiology or Medicine (216) |
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| 11. Award Year |
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11. Award Year |
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1965 (9) |
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| 12. Winner Type |
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12. Winner Type |
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Person (904) |
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| 13. Gender |
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13. Gender |
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Male (853) |
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| 14. Birth Year |
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14. Birth Year |
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1910 (10) |
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| 15. Place of Birth |
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15. Place of Birth |
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Paris (22) |
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| 16. Death Year |
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16. Death Year |
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1976 (8) |
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| 17. Place of Death |
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17. Place of Death |
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Cannes (1) |
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| 19. Given Name |
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19. Given Name |
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J (95) |
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| 20. Family Name |
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20. Family Name |
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M (84) |
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| 21. Shared Given Name |
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21. Shared Given Name |
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Jacques (2) |
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| 23. Religion |
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23. Religion |
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Atheism (75) |
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| 24. Age at Award Time |
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24. Age at Award Time |
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56 (23) |
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| 32. Occupations |
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32. Occupations |
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Biological Scientists (181) |
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| 34. Citizens |
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34. Citizens |
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France (60) |
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| 37. Worked for College or University |
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37. Worked for College or University |
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Institut Pasteur (6) |
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| 42. Affilliation with College or University |
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42. Affilliation with College or University |
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Long-term academic staff (9) |
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Alumni (42) |
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Long-term academic staff (21) |
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Short-term academic staff (40) |
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| 44. Memberships |
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44. Memberships |
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Accademia Nazionale delle Scienze detta dei XL (36) |
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American Academy of Arts and Sciences (531) |
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German Academy of Sciences Leopoldina (179) |
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Royal Society (294) |
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Royal Swedish Academy of Sciences (111) |
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| 45. Other Awards |
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45. Other Awards |
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Carus medal (8) |
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Croix de guerre 1939-1945 (2) |
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Grand Prix Charles-Leopold Mayer (14) |
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Knight of the French Order of Academic Palms (2) |
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Leeuwenhoek Lecture (6) |
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Marjory Stephenson Prize (4) |
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Médaille de la Résistance (2) |
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Officer of the Legion of Honour (26) |
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| complete name: |
Jacques Monod |
| nobel prize: |
medicine |
| award year: |
1965 |
| together with: |
François Jacob |
| together with: |
André Lwoff |
| prize share: |
Prize share: 1/3 |
| rational: |
The Nobel Prize in Physiology or Medicine 1965 was awarded jointly to François Jacob, André Lwoff and Jacques Monod "for their discoveries concerning genetic control of enzyme and virus synthesis." |
| biography: |
Biography |
| laureate facts: |
Facts |
| laureate lecture: |
Lecture |
| given name: |
Jacques |
| family name: |
Monod |
| occupation: |
physician |
| occupation: |
biologist |
| occupation: |
biochemist |
| occupation: |
geneticist |
| occupation: |
French Resistance fighter |
| field of work: |
biology |
| work location: |
Collège de France, Paris, Sorbonne, France |
| notable work: |
Chance and Necessity |
| description: |
Jacques Monod was a French biochemist, He won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and Andre Lwoff "for their discoveries concerning genetic control of enzyme and virus synthesis". Monod (along with François Jacob) became famous for his work on the E. coli lac operon, which encodes proteins necessary for the transport and breakdown of the sugar lactose (lac). From their own work and the work of others, he and Jacob came up with a model for how the levels of some proteins in a cell are controlled. In their model, the manufacture of proteins, such as the ones encoded within the lac (lactose) operon, is prevented when a repressor, encoded by a regulatory gene, binds to its operator, a specific site on the DNA next to the genes encoding the proteins. (It is now known that repressor bound to the operator physically blocks RNA polymerase from binding to the promoter, the site where transcription of the adjacent genes begins.) Study of the control of expression of genes in the lac operon provided the first example of a transcriptional regulation system. Monod also suggested the existence of mRNA molecules that link the information encoded in DNA and proteins. He is widely regarded as one of the founders of molecular biology. Monod's interest in the lac operon originated from his doctoral dissertation, for which he studied the growth of bacteria in culture media containing two sugars. |
| image copyright: |
Photo from the Nobel Foundation archive. |
| image citation: |
The Nobel Prize in Physiology or Medicine 1965. NobelPrize.org. Nobel Media AB 2018. <https://www.nobelprize.org/prizes/medicine/1965/summary/> |
| date birth: |
1910 |
| date death: |
1976 |
| usual name: |
Jacques Monod |
