| more general categories |
information about this item |
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| 10. Noble Prize |
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10. Noble Prize |
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Physiology or Medicine (216) |
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| 11. Award Year |
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11. Award Year |
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2011 (13) |
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| 12. Winner Type |
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12. Winner Type |
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Person (904) |
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| 13. Gender |
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13. Gender |
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Male (853) |
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| 14. Birth Year |
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14. Birth Year |
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1941 (16) |
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| 15. Place of Birth |
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15. Place of Birth |
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Echternach (1) |
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| 18. Living Winners |
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18. Living Winners |
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Alive (292) |
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| 19. Given Name |
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19. Given Name |
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J (95) |
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| 20. Family Name |
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20. Family Name |
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H (72) |
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| 21. Shared Given Name |
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21. Shared Given Name |
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Jules (2) |
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| 22. Shared Family Name |
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22. Shared Family Name |
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Hoffmann (2) |
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| 23. Religion |
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23. Religion |
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Source data not available (465) |
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| 24. Age at Award Time |
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24. Age at Award Time |
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71 (22) |
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| 32. Occupations |
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32. Occupations |
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Biological Scientists (181) |
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| 34. Citizens |
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34. Citizens |
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France (60) |
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| 37. Worked for College or University |
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37. Worked for College or University |
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Université de Strasbourg (5) |
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| 42. Affilliation with College or University |
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42. Affilliation with College or University |
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Short-term academic staff (1) |
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Alumni (12) |
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Long-term academic staff (8) |
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| 44. Memberships |
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44. Memberships |
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Academia Europaea (55) |
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Académie française (7) |
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American Academy of Arts and Sciences (531) |
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French Academy of Sciences (89) |
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German Academy of Sciences Leopoldina (179) |
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National Academy of Sciences (334) |
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Russian Academy of Sciences (144) |
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| 45. Other Awards |
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45. Other Awards |
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Balzan Prize (7) |
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CNRS Gold medal (7) |
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Gairdner Foundation International Award (89) |
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Gay-Lussac-Humboldt-Prize (4) |
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Keio Medical Science Prize (8) |
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Legion of Honour (20) |
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Officer of the Legion of Honour (26) |
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Robert Koch Prize (11) |
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Rosenstiel Award (36) |
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Shaw Prize (7) |
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William B. Coley Award (9) |
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| complete name: |
Jules Hoffmann |
| nobel prize: |
medicine |
| award year: |
2011 |
| together with: |
Bruce Beutler |
| together with: |
Ralph Steinman |
| prize share: |
Prize share: 1/2 |
| rational: |
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann "for their discoveries concerning the activation of innate immunity" and the other half to Ralph M. Steinman "for his discovery of the dendritic cell and its role in adaptive immunity." |
| biography: |
Biography |
| laureate facts: |
Facts |
| laureate lecture: |
Lecture |
| given name: |
Jules |
| family name: |
Hoffmann |
| occupation: |
physician |
| occupation: |
biologist |
| occupation: |
university teacher |
| occupation: |
immunologist |
| field of work: |
cell biology |
| field of work: |
immunology |
| work location: |
French Academy of Sciences, Paris, France |
| description: |
Jules Hoffmann is a Luxembourg-born French biologist. During his youth, growing up in Luxembourg, he developed a strong interest in insects under the influence of his father, Jos Hoffmann. This eventually resulted in the younger Hoffmann's dedication to the field of biology using insects as model organisms. He currently holds a faculty position at the University of Strasbourg. He is a research director and member of the board of administrators of the National Center of Scientific Research (CNRS) in Strasbourg, France. He was elected to the positions of Vice-President (2005-2006) and President (2007-2008) of the French Academy of Sciences. Hoffmann and Bruce Beutler were jointly awarded a half share of the 2011 Nobel Prize in Physiology or Medicine for "their discoveries concerning the activation of innate immunity,". [More specifically,the work showing increased Drosomycin expression following activation of Toll pathway in microbial infection.] Hoffmann and Lemaitre discovered the function of the fruit fly Toll gene in innate immunity. Its mammalian homologs, the Toll-like receptors, were discovered by Beutler. Toll-like receptors identify constituents of other organisms like fungi and bacteria, and trigger an immune response, explaining, for example, how septic shock can be triggered by bacterial remains. |
| image copyright: |
Photo: The Rockefeller University |
| image citation: |
The Nobel Prize in Physiology or Medicine 2011. NobelPrize.org. Nobel Media AB 2018. <https://www.nobelprize.org/prizes/medicine/2011/summary/> |
| date birth: |
1941 |
| usual name: |
Jules Hoffmann |
