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Martin Evans
1941-
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complete name  Sir Martin John Evans
nobel prize  medicine
award year  2007
together with  Mario Capecchi
together with  Oliver Smithies
prize share  Prize share: 1/3
rational  The Nobel Prize in Physiology or Medicine 2007 was awarded jointly to Mario R. Capecchi, Sir Martin J. Evans and Oliver Smithies "for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells."
biography  Biography
laureate facts  Facts
laureate lecture  Lecture
birth name  Martin John Evans
given name  Martin
family name  Evans
occupation  university teacher
occupation  geneticist
field of work  developmental biology
work location  University College London, UCL Main Building, London, United Kingdom
description  Sir Martin John Evans is an English biologist who, with Matthew Kaufman, was the first to culture mice embryonic stem cells and cultivate them in a laboratory in 1981. He is also known, along with Mario Capecchi and Oliver Smithies, for his work in the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic stem cells to create specific gene modifications in mice. In 2007, the three shared the Nobel Prize in Physiology or Medicine in recognition of their discovery and contribution to the efforts to develop new treatments for illnesses in humans. He won a major scholarship to Christ's College, Cambridge at a time when advances in genetics were occurring there and became interested in biology and biochemistry. He then went to University College London where he learned laboratory skills supervised by Elizabeth Deuchar. In 1978, he moved to the Department of Genetics, at the University of Cambridge, and in 1980 began his collaboration with Matthew Kaufman. They explored the method of using blastocysts for the isolation of embryonic stem cells. After Kaufman left, Evans continued his work, upgrading his laboratory skills to the newest technologies, isolated the embryonic stem cell of the early mouse embryo and established it in a cell culture. He genetically modified and implanted it into adult female mice with the intent of creating genetically modified offspring, work for which he was awarded the Nobel Prize in 2007. Today, genetically modified mice are considered vital for medical research.
image copyright  © The Nobel Foundation. Photo: U. Montan
image citation  The Nobel Prize in Physiology or Medicine 2007. NobelPrize.org. Nobel Media AB 2018. <https://www.nobelprize.org/prizes/medicine/2007/summary/>
date birth  1941
usual name  Martin Evans