1. Human Genes

1-acylglycerol-3-phosphate O-acyltransferases [HGNC:AGPAT] (26) 5-HT (serotonin) receptors [HGNC:HTR] (146) 7TM orphan receptors [HGNC:O7TM] (3) A-kinase anchor proteins [HGNC:AKAP] (99) Abhydrolase domain containing [HGNC:ABHD] (24) Acetylcholine receptors, nicotinic [HGNC:CHRN] (130) Acid-sensing (proton-gated) ion channels [HGNC:ASIC] (2) Actin related protein 2/3 complex subunits [HGNC:ARPC] (15) Acyl-CoA synthetase family [HGNC:ACS] (59) Acyl-CoA thioesterases [HGNC:ACOT] (25) ADAM metallopeptidase domain containing [HGNC:ADAM] (44) ADAM metallopeptidases with thrombospondin type 1 motif [HGNC:ADAMTS] (53) more...

2. Interaction: Human Genes and Chemicals

Affects (3990) Decreases (5154) Increases (5571)

3. Bioactivity

Hydrolases. [EC 3.-.-.-] (5244) Isomerases. [EC 5.-.-.-] (283) Ligases. [EC 6.-.-.-] (8931) Lyases. [EC 4.-.-.-] (334) Oxidoreductases. [EC 1.-.-.-] (1989) Transferases. [EC 2.-.-.-] (3280) Z. Exceptions (426)

4. Semantic Terms

Entity [STY:T071] (48056) Event [STY:T051] (3319)

A. Anatomy

Animal Structures [MESH:D000825] (65) Bacterial Structures [MESH:D056226] (58) Body Regions [MESH:D001829] (867) Cardiovascular System [MESH:D002319] (1086) Cells [MESH:D002477] (1885) Digestive System [MESH:D004064] (421) Embryonic Structures [MESH:D004628] (139) Endocrine System [MESH:D004703] (206) Fluids and Secretions [MESH:D005441] (77) Fungal Structures [MESH:D056229] (10) Hemic and Immune Systems [MESH:D006424] (272) Integumentary System [MESH:D034582] (104) more...

B. Organisms

Archaea [MESH:D001105] (62) Bacteria [MESH:D001419] (840) Eukaryota [MESH:D056890] (2378) Organism Forms [MESH:D056891] (37) Viruses [MESH:D014780] (542)

C01. Bacterial Infections and Mycoses

Bacterial Infections [MESH:D001424] (3716) Brain Abscess [MESH:D001922] (15) Central Nervous System Infections [MESH:D002494] (12) Infection [MESH:D007239] (4109) Mycoses [MESH:D009181] (385) Zoonoses [MESH:D015047] (1)

C02. Virus Diseases

Virus Diseases [MESH:D014777] (4544)

C03. Parasitic Diseases

Parasitic Diseases [MESH:D010272] (3828)

C04. Neoplasms

Neoplasms [MESH:D009369] (10293)

C05. Musculoskeletal Diseases

Musculoskeletal Diseases [MESH:D009140] (8705)

C06. Digestive System Diseases

Digestive System Diseases [MESH:D004066] (9461)

C07. Stomatognathic Diseases

Stomatognathic Diseases [MESH:D009057] (5348)

C08. Respiratory Tract Diseases

Respiratory Tract Diseases [MESH:D012140] (7881) Z. Exceptions (1984)

C09. Otorhinolaryngologic Diseases

Otorhinolaryngologic Diseases [MESH:D010038] (3827)

C10. Nervous System Diseases

Nervous System Diseases [MESH:D009422] (13325) Z. Exceptions (4027)

C11. Eye Diseases

Eye Diseases [MESH:D005128] (6245) Z. Exceptions (245)

C12. Male Urogenital Diseases

Male Urogenital Diseases [MESH:D052801] (8891) Z. Exceptions (10)

C13. Female Urogenital Diseases and Pregnancy Complications

Female Urogenital Diseases [MESH:D052776] (8724) Pregnancy Complications [MESH:D011248] (4768) Z. Exceptions (1116)

C14. Cardiovascular Diseases

Cardiovascular Diseases [MESH:D002318] (10123) Z. Exceptions (2667)

C15. Hemic and Lymphatic Diseases

Hematologic Diseases [MESH:D006402] (6174) Lymphatic Diseases [MESH:D008206] (5167) Z. Exceptions (453)

C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152) Z. Exceptions (5)

C17. Skin and Connective Tissue Diseases

Connective Tissue Diseases [MESH:D003240] (4490) Skin Diseases [MESH:D012871] (8774) Z. Exceptions (1)

C18. Nutritional and Metabolic Diseases

Metabolic Diseases [MESH:D008659] (9025) Nutrition Disorders [MESH:D009748] (4945) Z. Exceptions (817)

C19. Endocrine System Diseases

Endocrine System Diseases [MESH:D004700] (8062) Z. Exceptions (123)

C20. Immune System Diseases

Immune System Diseases [MESH:D007154] (7674) Z. Exceptions (350)

C21. Disorders of Environmental Origin

Disorders of Environmental Origin [MESH:D007280] (16)

C22. Animal Diseases

Animal Diseases [MESH:D000820] (3656)

C23. Pathological Conditions, Signs and Symptoms

Pathologic Processes [MESH:D010335] (9863) Pathological Conditions, Anatomical [MESH:D020763] (6074) Signs and Symptoms [MESH:D012816] (10659)

C24. Occupational Diseases

Occupational Diseases [MESH:D009784] (3402) Z. Exceptions (1530)

C25. Chemically-Induced Disorders

Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839) Poisoning [MESH:D011041] (6703) Substance-Related Disorders [MESH:D019966] (6308)

C26. Wounds and Injuries

Wounds and Injuries [MESH:D014947] (5171) Z. Exceptions (2454)

D01. Inorganic Chemicals

Acids [MESH:D000143] (789) Alkalies [MESH:D000468] (142) Aluminum Compounds [MESH:D017607] (202) Arsenicals [MESH:D001152] (159) Barium Compounds [MESH:D017609] (31) Boron Compounds [MESH:D001896] (534) Bromine Compounds [MESH:D017605] (36) Cadmium Compounds [MESH:D019187] (14) Calcium Compounds [MESH:D017610] (235) Carbon Compounds, Inorganic [MESH:D017554] (143) Chlorine Compounds [MESH:D017606] (460) Chromium Compounds [MESH:D017608] (58) more...

D02. Organic Chemicals

Organic Chemicals [MESH:D009930] (75987) Z. Exceptions (548)

D03. Heterocyclic Compounds

Heterocyclic Compounds [MESH:D006571] (56330) Z. Exceptions (172)

D04. Polycyclic Compounds

Polycyclic Compounds [MESH:D011083] (22048) Z. Exceptions (153)

D05. Macromolecular Substances

Macromolecular Substances [MESH:D046911] (6105) Z. Exceptions (1)

D06. Hormones, Hormone Substitutes, and Hormone Antagonists

Hormone Antagonists [MESH:D006727] (14) Hormones [MESH:D006728] (4254)

D08. Enzymes and Coenzymes

Coenzymes [MESH:D003067] (1063) Cytochromes [MESH:D003580] (649) Enzyme Precursors [MESH:D004792] (160) Enzymes [MESH:D004798] (22802) Z. Exceptions (3)

D09. Carbohydrates

Carbohydrates [MESH:D002241] (15391) Z. Exceptions (15)

D10. Lipids

Lipids [MESH:D008055] (8597) Z. Exceptions (100)

D12. Amino Acids, Peptides, and Proteins

Amino Acids [MESH:D000596] (5544) Peptides [MESH:D010455] (20561) Proteins [MESH:D011506] (65761) Z. Exceptions (185)

D13. Nucleic Acids, Nucleotides, and Nucleosides

Antisense Elements (Genetics) [MESH:D016375] (605) Nucleic Acid Precursors [MESH:D009694] (7) Nucleic Acids [MESH:D009696] (1040) Nucleosides [MESH:D009705] (2984) Nucleotides [MESH:D009711] (2807)

D20. Complex Mixtures

Complex Mixtures [MESH:D045424] (3773) Z. Exceptions (43)

D23. Biological Factors

Biological Factors [MESH:D001685] (12003) Z. Exceptions (29)

D25. Biomedical and Dental Materials

Alloys [MESH:D000497] (92) Biocompatible Materials [MESH:D001672] (18) Cariogenic Agents [MESH:D002326] (1) Cariostatic Agents [MESH:D002327] (53) Ceramics [MESH:D002516] (99) Dental Materials [MESH:D003764] (1044) Dentifrices [MESH:D003802] (7) Membranes, Artificial [MESH:D008567] (4) Mouthwashes [MESH:D009067] (5) Pharmaceutical Preparations, Dental [MESH:D053210] (1) Polymers [MESH:D011108] (3436) Root Canal Irrigants [MESH:D012388] (1) more...

D26. Pharmaceutical Preparations

Controlled Substances [MESH:D061891] (1) Counterfeit Drugs [MESH:D058110] (1) Designer Drugs [MESH:D015198] (1) Dosage Forms [MESH:D004304] (60) Drug Combinations [MESH:D004338] (1656) Drugs, Chinese Herbal [MESH:D004365] (892) Drugs, Essential [MESH:D018954] (1) Drugs, Generic [MESH:D016568] (1) Drugs, Investigational [MESH:D015507] (1) Materia Medica [MESH:D008419] (7) Medical Marijuana [MESH:D064086] (1) Nonprescription Drugs [MESH:D004366] (2) more...

D27. Chemical Actions and Uses

Pharmacologic Actions [MESH:D020228] (2566) Specialty Uses of Chemicals [MESH:D020313] (713) Toxic Actions [MESH:D004786] (206)

E. Analytical, Diagnostic and Therapeutic Techniques and Equipment

Anesthesia and Analgesia [MESH:D000760] (40) Dentistry [MESH:D003813] (206) Diagnosis [MESH:D003933] (1924) Equipment and Supplies [MESH:D004864] (327) Investigative Techniques [MESH:D008919] (1027) Surgical Procedures, Operative [MESH:D013514] (509) Therapeutics [MESH:D013812] (1838)

F. Psychiatry and Psychology

Behavior and Behavior Mechanisms [MESH:D001520] (1594) Behavioral Disciplines and Activities [MESH:D004191] (173) Mental Disorders [MESH:D001523] (2063) Psychological Phenomena and Processes [MESH:D011579] (294)

G. Phenomena and Processes

Biological Phenomena [MESH:D001686] (141) Cell Physiological Phenomena [MESH:D002468] (161) Chemical Phenomena [MESH:D055598] (397) Circulatory and Respiratory Physiological Phenomena [MESH:D002943] (614) Digestive System and Oral Physiological Phenomena [MESH:D055688] (39) Genetic Phenomena [MESH:D055614] (1922) Immune System Phenomena [MESH:D055633] (113) Integumentary System Physiological Phenomena [MESH:D055827] (14) Metabolic Phenomena [MESH:D055754] (141) Microbiological Phenomena [MESH:D008827] (86) Musculoskeletal and Neural Physiological Phenomena [MESH:D055687] (260) Ocular Physiological Phenomena [MESH:D009799] (35) more...

I. Anthropology, Education, Sociology and Social Phenomena

Education [MESH:D004493] (98) Human Activities [MESH:D006802] (68) Social Sciences [MESH:D012942] (401)

J. Technology, Industry, Agriculture

Food and Beverages [MESH:D019602] (267) Technology, Industry, and Agriculture [MESH:D013676] (4406)

N. Health Care

Environment and Public Health [MESH:D004778] (505) Health Care Economics and Organizations [MESH:D004472] (372) Health Care Facilities, Manpower, and Services [MESH:D005159] (449) Health Care Quality, Access, and Evaluation [MESH:D017530] (292) Health Services Administration [MESH:D006298] (311) Population Characteristics [MESH:D011154] (103)