Item 28 of 566 (back to results) previous next   carbendazim C006698               MeSH Unique Identifier: C006698 Scope Notes: Carcinogen when combined with sodium nitrite; principle metabolite of thiophanate methyl & benomyl Chemical – Gene Interaction Note 1: Carbendazim results in increased activity of CYP19A1 protein Note 2: Carbendazim results in increased expression of CYP19A1 mRNA Click here for more information

Current search: 1. Human Genes: Cytochrome P450s [HGNC:CYP] > cytochrome P450, family 01, subfamily A, polypeptide 01 [HGNC:CYP1A1] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Cytochrome P450s [HGNC:CYP] (1673)   cytochrome P450, family 01, subfamily A, polypeptide 01 [HGNC:CYP1A1] (566)  cytochrome P450, family 01, subfamily A, polypeptide 02 [HGNC:CYP1A2] (466)  cytochrome P450, family 02, subfamily A, polypeptide 06 [HGNC:CYP2A6] (145)  cytochrome P450, family 02, subfamily B, polypeptide 06 [HGNC:CYP2B6] (216)  cytochrome P450, family 03, subfamily A, polypeptide 04 [HGNC:CYP3A4] (612)  cytochrome P450, family 19, subfamily A, polypeptide 01 [HGNC:CYP19A1] (210) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Increases (5571)   activity (2865)  expression (3238) A. Anatomy  A. Anatomy  Cells [MESH:D002477] (1885)   Cellular Structures [MESH:D022082] (1562)   Chromosomes [MESH:D002875] (1300)   Chromosomes, Mammalian [MESH:D033481] (1282)   Chromosomes, Human [MESH:D002877] (1280)   Chromosomes, Human, 21-22 and Y [MESH:D002904] (294)   Chromosomes, Human, Pair 22 [MESH:D002892] (250)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238) C02. Virus Diseases  C02. Virus Diseases  Virus Diseases [MESH:D014777] (4544)   DNA Virus Infections [MESH:D004266] (2474)   Hepadnaviridae Infections [MESH:D018347] (977)   Hepatitis B [MESH:D006509] (976)  Hepatitis, Viral, Human [MESH:D006525] (1766)   Hepatitis B [MESH:D006509] (976)  Hepatitis C [MESH:D006526] (1627)  RNA Virus Infections [MESH:D012327] (4215)   Flaviviridae Infections [MESH:D018178] (1656)   Hepatitis C [MESH:D006526] (1627) C03. Parasitic Diseases  C03. Parasitic Diseases  Parasitic Diseases [MESH:D010272] (3828)   Liver Diseases, Parasitic [MESH:D008109] (1009)  Helminthiasis [MESH:D006373] (1644)   Trematode Infections [MESH:D014201] (1182)   Opisthorchiasis [MESH:D009889] (160) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Hamartoma [MESH:D006222] (1484)  Cysts [MESH:D003560] (2625)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742)   Neoplasms, Connective Tissue [MESH:D009372] (3626)   Neoplasms, Bone Tissue [MESH:D018213] (2217)   Osteosarcoma [MESH:D012516] (2175)  Sarcoma [MESH:D012509] (4246)   Osteosarcoma [MESH:D012516] (2175)  Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126)   Neuroectodermal Tumors [MESH:D017599] (5066)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Gliosarcoma [MESH:D018316] (880)  Neuroendocrine Tumors [MESH:D018358] (3633)   Melanoma [MESH:D008545] (3508)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Carcinoma [MESH:D002277] (7263)   Carcinoma, Large Cell [MESH:D018287] (211)  Carcinoma, Small Cell [MESH:D018288] (1317)  Adenocarcinoma [MESH:D000230] (6565)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Carcinoma, Ductal [MESH:D044584] (1786)   Carcinoma, Ductal, Breast [MESH:D018270] (1112)  Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms, Ductal, Lobular, and Medullary [MESH:D018299] (1831)   Carcinoma, Ductal [MESH:D044584] (1786)   Carcinoma, Ductal, Breast [MESH:D018270] (1112)  Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Gliosarcoma [MESH:D018316] (880)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms, Nerve Tissue [MESH:D009380] (5201)   Neuroectodermal Tumors [MESH:D017599] (5059)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Gliosarcoma [MESH:D018316] (880)  Neuroendocrine Tumors [MESH:D018358] (3625)   Melanoma [MESH:D008545] (3508)  Nevi and Melanomas [MESH:D018326] (3572)   Melanoma [MESH:D008545] (3508)  Neoplasms by Site [MESH:D009371] (9169)   Breast Neoplasms [MESH:D001943] (6077)   Carcinoma, Ductal, Breast [MESH:D018270] (1112)  Digestive System Neoplasms [MESH:D004067] (7487)   Gastrointestinal Neoplasms [MESH:D005770] (6452)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5358)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Liver Neoplasms, Experimental [MESH:D008114] (2837)  Head and Neck Neoplasms [MESH:D006258] (4612)   Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Otorhinolaryngologic Neoplasms [MESH:D010039] (1557)   Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Mammary Neoplasms, Animal [MESH:D015674] (3404)   Mammary Neoplasms, Experimental [MESH:D008325] (3268)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Neoplasms, Experimental [MESH:D009374] (5218)   Liver Neoplasms, Experimental [MESH:D008114] (2837)  Mammary Neoplasms, Experimental [MESH:D008325] (3268) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Bone Diseases [MESH:D001847] (5801)   Bone Resorption [MESH:D001862] (2352)  Bone Diseases, Metabolic [MESH:D001851] (3492)   Osteoporosis [MESH:D010024] (3037)  Joint Diseases [MESH:D007592] (4657)   Arthritis [MESH:D001168] (4416)   Osteoarthritis [MESH:D010003] (1743)  Rheumatic Diseases [MESH:D012216] (4032)   Osteoarthritis [MESH:D010003] (1743) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Liver Neoplasms, Experimental [MESH:D008114] (2837)  Gastrointestinal Diseases [MESH:D005767] (7443)   Esophageal Diseases [MESH:D004935] (4255)   Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Intestinal Diseases [MESH:D007410] (6206)   Colonic Diseases [MESH:D003108] (5564)   Colorectal Neoplasms [MESH:D015179] (5282)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Rectal Diseases [MESH:D012002] (4596)   Colorectal Neoplasms [MESH:D015179] (4534)  Stomach Diseases [MESH:D013272] (5325)   Stomach Neoplasms [MESH:D013274] (4942)  Liver Diseases [MESH:D008107] (8167)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Fatty Liver [MESH:D005234] (3584)  Hepatomegaly [MESH:D006529] (1169)  Liver Diseases, Parasitic [MESH:D008109] (1009)  Hepatitis [MESH:D006505] (3883)   Hepatitis, Viral, Human [MESH:D006525] (1766)   Hepatitis B [MESH:D006509] (976)  Hepatitis C [MESH:D006526] (1627)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Experimental [MESH:D008106] (4589)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Liver Neoplasms, Experimental [MESH:D008114] (2837)  Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Pharyngeal Diseases [MESH:D010608] (1562)   Nasopharyngeal Diseases [MESH:D009302] (1508)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Lung Neoplasms [MESH:D008175] (6012)  Lung Diseases, Obstructive [MESH:D008173] (4697)   Pulmonary Disease, Chronic Obstructive [MESH:D029424] (3564)   Pulmonary Emphysema [MESH:D011656] (1259)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013) C09. Otorhinolaryngologic Diseases  C09. Otorhinolaryngologic Diseases  Otorhinolaryngologic Diseases [MESH:D010038] (3827)   Otorhinolaryngologic Neoplasms [MESH:D010039] (1561)   Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Diseases [MESH:D010608] (1605)   Nasopharyngeal Diseases [MESH:D009302] (1508)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Cerebellar Diseases [MESH:D002526] (736)   Spinocerebellar Degenerations [MESH:D013132] (449)  Dementia [MESH:D003704] (4498)   Alzheimer Disease [MESH:D000544] (4275)  Epilepsy [MESH:D004827] (6274)   Seizures [MESH:D012640] (4502)  Hypothalamic Diseases [MESH:D007027] (1833)   Pituitary Diseases [MESH:D010900] (1808)   Hypopituitarism [MESH:D007018] (732)  Spinal Cord Diseases [MESH:D013118] (4376)   Spinocerebellar Degenerations [MESH:D013132] (449)  Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Nervous System Malformations [MESH:D009421] (3354)   Neural Tube Defects [MESH:D009436] (2143)  Neurodegenerative Diseases [MESH:D019636] (6613)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3243)   Spinocerebellar Degenerations [MESH:D013132] (449)  Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Tauopathies [MESH:D024801] (4289)   Alzheimer Disease [MESH:D000544] (4275)  TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Neurologic Manifestations [MESH:D009461] (8964)   Seizures [MESH:D012640] (4514)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Intellectual Disability [MESH:D008607] (3054)  Communication Disorders [MESH:D003147] (2918)   Language Disorders [MESH:D007806] (653)   Language Development Disorders [MESH:D007805] (351)  Neuromuscular Diseases [MESH:D009468] (7336)   Peripheral Nervous System Diseases [MESH:D010523] (6151)  Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Uveal Diseases [MESH:D014603] (2428)   Iris Diseases [MESH:D007499] (348)   Exfoliation Syndrome [MESH:D017889] (48) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Infertility [MESH:D007246] (2909)   Infertility, Male [MESH:D007248] (2851)   Aromatase deficiency [MESH:C537436] (277)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Abnormalities [MESH:D014564] (2065)   Disorders of Sex Development [MESH:D012734] (1637)   46, XX Disorders of Sex Development [MESH:D058489] (644)   Aromatase deficiency [MESH:C537436] (277)  Gonadal Dysgenesis [MESH:D006059] (492)   Sexual Infantilism [MESH:D050035] (277)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4374)   Urinary Bladder Neoplasms [MESH:D001749] (4079) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Endometriosis [MESH:D004715] (2461)  Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Infertility [MESH:D007246] (2211)   Infertility, Female [MESH:D007247] (2184)  Urogenital Abnormalities [MESH:D014564] (2043)   Disorders of Sex Development [MESH:D012734] (1637)   46, XX Disorders of Sex Development [MESH:D058489] (644)   Aromatase deficiency [MESH:C537436] (277)  Gonadal Dysgenesis [MESH:D006059] (492)   Sexual Infantilism [MESH:D050035] (277)  Urogenital Neoplasms [MESH:D014565] (5792)   Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4375)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Pregnancy Complications [MESH:D011248] (4768)   Abortion, Spontaneous [MESH:D000022] (2780)  Diabetes, Gestational [MESH:D016640] (1157)  Prenatal Injuries [MESH:D049188] (1314) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Cardiomegaly [MESH:D006332] (4081)  Arrhythmias, Cardiac [MESH:D001145] (4679)   Tachycardia [MESH:D013610] (3339)   Tachycardia, Ventricular [MESH:D017180] (1386)   Torsades de Pointes [MESH:D016171] (880)  Vascular Diseases [MESH:D014652] (8691)   Arteritis [MESH:D001167] (1084)  Hypertension [MESH:D006973] (5655)  Peripheral Vascular Diseases [MESH:D016491] (1412)  Vasculitis [MESH:D014657] (2604)   Arteritis [MESH:D001167] (1084) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Methemoglobinemia [MESH:D008708] (850)  Lymphatic Diseases [MESH:D008206] (5167)   Splenic Diseases [MESH:D013158] (1323) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Chromosome Disorders [MESH:D025063] (2030)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Nervous System Malformations [MESH:D009421] (3354)   Neural Tube Defects [MESH:D009436] (2143)  Urogenital Abnormalities [MESH:D014564] (2064)   Disorders of Sex Development [MESH:D012734] (1637)   46, XX Disorders of Sex Development [MESH:D058489] (644)   Aromatase deficiency [MESH:C537436] (277)  Gonadal Dysgenesis [MESH:D006059] (492)   Sexual Infantilism [MESH:D050035] (277)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Chromosome Disorders [MESH:D025063] (2030)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Heredodegenerative Disorders, Nervous System [MESH:D020271] (3465)   Spinocerebellar Degenerations [MESH:D013132] (449)  Metabolism, Inborn Errors [MESH:D008661] (6032)   Aromatase deficiency [MESH:C537436] (277)  Coumarin Resistance [MESH:C563039] (397)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Skin Diseases, Genetic [MESH:D012873] (3456)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Connective Tissue Diseases [MESH:D003240] (4490)   Lupus Erythematosus, Systemic [MESH:D008180] (2317)  Skin Diseases [MESH:D012871] (8774)   Breast Diseases [MESH:D001941] (6148)   Breast Neoplasms [MESH:D001943] (6077)   Carcinoma, Ductal, Breast [MESH:D018270] (1112)  Gynecomastia [MESH:D006177] (484)   Aromatase deficiency [MESH:C537436] (277)  Dermatitis [MESH:D003872] (4530)   Drug Eruptions [MESH:D003875] (2697)  Dermatitis, Contact [MESH:D003877] (3394)   Dermatitis, Allergic Contact [MESH:D017449] (3241)  Skin Diseases, Eczematous [MESH:D017443] (3740)   Dermatitis, Contact [MESH:D003877] (3394)   Dermatitis, Allergic Contact [MESH:D017449] (3241)  Skin Diseases, Genetic [MESH:D012873] (3481)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Glucose Metabolism Disorders [MESH:D044882] (6122)   Diabetes Mellitus [MESH:D003920] (5891)   Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Diabetes, Gestational [MESH:D016640] (1152)  Metabolism, Inborn Errors [MESH:D008661] (6028)   Aromatase deficiency [MESH:C537436] (277)  Coumarin Resistance [MESH:C563039] (397)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Proteostasis Deficiencies [MESH:D057165] (3522)   TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Diabetes Mellitus [MESH:D003920] (6159)   Diabetes, Gestational [MESH:D016640] (1152)  Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Gonadal Disorders [MESH:D006058] (5088)   Disorders of Sex Development [MESH:D012734] (1637)   46, XX Disorders of Sex Development [MESH:D058489] (644)   Aromatase deficiency [MESH:C537436] (277)  Gonadal Dysgenesis [MESH:D006059] (492)   Sexual Infantilism [MESH:D050035] (277)  Hypogonadism [MESH:D007006] (1123)   Sexual Infantilism [MESH:D050035] (277)  Ovarian Diseases [MESH:D010049] (4253)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Pituitary Diseases [MESH:D010900] (1829)   Hypopituitarism [MESH:D007018] (732) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Autoimmune Diseases [MESH:D001327] (5067)   Lupus Erythematosus, Systemic [MESH:D008180] (2317)  Hypersensitivity [MESH:D006967] (5873)   Drug Hypersensitivity [MESH:D004342] (4000)   Drug Eruptions [MESH:D003875] (2695)  Hypersensitivity, Delayed [MESH:D006968] (3408)   Dermatitis, Allergic Contact [MESH:D017449] (3241) C22. Animal Diseases  C22. Animal Diseases  Animal Diseases [MESH:D000820] (3656)   Mammary Neoplasms, Animal [MESH:D015674] (2735) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Atrophy [MESH:D001284] (2603)  Hypertrophy [MESH:D006984] (4476)   Cardiomegaly [MESH:D006332] (3802)  Hepatomegaly [MESH:D006529] (1169)  Splenomegaly [MESH:D013163] (1258)  Pathologic Processes [MESH:D010335] (9863)   Fibrosis [MESH:D005355] (3133)  Growth Disorders [MESH:D006130] (2438)  Necrosis [MESH:D009336] (4019)  Arrhythmias, Cardiac [MESH:D001145] (4658)   Tachycardia [MESH:D013610] (3339)   Tachycardia, Ventricular [MESH:D017180] (1386)   Torsades de Pointes [MESH:D016171] (880)  Chromosome Aberrations [MESH:D002869] (2352)   Aneuploidy [MESH:D000782] (1237)   Monosomy [MESH:D009006] (1121)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Disease Attributes [MESH:D020969] (3654)   Critical Illness [MESH:D016638] (296)  Disease Progression [MESH:D018450] (2868)  Menstruation Disturbances [MESH:D008599] (926)   Amenorrhea [MESH:D000568] (817)  Metaplasia [MESH:D008679] (1469)   Neovascularization, Pathologic [MESH:D009389] (829)  Signs and Symptoms [MESH:D012816] (10659)   Neurologic Manifestations [MESH:D009461] (8702)   Seizures [MESH:D012640] (4502)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Intellectual Disability [MESH:D008607] (1476)  Communication Disorders [MESH:D003147] (2918)   Language Disorders [MESH:D007806] (653)   Language Development Disorders [MESH:D007805] (351) C24. Occupational Diseases  C24. Occupational Diseases  Occupational Diseases [MESH:D009784] (3402)  Z. Exceptions (1530)   Not Fully Specified [NFS] (1530) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Drug Hypersensitivity [MESH:D004342] (4001)   Drug Eruptions [MESH:D003875] (2697)  Poisoning [MESH:D011041] (6703)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Substance-Related Disorders [MESH:D019966] (6308)   Tobacco Use Disorder [MESH:D014029] (628) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Carboxylic Acids [MESH:D002264] (13103)   Acids, Acyclic [MESH:D000144] (7142)   Carbamates [MESH:D002219] (821) D03. Heterocyclic Compounds  D03. Heterocyclic Compounds  Heterocyclic Compounds [MESH:D006571] (56330)   Heterocyclic Compounds, 2-Ring [MESH:D006574] (24204)   Benzimidazoles [MESH:D001562] (702) D27. Chemical Actions and Uses  D27. Chemical Actions and Uses  Pharmacologic Actions [MESH:D020228] (2566)   Therapeutic Uses [MESH:D045506] (1611)   Anti-Infective Agents [MESH:D000890] (386)   Antiparasitic Agents [MESH:D000977] (87)   Anthelmintics [MESH:D000871] (27)   Antinematodal Agents [MESH:D000969] (10)  Specialty Uses of Chemicals [MESH:D020313] (713)   Agrochemicals [MESH:D016573] (69)   Pesticides [MESH:D010575] (67)   Fungicides, Industrial [MESH:D005659] (12)  Pesticides [MESH:D010575] (68)   Fungicides, Industrial [MESH:D005659] (12)  Toxic Actions [MESH:D004786] (206)   Noxae [MESH:D009676] (136)   Mutagens [MESH:D009153] (33)  Pesticides [MESH:D010575] (67)   Fungicides, Industrial [MESH:D005659] (12) F. Psychiatry and Psychology  F. Psychiatry and Psychology  Mental Disorders [MESH:D001523] (2063)   Sexual and Gender Disorders [MESH:D019968] (624)   Disorders of Sex Development [MESH:D012734] (609)   46, XX Disorders of Sex Development [MESH:D058489] (375)   Aromatase deficiency [MESH:C537436] (277) G. Phenomena and Processes  G. Phenomena and Processes  Genetic Phenomena [MESH:D055614] (1922)   Genetic Processes [MESH:D039361] (1336)   Mutagenesis [MESH:D016296] (1150)   Sequence Deletion [MESH:D017384] (1120)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Genetic Structures [MESH:D040342] (1612)   Chromosomes [MESH:D002875] (1304)   Chromosomes, Mammalian [MESH:D033481] (1282)   Chromosomes, Human [MESH:D002877] (1280)   Chromosomes, Human, 21-22 and Y [MESH:D002904] (294)   Chromosomes, Human, Pair 22 [MESH:D002892] (250)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Genetic Variation [MESH:D014644] (1337)   Mutation [MESH:D009154] (1327)   Allelic Imbalance [MESH:D022981] (1120)   Loss of Heterozygosity [MESH:D019656] (1119)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Chromosome Aberrations [MESH:D002869] (1297)   Aneuploidy [MESH:D000782] (1220)   Monosomy [MESH:D009006] (1121)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Sequence Deletion [MESH:D017384] (1120)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)  Ploidies [MESH:D011003] (1227)   Aneuploidy [MESH:D000782] (1220)   Monosomy [MESH:D009006] (1121)   Chromosome Deletion [MESH:D002872] (1117)   Telomeric 22q13 Monosomy Syndrome [MESH:C536801] (238)