Item 8 of 10 (back to results) previous next   Mazindol D008454               MeSH Unique Identifier: D008454 Scope Notes: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. Chemical – Gene Interaction Note 1: Mazindol inhibits the reaction [[GDNF protein co-treated with Cyclic AMP] results in increased susceptibility to 1-Methyl-4-phenylpyridinium] Note 2: Mazindol binds to SLC18A2 protein Click here for more information

Current search: C12. Male Urogenital Diseases: Z. Exceptions > Not Fully Specified [NFS] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Solute carriers [HGNC:SLC] (716)   solute carrier family 06 (neurotransmitter transporter), member 03 [HGNC:SLC6A3] (47)  solute carrier family 06 (neurotransmitter transporter), member 04 [HGNC:SLC6A4] (41)  solute carrier family 18 (vesicular monoamine transporter), member 2 [HGNC:SLC18A2] (16) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   binding (2423)  cotreatment (1499)  Decreases (5154)   activity (2549)  reaction (3393)  response to substance (713)  Increases (5571)   response to substance (641)  uptake (378) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126)   Neuroectodermal Tumors [MESH:D017599] (5066)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Ependymoma [MESH:D004806] (76)  Oligodendroglioma [MESH:D009837] (241)  Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neuroendocrine Tumors [MESH:D018358] (3633)   Paraganglioma [MESH:D010235] (297)   Pheochromocytoma [MESH:D010673] (275)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Ependymoma [MESH:D004806] (76)  Oligodendroglioma [MESH:D009837] (241)  Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neoplasms, Nerve Tissue [MESH:D009380] (5201)   Neuroectodermal Tumors [MESH:D017599] (5059)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Ependymoma [MESH:D004806] (76)  Oligodendroglioma [MESH:D009837] (241)  Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neuroendocrine Tumors [MESH:D018358] (3625)   Paraganglioma [MESH:D010235] (297)   Pheochromocytoma [MESH:D010673] (275) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Abnormalities [MESH:D004065] (2127)   Hirschsprung Disease [MESH:D006627] (361)  Gastrointestinal Diseases [MESH:D005767] (7443)   Intestinal Diseases [MESH:D007410] (6206)   Intestinal Perforation [MESH:D007416] (471)  Colonic Diseases [MESH:D003108] (5564)   Megacolon [MESH:D008531] (386)   Hirschsprung Disease [MESH:D006627] (361) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Mouth Diseases [MESH:D009059] (4783)   Salivary Gland Diseases [MESH:D012466] (1213)   Xerostomia [MESH:D014987] (98) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Hypertension, Pulmonary [MESH:D006976] (2000)  Respiration Disorders [MESH:D012120] (2218)   Apnea [MESH:D001049] (748)   Sleep Apnea Syndromes [MESH:D012891] (570)   Sleep Apnea, Central [MESH:D020182] (347)   Congenital central hypoventilation syndrome [MESH:C536209] (341)  Respiratory Insufficiency [MESH:D012131] (841)   Hypoventilation [MESH:D007040] (360)   Congenital central hypoventilation syndrome [MESH:C536209] (341) C10. Nervous System Diseases  C10. Nervous System Diseases  Z. Exceptions (4027)   Not Fully Specified [NFS] (4027)  Nervous System Diseases [MESH:D009422] (13325)   Trauma, Nervous System [MESH:D020196] (3997)  Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Basal Ganglia Diseases [MESH:D001480] (4268)   Huntington Disease [MESH:D006816] (540)  Parkinsonian Disorders [MESH:D020734] (4009)   Parkinson Disease, Secondary [MESH:D010302] (327)  Parkinson Disease [MESH:D010300] (3595)   Parkinsonism-Dystonia, Infantile [MESH:C567730] (119)  Dementia [MESH:D003704] (4498)   Huntington Disease [MESH:D006816] (540)  Epilepsy [MESH:D004827] (6274)   Seizures [MESH:D012640] (4502)  Status Epilepticus [MESH:D013226] (4014)  Movement Disorders [MESH:D009069] (4823)   Tic Disorders [MESH:D013981] (256)  Dyskinesias [MESH:D020820] (1827)   Dyskinesia, Drug-Induced [MESH:D004409] (1389)  Chorea [MESH:D002819] (651)   Huntington Disease [MESH:D006816] (540)  Dystonic Disorders [MESH:D020821] (729)   Parkinsonism-Dystonia, Infantile [MESH:C567730] (119)  Parkinsonian Disorders [MESH:D020734] (4009)   Parkinson Disease, Secondary [MESH:D010302] (327)  Parkinson Disease [MESH:D010300] (3595)   Parkinsonism-Dystonia, Infantile [MESH:C567730] (119)  Neurodegenerative Diseases [MESH:D019636] (6613)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3243)   Huntington Disease [MESH:D006816] (540)  Parkinson Disease [MESH:D010300] (3595)   Parkinsonism-Dystonia, Infantile [MESH:C567730] (119)  Neurologic Manifestations [MESH:D009461] (8964)   Pain [MESH:D010146] (3875)  Seizures [MESH:D012640] (4514)  Dyskinesias [MESH:D020820] (3365)   Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Memory Disorders [MESH:D008569] (3233)  Sensation Disorders [MESH:D012678] (5011)   Dizziness [MESH:D004244] (289)  Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Neurotoxicity Syndromes [MESH:D020258] (4570)   Dyskinesia, Drug-Induced [MESH:D004409] (1389)  Sleep Disorders [MESH:D012893] (2050)   Dyssomnias [MESH:D020920] (1417)   Sleep Disorders, Intrinsic [MESH:D020919] (1270)   Sleep Initiation and Maintenance Disorders [MESH:D007319] (354)  Disorders of Excessive Somnolence [MESH:D006970] (581)   Narcolepsy [MESH:D009290] (478)   Cataplexy [MESH:D002385] (20)  Sleep Apnea Syndromes [MESH:D012891] (570)   Sleep Apnea, Central [MESH:D020182] (347)   Congenital central hypoventilation syndrome [MESH:C536209] (341) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Retinal Diseases [MESH:D012164] (3747)   Retinal Degeneration [MESH:D012162] (2386) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Z. Exceptions (10)   Not Fully Specified [NFS] (10)  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Testicular Diseases [MESH:D013733] (451)  Sexual Dysfunction, Physiological [MESH:D012735] (1808)   Erectile Dysfunction [MESH:D007172] (1791)  Urologic Diseases [MESH:D014570] (7792)   Urination Disorders [MESH:D014555] (3598)   Urinary Retention [MESH:D016055] (411) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Urologic Diseases [MESH:D014570] (7793)   Urination Disorders [MESH:D014555] (3598)   Urinary Retention [MESH:D016055] (411) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Cardiomyopathies [MESH:D009202] (5331)  Heart Valve Diseases [MESH:D006349] (3333)   Aortic Valve Insufficiency [MESH:D001022] (1002)  Mitral Valve Insufficiency [MESH:D008944] (35)  Vascular Diseases [MESH:D014652] (8691)   Hypertension [MESH:D006973] (5655) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Digestive System Abnormalities [MESH:D004065] (507)   Hirschsprung Disease [MESH:D006627] (361)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3465)   Huntington Disease [MESH:D006816] (540) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Glucose Metabolism Disorders [MESH:D044882] (6122)   Diabetes Mellitus [MESH:D003920] (5891)   Diabetes Mellitus, Type 1 [MESH:D003922] (1897)  Hyperinsulinism [MESH:D006946] (3586)   Insulin Resistance [MESH:D007333] (3511)  Nutrition Disorders [MESH:D009748] (4945)   Overnutrition [MESH:D044343] (4463)   Obesity [MESH:D009765] (4462) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Diabetes Mellitus [MESH:D003920] (6159)   Diabetes Mellitus, Type 1 [MESH:D003922] (1897)  Gonadal Disorders [MESH:D006058] (5088)   Testicular Diseases [MESH:D013733] (777) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Autoimmune Diseases [MESH:D001327] (5067)   Diabetes Mellitus, Type 1 [MESH:D003922] (1893) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Ventricular Remodeling [MESH:D020257] (686)  Pathologic Processes [MESH:D010335] (9863)   Nerve Degeneration [MESH:D009410] (4061)  Chromosome Aberrations [MESH:D002869] (2352)   Micronuclei, Chromosome-Defective [MESH:D048629] (1013)  Death [MESH:D003643] (1328)   Death, Sudden [MESH:D003645] (725)   Sudden Infant Death [MESH:D013398] (268)  Signs and Symptoms [MESH:D012816] (10659)   Pain [MESH:D010146] (4511)  Body Temperature Changes [MESH:D001832] (3130)   Fever [MESH:D005334] (2856)  Hypothermia [MESH:D007035] (2075)  Body Weight [MESH:D001835] (4972)   Overweight [MESH:D050177] (4455)   Obesity [MESH:D009765] (4454)  Neurologic Manifestations [MESH:D009461] (8702)   Pain [MESH:D010146] (3869)  Seizures [MESH:D012640] (4502)  Dyskinesias [MESH:D020820] (3285)   Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Memory Disorders [MESH:D008569] (3233)  Sensation Disorders [MESH:D012678] (5009)   Dizziness [MESH:D004244] (289)  Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Signs and Symptoms, Digestive [MESH:D012817] (3095)   Nausea [MESH:D009325] (2300)  Signs and Symptoms, Respiratory [MESH:D012818] (2724)   Anoxia [MESH:D000860] (1698)  Hypoventilation [MESH:D007040] (359)   Congenital central hypoventilation syndrome [MESH:C536209] (341)  Urological Manifestations [MESH:D020924] (3532)   Lower Urinary Tract Symptoms [MESH:D059411] (612)   Dysuria [MESH:D053159] (29) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Dyskinesia, Drug-Induced [MESH:D004409] (1389)  Poisoning [MESH:D011041] (6703)   Psychoses, Substance-Induced [MESH:D011605] (2053)  Neurotoxicity Syndromes [MESH:D020258] (3323)   Dyskinesia, Drug-Induced [MESH:D004409] (1389)  Substance-Related Disorders [MESH:D019966] (6308)   Amphetamine-Related Disorders [MESH:D019969] (2858)  Cocaine-Related Disorders [MESH:D019970] (3054)  Psychoses, Substance-Induced [MESH:D011605] (2052)  Substance Withdrawal Syndrome [MESH:D013375] (2956)  Alcohol-Related Disorders [MESH:D019973] (3869)   Alcoholism [MESH:D000437] (1519)  Opioid-Related Disorders [MESH:D009293] (1491)   Morphine Dependence [MESH:D009021] (855) C26. Wounds and Injuries  C26. Wounds and Injuries  Wounds and Injuries [MESH:D014947] (5171)   Trauma, Nervous System [MESH:D020196] (3535)  Radiation Injuries [MESH:D011832] (2718)   Radiation Injuries, Experimental [MESH:D011833] (2662) D03. Heterocyclic Compounds  D03. Heterocyclic Compounds  Heterocyclic Compounds [MESH:D006571] (56330)   Heterocyclic Compounds, 2-Ring [MESH:D006574] (24204)   Isoindoles [MESH:D054833] (315)   Mazindol [MESH:D008454] (4) F. Psychiatry and Psychology  F. Psychiatry and Psychology  Mental Disorders [MESH:D001523] (2063)   Mood Disorders [MESH:D019964] (257)   Affective Disorders, Psychotic [MESH:D000341] (248)   Bipolar Disorder [MESH:D001714] (247)   Major Affective Disorder 1 [MESH:C565111] (237)