Item 4 of 4 (back to results) previous   Aminocaproic Acid D015119               MeSH Unique Identifier: D015119 Scope Notes: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties. Chemical – Gene Interaction Note 1: Aminocaproic Acid results in decreased expression of A2M protein Note 2: Aminocaproic Acid results in increased expression of SERPINC1 protein Click here for more information

Current search: C14. Cardiovascular Diseases: Cardiovascular Diseases [MESH:D002318] > Vascular Diseases [MESH:D014652] > Vasculitis [MESH:D014657] > Shwartzman Phenomenon [MESH:D012790] × Select any link to see items in a related category. more general categories    information about this item 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Decreases (5154)   expression (2187)  Increases (5571)   expression (3238) C01. Bacterial Infections and Mycoses  C01. Bacterial Infections and Mycoses  Infection [MESH:D007239] (4109)   Sepsis [MESH:D018805] (3556) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Adenoma [MESH:D000236] (4051)   Adenoma, Liver Cell [MESH:D018248] (685)  Carcinoma [MESH:D002277] (7263)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Adenocarcinoma [MESH:D000230] (6565)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Neoplasms by Site [MESH:D009371] (9169)   Head and Neck Neoplasms [MESH:D006258] (4612)  Digestive System Neoplasms [MESH:D004067] (7487)   Gastrointestinal Neoplasms [MESH:D005770] (6452)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5358)   Colorectal Neoplasms [MESH:D015179] (5294)   Colonic Neoplasms [MESH:D003110] (4405)  Liver Neoplasms [MESH:D008113] (6048)   Adenoma, Liver Cell [MESH:D018248] (685)  Carcinoma, Hepatocellular [MESH:D006528] (5375)  Endocrine Gland Neoplasms [MESH:D004701] (4925)   Ovarian Neoplasms [MESH:D010051] (3275)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)  Urogenital Neoplasms [MESH:D014565] (7002)   Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Muscular Diseases [MESH:D009135] (4071)   Rhabdomyolysis [MESH:D012206] (465)   Myoglobinuria [MESH:D009212] (96) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Colonic Neoplasms [MESH:D003110] (4405)  Liver Neoplasms [MESH:D008113] (6048)   Adenoma, Liver Cell [MESH:D018248] (685)  Carcinoma, Hepatocellular [MESH:D006528] (5375)  Gastrointestinal Diseases [MESH:D005767] (7443)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Colonic Neoplasms [MESH:D003110] (4405)  Intestinal Diseases [MESH:D007410] (6206)   Colonic Diseases [MESH:D003108] (5564)   Colorectal Neoplasms [MESH:D015179] (5282)   Colonic Neoplasms [MESH:D003110] (4405)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Colonic Neoplasms [MESH:D003110] (4405)  Stomach Diseases [MESH:D013272] (5325)   Stomach Neoplasms [MESH:D013274] (4942)  Liver Diseases [MESH:D008107] (8167)   Hepatic Insufficiency [MESH:D048550] (2771)   Liver Failure [MESH:D017093] (2768)   Liver Failure, Acute [MESH:D017114] (2404)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Experimental [MESH:D008106] (4589)  Liver Neoplasms [MESH:D008113] (6048)   Adenoma, Liver Cell [MESH:D018248] (685)  Carcinoma, Hepatocellular [MESH:D006528] (5375) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Lung Neoplasms [MESH:D008175] (6012)  Respiratory Distress Syndrome, Adult [MESH:D012128] (864)  Respiration Disorders [MESH:D012120] (2218)   Respiratory Distress Syndrome, Adult [MESH:D012128] (864)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Brain Injuries [MESH:D001930] (3429)  Hydrocephalus [MESH:D006849] (276)  Cerebrovascular Disorders [MESH:D002561] (5542)   Brain Ischemia [MESH:D002545] (4873)  Vasospasm, Intracranial [MESH:D020301] (324)  Intracranial Embolism and Thrombosis [MESH:D002542] (490)   Intracranial Thrombosis [MESH:D020767] (481)   Sinus Thrombosis, Intracranial [MESH:D012851] (356)   Sagittal Sinus Thrombosis [MESH:D020225] (223)  Intracranial Hemorrhages [MESH:D020300] (3269)   Cerebral Hemorrhage [MESH:D002543] (2873)  Subarachnoid Hemorrhage [MESH:D013345] (1082)  Dementia [MESH:D003704] (4498)   Alzheimer Disease [MESH:D000544] (4275)  Intracranial Hypertension [MESH:D019586] (368)   Hydrocephalus [MESH:D006849] (274)  Neurodegenerative Diseases [MESH:D019636] (6613)   Tauopathies [MESH:D024801] (4289)   Alzheimer Disease [MESH:D000544] (4275)  Neurologic Manifestations [MESH:D009461] (8964)   Pain [MESH:D010146] (3875)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Confusion [MESH:D003221] (284)   Delirium [MESH:D003693] (173)  Consciousness Disorders [MESH:D003244] (680)   Unconsciousness [MESH:D014474] (660)   Syncope [MESH:D013575] (128)  Perceptual Disorders [MESH:D010468] (343)   Hallucinations [MESH:D006212] (251)  Sensation Disorders [MESH:D012678] (5011)   Dizziness [MESH:D004244] (289)  Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Neuromuscular Diseases [MESH:D009468] (7336)   Muscular Diseases [MESH:D009135] (3538)  Trauma, Nervous System [MESH:D020196] (3997)   Craniocerebral Trauma [MESH:D006259] (3507)   Brain Injuries [MESH:D001930] (3431) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Eye Injuries [MESH:D005131] (8)  Conjunctival Diseases [MESH:D003229] (273)   Conjunctivitis [MESH:D003231] (133)   Plasminogen Deficiency, Type I [MESH:C566897] (83)  Eye Hemorrhage [MESH:D005130] (94)   Hyphema [MESH:D006988] (3) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Urogenital Neoplasms [MESH:D014565] (6932)   Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)  Nephrosis [MESH:D009401] (2228)   Nephrotic Syndrome [MESH:D009404] (1536)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urinary Bladder Diseases [MESH:D001745] (4374)   Cystitis [MESH:D003556] (604)  Urination Disorders [MESH:D014555] (3598)   Hematuria [MESH:D006417] (477) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Ovarian Neoplasms [MESH:D010051] (3281)  Infertility [MESH:D007246] (2211)   Infertility, Female [MESH:D007247] (2184)  Uterine Diseases [MESH:D014591] (2479)   Uterine Hemorrhage [MESH:D014592] (38)   Menorrhagia [MESH:D008595] (14)  Urogenital Neoplasms [MESH:D014565] (5792)   Genital Neoplasms, Female [MESH:D005833] (3810)   Ovarian Neoplasms [MESH:D010051] (3281)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)  Nephrosis [MESH:D009401] (2228)   Nephrotic Syndrome [MESH:D009404] (1536)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urinary Bladder Diseases [MESH:D001745] (4375)   Cystitis [MESH:D003556] (604)  Urination Disorders [MESH:D014555] (3598)   Hematuria [MESH:D006417] (477) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Cardiomyopathies [MESH:D009202] (5331)  Myocardial Ischemia [MESH:D017202] (5787)   Acute Coronary Syndrome [MESH:D054058] (2286)  Angina Pectoris [MESH:D000787] (2575)   Acute Coronary Syndrome [MESH:D054058] (2286)  Vascular Diseases [MESH:D014652] (8691)   Angioedema [MESH:D000799] (837)  Aortic Diseases [MESH:D001018] (1737)  Hypertension [MESH:D006973] (5655)  Hypotension [MESH:D007022] (4045)  Cerebrovascular Disorders [MESH:D002561] (5541)   Brain Ischemia [MESH:D002545] (4873)  Vasospasm, Intracranial [MESH:D020301] (324)  Intracranial Embolism and Thrombosis [MESH:D002542] (550)   Intracranial Thrombosis [MESH:D020767] (481)   Sinus Thrombosis, Intracranial [MESH:D012851] (356)   Sagittal Sinus Thrombosis [MESH:D020225] (223)  Intracranial Hemorrhages [MESH:D020300] (3269)   Cerebral Hemorrhage [MESH:D002543] (2873)  Subarachnoid Hemorrhage [MESH:D013345] (1082)  Embolism and Thrombosis [MESH:D016769] (3374)   Thromboembolism [MESH:D013923] (732)   Venous Thromboembolism [MESH:D054556] (400)  Intracranial Embolism and Thrombosis [MESH:D002542] (550)   Intracranial Thrombosis [MESH:D020767] (481)   Sinus Thrombosis, Intracranial [MESH:D012851] (356)   Sagittal Sinus Thrombosis [MESH:D020225] (223)  Thrombosis [MESH:D013927] (3101)   Venous Thrombosis [MESH:D020246] (1141)  Thromboembolism [MESH:D013923] (732)   Venous Thromboembolism [MESH:D054556] (400)  Intracranial Embolism and Thrombosis [MESH:D002542] (550)   Intracranial Thrombosis [MESH:D020767] (481)   Sinus Thrombosis, Intracranial [MESH:D012851] (356)   Sagittal Sinus Thrombosis [MESH:D020225] (223)  Hemostatic Disorders [MESH:D020141] (2894)   Shwartzman Phenomenon [MESH:D012790] (4)  Myocardial Ischemia [MESH:D017202] (5791)   Acute Coronary Syndrome [MESH:D054058] (2286)  Angina Pectoris [MESH:D000787] (2575)   Acute Coronary Syndrome [MESH:D054058] (2286)  Vasculitis [MESH:D014657] (2604)   Shwartzman Phenomenon [MESH:D012790] (4) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Blood Coagulation Disorders [MESH:D001778] (1828)   Disseminated Intravascular Coagulation [MESH:D004211] (462)  Blood Coagulation Disorders, Inherited [MESH:D025861] (720)   Antithrombin III Deficiency [MESH:D020152] (80)  Blood Platelet Disorders [MESH:D001791] (3174)   Thrombocytopenia [MESH:D013921] (2966)   Thrombotic Microangiopathies [MESH:D057049] (2598)  Blood Protein Disorders [MESH:D001796] (3051)   Antithrombin III Deficiency [MESH:D020152] (80)  Hemorrhagic Disorders [MESH:D006474] (3359)   Disseminated Intravascular Coagulation [MESH:D004211] (462)  Hemostatic Disorders [MESH:D020141] (2932)   Shwartzman Phenomenon [MESH:D012790] (4)  Thrombophilia [MESH:D019851] (592)   Antithrombin III Deficiency [MESH:D020152] (80)  Disseminated Intravascular Coagulation [MESH:D004211] (462) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Genetic Diseases, Inborn [MESH:D030342] (9766)   Blood Coagulation Disorders, Inherited [MESH:D025861] (722)   Antithrombin III Deficiency [MESH:D020152] (80)  Skin Diseases, Genetic [MESH:D012873] (3456)   Plasminogen Deficiency, Type I [MESH:C566897] (83) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Skin Diseases [MESH:D012871] (8774)   Skin Diseases, Genetic [MESH:D012873] (3481)   Plasminogen Deficiency, Type I [MESH:C566897] (83)  Skin Diseases, Vascular [MESH:D017445] (3288)   Urticaria [MESH:D014581] (2668)   Angioedema [MESH:D000799] (837) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Glucose Metabolism Disorders [MESH:D044882] (6122)   Hyperglycemia [MESH:D006943] (1858) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Endocrine Gland Neoplasms [MESH:D004701] (4925)   Ovarian Neoplasms [MESH:D010051] (3275)  Gonadal Disorders [MESH:D006058] (5088)   Ovarian Diseases [MESH:D010049] (4253)   Ovarian Neoplasms [MESH:D010051] (3281) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Hypersensitivity [MESH:D006967] (5873)   Drug Hypersensitivity [MESH:D004342] (4000)  Hypersensitivity, Immediate [MESH:D006969] (4980)   Urticaria [MESH:D014581] (2668)   Angioedema [MESH:D000799] (837) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Atrophy [MESH:D001284] (2603)  Hypertrophy [MESH:D006984] (4476)  Pathologic Processes [MESH:D010335] (9863)   Gliosis [MESH:D005911] (1419)  Hyperbilirubinemia [MESH:D006932] (1860)  Necrosis [MESH:D009336] (4019)  Nerve Degeneration [MESH:D009410] (4061)  Hemorrhage [MESH:D006470] (4451)   Hematuria [MESH:D006417] (477)  Eye Hemorrhage [MESH:D005130] (94)   Hyphema [MESH:D006988] (3)  Intracranial Hemorrhages [MESH:D020300] (3241)   Cerebral Hemorrhage [MESH:D002543] (2872)  Subarachnoid Hemorrhage [MESH:D013345] (1081)  Inflammation [MESH:D007249] (5241)   Systemic Inflammatory Response Syndrome [MESH:D018746] (3563)   Sepsis [MESH:D018805] (3562)  Menstruation Disturbances [MESH:D008599] (926)   Menorrhagia [MESH:D008595] (14)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Signs and Symptoms [MESH:D012816] (10659)   Neurologic Manifestations [MESH:D009461] (8702)   Pain [MESH:D010146] (3869)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Confusion [MESH:D003221] (284)   Delirium [MESH:D003693] (173)  Consciousness Disorders [MESH:D003244] (677)   Unconsciousness [MESH:D014474] (657)   Syncope [MESH:D013575] (128)  Perceptual Disorders [MESH:D010468] (343)   Hallucinations [MESH:D006212] (251)  Sensation Disorders [MESH:D012678] (5009)   Dizziness [MESH:D004244] (289)  Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Pain [MESH:D010146] (4511)   Chest Pain [MESH:D002637] (2642)   Angina Pectoris [MESH:D000787] (2568)   Acute Coronary Syndrome [MESH:D054058] (2286) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug Hypersensitivity [MESH:D004342] (4001)  Substance-Related Disorders [MESH:D019966] (6308)   Cocaine-Related Disorders [MESH:D019970] (3054)  Substance Withdrawal Syndrome [MESH:D013375] (2956) C26. Wounds and Injuries  C26. Wounds and Injuries  Wounds and Injuries [MESH:D014947] (5171)   Craniocerebral Trauma [MESH:D006259] (3523)   Brain Injuries [MESH:D001930] (3431)  Facial Injuries [MESH:D005151] (23)   Eye Injuries [MESH:D005131] (13)  Radiation Injuries [MESH:D011832] (2718)   Radiation Injuries, Experimental [MESH:D011833] (2662)  Trauma, Nervous System [MESH:D020196] (3535)   Craniocerebral Trauma [MESH:D006259] (3507)   Brain Injuries [MESH:D001930] (3431) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Carboxylic Acids [MESH:D002264] (13103)   Acids, Acyclic [MESH:D000144] (7142)   Caproates [MESH:D002208] (178)   Aminocaproates [MESH:D000614] (47)   Aminocaproic Acid [MESH:D015119] (3) D12. Amino Acids, Peptides, and Proteins  D12. Amino Acids, Peptides, and Proteins  Amino Acids [MESH:D000596] (5544)   Aminocaproates [MESH:D000614] (67)   Aminocaproic Acid [MESH:D015119] (3)