Item 1 of 47 (back to results) next   fenamic acid C001209               MeSH Unique Identifier: C001209 Scope Notes: Has chloride and potabetaium channel-blocking activity Chemical – Gene Interaction Note 1: Fenamic acid analog results in decreased activity of AKR1C1 protein Note 2: Fenamic acid analog results in decreased activity of AKR1C2 protein Click here for more information

Current search: C17. Skin and Connective Tissue Diseases: Skin Diseases [MESH:D012871] > Sweat Gland Diseases [MESH:D013543] > Hypohidrosis [MESH:D007007] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Aldo-keto reductases [HGNC:AKR] (282)   aldo-keto reductase family 1, member C1 [HGNC:AKR1C1] (148)  aldo-keto reductase family 1, member C2 [HGNC:AKR1C2] (134)  aldo-keto reductase family 1, member C3 [HGNC:AKR1C3] (128)  ATP-binding cassette transporters [HGNC:ABC] (821)   ATP-binding cassette transporters, subfamily C [HGNC:ABCC] (458)   ATP-binding cassette, sub-family C (CFTR/MRP), member 7 [HGNC:CFTR] (131)  Cystic fibrosis transmembrane conductance regulators [HGNC:CFTR] (131)   cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) [HGNC:CFTR] (131) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   cotreatment (1499)  Decreases (5154)   activity (2549)  reaction (3393)  Increases (5571)   activity (2865)  transport (399) A. Anatomy  A. Anatomy  Urogenital System [MESH:D014566] (986)   Genitalia [MESH:D005835] (400)   Genitalia, Male [MESH:D005837] (297)   Vas Deferens [MESH:D014649] (195)   Congenital bilateral aplasia of vas deferens [MESH:C535984] (194) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Cysts [MESH:D003560] (2625)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Carcinoma [MESH:D002277] (7263)   Adenocarcinoma [MESH:D000230] (6565)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms by Site [MESH:D009371] (9169)   Digestive System Neoplasms [MESH:D004067] (7487)   Gastrointestinal Neoplasms [MESH:D005770] (6452)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Head and Neck Neoplasms [MESH:D006258] (4612)   Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Mouth Neoplasms [MESH:D009062] (2263)   Tongue Neoplasms [MESH:D014062] (1518)  Skin Neoplasms [MESH:D012878] (2992)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Female [MESH:D005833] (2540)   Uterine Neoplasms [MESH:D014594] (2431)   Endometrial Neoplasms [MESH:D016889] (1987)  Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Neoplastic Processes [MESH:D009385] (5317)   Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Joint Diseases [MESH:D007592] (4657)   Arthritis [MESH:D001168] (4416)   Osteoarthritis [MESH:D010003] (1743)  Rheumatic Diseases [MESH:D012216] (4032)   Osteoarthritis [MESH:D010003] (1743) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Gastrointestinal Diseases [MESH:D005767] (7443)   Esophageal Diseases [MESH:D004935] (4255)   Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Stomach Diseases [MESH:D013272] (5325)   Stomach Neoplasms [MESH:D013274] (4942)  Liver Diseases [MESH:D008107] (8167)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Pancreatic Diseases [MESH:D010182] (4453)   Cystic Fibrosis [MESH:D003550] (760)  Pancreatitis [MESH:D010195] (1924)   Pancreatitis, Chronic [MESH:D050500] (276)   Hereditary pancreatitis [MESH:C537262] (234) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Mouth Diseases [MESH:D009059] (4783)   Mouth Neoplasms [MESH:D009062] (2263)   Tongue Neoplasms [MESH:D014062] (1518)  Tongue Diseases [MESH:D014060] (1544)   Tongue Neoplasms [MESH:D014062] (1518) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Bronchial Diseases [MESH:D001982] (4382)   Bronchiectasis [MESH:D001987] (1792)   Bronchiectasis With Or Without Elevated Sweat Chloride 1 [MESH:C567618] (217)  Lung Diseases [MESH:D008171] (7249)   Cystic Fibrosis [MESH:D003550] (760)  Lung Neoplasms [MESH:D008175] (6012)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Nose Diseases [MESH:D009668] (1504)   Rhinitis [MESH:D012220] (1134)  Paranasal Sinus Diseases [MESH:D010254] (476)   Sinusitis [MESH:D012852] (469)  Respiratory Hypersensitivity [MESH:D012130] (4401)   Ige Responsiveness, Atopic [MESH:C564133] (267)  Respiratory Tract Infections [MESH:D012141] (3926)   Rhinitis [MESH:D012220] (766)  Sinusitis [MESH:D012852] (469)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540) C09. Otorhinolaryngologic Diseases  C09. Otorhinolaryngologic Diseases  Otorhinolaryngologic Diseases [MESH:D010038] (3827)   Nose Diseases [MESH:D009668] (1504)   Rhinitis [MESH:D012220] (1134)  Paranasal Sinus Diseases [MESH:D010254] (476)   Sinusitis [MESH:D012852] (469) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Congenital bilateral aplasia of vas deferens [MESH:C535984] (194)  Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Infertility [MESH:D007246] (2909)   Infertility, Male [MESH:D007248] (2851)   Azoospermia [MESH:D053713] (1052)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Kidney Papillary Necrosis [MESH:D007681] (46)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)   Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Endometriosis [MESH:D004715] (2461)  Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Uterine Diseases [MESH:D014591] (2479)   Uterine Neoplasms [MESH:D014594] (2430)   Endometrial Neoplasms [MESH:D016889] (1984)  Urogenital Neoplasms [MESH:D014565] (5792)   Genital Neoplasms, Female [MESH:D005833] (3810)   Uterine Neoplasms [MESH:D014594] (2433)   Endometrial Neoplasms [MESH:D016889] (1989)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Kidney Papillary Necrosis [MESH:D007681] (46)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)   Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Abnormalities, Multiple [MESH:D000015] (3192)   Ectodermal Dysplasia [MESH:D004476] (938)   Naegeli syndrome [MESH:C538331] (38)  Skin Abnormalities [MESH:D012868] (1723)   Ectodermal Dysplasia [MESH:D004476] (958)   Naegeli syndrome [MESH:C538331] (38)  Epidermolysis Bullosa [MESH:D004820] (260)   Epidermolysis Bullosa Simplex [MESH:D016110] (140)   Epidermolysis Bullosa Simplex, Autosomal Recessive [MESH:C563408] (38)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Cystic Fibrosis [MESH:D003550] (760)  Skin Diseases, Genetic [MESH:D012873] (3456)   Ectodermal Dysplasia [MESH:D004476] (958)   Naegeli syndrome [MESH:C538331] (38)  Epidermolysis Bullosa [MESH:D004820] (259)   Epidermolysis Bullosa Simplex [MESH:D016110] (140)   Epidermolysis Bullosa Simplex, Autosomal Recessive [MESH:C563408] (38)  Keratoderma, Palmoplantar [MESH:D007645] (287)   Naegeli syndrome [MESH:C538331] (38)  Infant, Newborn, Diseases [MESH:D007232] (3064)   Cystic Fibrosis [MESH:D003550] (760) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Skin Diseases [MESH:D012871] (8774)   Hair Diseases [MESH:D006201] (1891)   Hypotrichosis [MESH:D007039] (1513)   Alopecia [MESH:D000505] (1453)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Keratosis [MESH:D007642] (1941)   Keratoderma, Palmoplantar [MESH:D007645] (287)   Naegeli syndrome [MESH:C538331] (38)  Nail Diseases [MESH:D009260] (203)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Pigmentation Disorders [MESH:D010859] (1215)   Hyperpigmentation [MESH:D017495] (523)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Skin Abnormalities [MESH:D012868] (1709)   Ectodermal Dysplasia [MESH:D004476] (958)   Naegeli syndrome [MESH:C538331] (38)  Epidermolysis Bullosa [MESH:D004820] (260)   Epidermolysis Bullosa Simplex [MESH:D016110] (140)   Epidermolysis Bullosa Simplex, Autosomal Recessive [MESH:C563408] (38)  Skin Diseases, Genetic [MESH:D012873] (3481)   Ectodermal Dysplasia [MESH:D004476] (958)   Naegeli syndrome [MESH:C538331] (38)  Epidermolysis Bullosa [MESH:D004820] (260)   Epidermolysis Bullosa Simplex [MESH:D016110] (140)   Epidermolysis Bullosa Simplex, Autosomal Recessive [MESH:C563408] (38)  Keratoderma, Palmoplantar [MESH:D007645] (287)   Naegeli syndrome [MESH:C538331] (38)  Skin Diseases, Vesiculobullous [MESH:D012872] (1754)   Blister [MESH:D001768] (93)  Epidermolysis Bullosa [MESH:D004820] (260)   Epidermolysis Bullosa Simplex [MESH:D016110] (140)   Epidermolysis Bullosa Simplex, Autosomal Recessive [MESH:C563408] (38)  Skin Neoplasms [MESH:D012878] (2991)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Sweat Gland Diseases [MESH:D013543] (231)   Hypohidrosis [MESH:D007007] (47)   Naegeli syndrome [MESH:C538331] (38) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Nutrition Disorders [MESH:D009748] (4945)   Overnutrition [MESH:D044343] (4463)   Obesity [MESH:D009765] (4462) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Gonadal Disorders [MESH:D006058] (5088)   Ovarian Diseases [MESH:D010049] (4253)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Hypersensitivity [MESH:D006967] (5873)   Hypersensitivity, Immediate [MESH:D006969] (4980)   Respiratory Hypersensitivity [MESH:D012130] (4250)   Ige Responsiveness, Atopic [MESH:C564133] (267) C22. Animal Diseases  C22. Animal Diseases  Animal Diseases [MESH:D000820] (3656)   Disease Models, Animal [MESH:D004195] (2058) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Blister [MESH:D001768] (93)  Alopecia [MESH:D000505] (1383)   Dermatopathia pigmentosa reticularis [MESH:C535374] (38)  Hernia [MESH:D006547] (2825)   Hernia, Diaphragmatic [MESH:D006548] (2647)  Pathologic Processes [MESH:D010335] (9863)   Necrosis [MESH:D009336] (4019)  Neoplastic Processes [MESH:D009385] (5317)   Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389)  Signs and Symptoms [MESH:D012816] (10659)   Body Weight [MESH:D001835] (4972)   Overweight [MESH:D050177] (4455)   Obesity [MESH:D009765] (4454)  Urological Manifestations [MESH:D020924] (3532)   Proteinuria [MESH:D011507] (3293) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Substance-Related Disorders [MESH:D019966] (6308)  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Poisoning [MESH:D011041] (6703)   Drug-Induced Liver Injury [MESH:D056486] (4936) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Carboxylic Acids [MESH:D002264] (13103)   Acids, Carbocyclic [MESH:D000146] (5074)   Benzoates [MESH:D001565] (3081)   Aminobenzoates [MESH:D062365] (480)   ortho-Aminobenzoates [MESH:D062367] (164)  Hydrocarbons [MESH:D006838] (35762)   Hydrocarbons, Cyclic [MESH:D006844] (22983)   Hydrocarbons, Aromatic [MESH:D006841] (19108)   Benzene Derivatives [MESH:D001555] (10684)   Benzoates [MESH:D001565] (3081)   Aminobenzoates [MESH:D062365] (480)   ortho-Aminobenzoates [MESH:D062367] (164) D27. Chemical Actions and Uses  D27. Chemical Actions and Uses  Pharmacologic Actions [MESH:D020228] (2566)   Physiological Effects of Drugs [MESH:D045505] (1186)   Peripheral Nervous System Agents [MESH:D018373] (275)   Sensory System Agents [MESH:D018689] (193)   Analgesics [MESH:D000700] (173)   Analgesics, Non-Narcotic [MESH:D018712] (120)   Anti-Inflammatory Agents, Non-Steroidal [MESH:D000894] (115)  Therapeutic Uses [MESH:D045506] (1611)   Anti-Inflammatory Agents [MESH:D000893] (128)   Anti-Inflammatory Agents, Non-Steroidal [MESH:D000894] (115)  Antirheumatic Agents [MESH:D018501] (129)   Anti-Inflammatory Agents, Non-Steroidal [MESH:D000894] (115)  Cardiovascular Agents [MESH:D002317] (271)   Calcium Channel Blockers [MESH:D002121] (34)