Item 4 of 881 (back to results) previous next   4-ipomeanol C001470               MeSH Unique Identifier: C001470 Scope Notes: Lung-toxic furanoterpenoid produced in moldy sweet potatoes in response to fungus infection Chemical – Gene Interaction Note 1: CYP1A2 protein results in increased activity of 4-ipomeanol Note 2: CYP2C19 protein results in increased activity of 4-ipomeanol Click here for more information

Current search: C18. Nutritional and Metabolic Diseases: Metabolic Diseases [MESH:D008659] > Porphyrias [MESH:D011164] > Porphyrias, Hepatic [MESH:D017094] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Cytochrome P450s [HGNC:CYP] (1673)   cytochrome P450, family 01, subfamily A, polypeptide 02 [HGNC:CYP1A2] (466)  cytochrome P450, family 02, subfamily C, polypeptide 19 [HGNC:CYP2C19] (172)  cytochrome P450, family 02, subfamily D, polypeptide 06 [HGNC:CYP2D6] (200)  cytochrome P450, family 03, subfamily A, polypeptide 04 [HGNC:CYP3A4] (612) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Increases (5571)   activity (2865) C02. Virus Diseases  C02. Virus Diseases  Virus Diseases [MESH:D014777] (4544)   Hepatitis, Viral, Human [MESH:D006525] (1766)   Hepatitis C [MESH:D006526] (1627)  RNA Virus Infections [MESH:D012327] (4215)   Flaviviridae Infections [MESH:D018178] (1656)   Hepatitis C [MESH:D006526] (1627) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742)   Neoplasms, Connective Tissue [MESH:D009372] (3626)   Neoplasms, Bone Tissue [MESH:D018213] (2217)   Osteosarcoma [MESH:D012516] (2175)  Sarcoma [MESH:D012509] (4246)   Osteosarcoma [MESH:D012516] (2175)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Carcinoma [MESH:D002277] (7263)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Neoplasms by Site [MESH:D009371] (9169)   Breast Neoplasms [MESH:D001943] (6077)  Digestive System Neoplasms [MESH:D004067] (7487)   Gastrointestinal Neoplasms [MESH:D005770] (6452)   Intestinal Neoplasms [MESH:D007414] (5358)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Liver Neoplasms, Experimental [MESH:D008114] (2837)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Neoplasms, Experimental [MESH:D009374] (5218)   Liver Neoplasms, Experimental [MESH:D008114] (2837) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Muscular Diseases [MESH:D009135] (4071)   Muscle Rigidity [MESH:D009127] (617) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Liver Neoplasms, Experimental [MESH:D008114] (2837)  Gastrointestinal Diseases [MESH:D005767] (7443)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Intestinal Diseases [MESH:D007410] (6206)   Colonic Diseases [MESH:D003108] (5564)   Colorectal Neoplasms [MESH:D015179] (5282)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Rectal Diseases [MESH:D012002] (4596)   Colorectal Neoplasms [MESH:D015179] (4534)  Liver Diseases [MESH:D008107] (8167)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Hepatomegaly [MESH:D006529] (1169)  Hepatitis [MESH:D006505] (3883)   Hepatitis, Viral, Human [MESH:D006525] (1766)   Hepatitis C [MESH:D006526] (1627)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Experimental [MESH:D008106] (4589)  Liver Neoplasms [MESH:D008113] (6048)   Liver Neoplasms, Experimental [MESH:D008114] (2837)  Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Lung Injury [MESH:D055370] (3688)  Lung Neoplasms [MESH:D008175] (6012)  Lung Diseases, Obstructive [MESH:D008173] (4697)   Pulmonary Disease, Chronic Obstructive [MESH:D029424] (3564)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Basal Ganglia Diseases [MESH:D001480] (4268)   Parkinsonian Disorders [MESH:D020734] (4009)   Parkinson Disease [MESH:D010300] (3595)  Dementia [MESH:D003704] (4498)   Alzheimer Disease [MESH:D000544] (4275)  Epilepsy [MESH:D004827] (6274)   Epilepsy, Generalized [MESH:D004829] (1431)   Epilepsy, Tonic-Clonic [MESH:D004830] (1042)  Movement Disorders [MESH:D009069] (4823)   Parkinsonian Disorders [MESH:D020734] (4009)   Parkinson Disease [MESH:D010300] (3595)  Nervous System Malformations [MESH:D009421] (3354)   Neural Tube Defects [MESH:D009436] (2143)  Neurodegenerative Diseases [MESH:D019636] (6613)   Parkinson Disease [MESH:D010300] (3595)  Tauopathies [MESH:D024801] (4289)   Alzheimer Disease [MESH:D000544] (4275)  Neurologic Manifestations [MESH:D009461] (8964)   Dyskinesias [MESH:D020820] (3365)   Dystonia [MESH:D004421] (848)  Tremor [MESH:D014202] (840)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Consciousness Disorders [MESH:D003244] (680)   Unconsciousness [MESH:D014474] (660)   Coma [MESH:D003128] (524)  Neuromuscular Manifestations [MESH:D020879] (2130)   Muscle Hypertonia [MESH:D009122] (775)   Muscle Rigidity [MESH:D009127] (617)  Neuromuscular Diseases [MESH:D009468] (7336)   Peripheral Nervous System Diseases [MESH:D010523] (6151)  Neurotoxicity Syndromes [MESH:D020258] (4570)   Heavy Metal Poisoning, Nervous System [MESH:D020260] (2912)   Manganese Poisoning [MESH:D020149] (2214) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Nephritis [MESH:D009393] (4236)   Nephritis, Interstitial [MESH:D009395] (1927)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4374)   Urinary Bladder Neoplasms [MESH:D001749] (4079) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Primary Ovarian Insufficiency [MESH:D016649] (270)  Urogenital Neoplasms [MESH:D014565] (5792)   Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Nephritis [MESH:D009393] (4236)   Nephritis, Interstitial [MESH:D009395] (1927)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4375)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Pregnancy Complications [MESH:D011248] (4768)   Prenatal Injuries [MESH:D049188] (1314)   Prenatal Exposure Delayed Effects [MESH:D011297] (870) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Z. Exceptions (2667)   Not Fully Specified [NFS] (2667)  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Arrhythmias, Cardiac [MESH:D001145] (4679)   Bradycardia [MESH:D001919] (1899)  Tachycardia [MESH:D013610] (3339)   Tachycardia, Ventricular [MESH:D017180] (1386)   Torsades de Pointes [MESH:D016171] (880)  Vascular Diseases [MESH:D014652] (8691)   Embolism and Thrombosis [MESH:D016769] (3374)   Thrombosis [MESH:D013927] (3101) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Methemoglobinemia [MESH:D008708] (850)  Lymphatic Diseases [MESH:D008206] (5167)   Splenic Diseases [MESH:D013158] (1323) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Nervous System Malformations [MESH:D009421] (3354)   Neural Tube Defects [MESH:D009436] (2143)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Metabolism, Inborn Errors [MESH:D008661] (6032)   Drug Metabolism, Poor, CYP2C19-Related [MESH:C563703] (182)  Drug Metabolism, Poor, CYP2D6-Related [MESH:C563835] (220)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Skin Diseases, Genetic [MESH:D012873] (3456)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Skin Diseases [MESH:D012871] (8774)   Breast Diseases [MESH:D001941] (6148)   Breast Neoplasms [MESH:D001943] (6077)  Skin Diseases, Genetic [MESH:D012873] (3481)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Glucose Metabolism Disorders [MESH:D044882] (6122)   Diabetes Mellitus [MESH:D003920] (5891)   Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Metabolism, Inborn Errors [MESH:D008661] (6028)   Drug Metabolism, Poor, CYP2C19-Related [MESH:C563703] (182)  Drug Metabolism, Poor, CYP2D6-Related [MESH:C563835] (220)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Porphyria Cutanea Tarda [MESH:D017119] (766) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Diabetes Mellitus [MESH:D003920] (6159)   Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Gonadal Disorders [MESH:D006058] (5088)   Ovarian Diseases [MESH:D010049] (4253)   Primary Ovarian Insufficiency [MESH:D016649] (270) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Atrophy [MESH:D001284] (2603)  Hypertrophy [MESH:D006984] (4476)   Hepatomegaly [MESH:D006529] (1169)  Splenomegaly [MESH:D013163] (1258)  Pathologic Processes [MESH:D010335] (9863)   Growth Disorders [MESH:D006130] (2438)  Arrhythmias, Cardiac [MESH:D001145] (4658)   Bradycardia [MESH:D001919] (1899)  Tachycardia [MESH:D013610] (3339)   Tachycardia, Ventricular [MESH:D017180] (1386)   Torsades de Pointes [MESH:D016171] (880)  Signs and Symptoms [MESH:D012816] (10659)   Body Weight [MESH:D001835] (4972)   Body Weight Changes [MESH:D001836] (3206)   Weight Gain [MESH:D015430] (2595)  Neurologic Manifestations [MESH:D009461] (8702)   Dyskinesias [MESH:D020820] (3285)   Dystonia [MESH:D004421] (848)  Tremor [MESH:D014202] (840)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Consciousness Disorders [MESH:D003244] (677)   Unconsciousness [MESH:D014474] (657)   Coma [MESH:D003128] (492)  Neuromuscular Manifestations [MESH:D020879] (2130)   Muscle Hypertonia [MESH:D009122] (775)   Muscle Rigidity [MESH:D009127] (617) C24. Occupational Diseases  C24. Occupational Diseases  Occupational Diseases [MESH:D009784] (3402)  Z. Exceptions (1530)   Not Fully Specified [NFS] (1530) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Poisoning [MESH:D011041] (6703)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Manganese Poisoning [MESH:D020149] (2214)  Substance-Related Disorders [MESH:D019966] (6308)   Amphetamine-Related Disorders [MESH:D019969] (2858) C26. Wounds and Injuries  C26. Wounds and Injuries  Wounds and Injuries [MESH:D014947] (5171)   Thoracic Injuries [MESH:D013898] (1831)   Lung Injury [MESH:D055370] (1814) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Hydrocarbons [MESH:D006838] (35762)   Terpenes [MESH:D013729] (10347) D27. Chemical Actions and Uses  D27. Chemical Actions and Uses  Pharmacologic Actions [MESH:D020228] (2566)   Therapeutic Uses [MESH:D045506] (1611)   Antineoplastic Agents [MESH:D000970] (319)