Item 33 of 789 (back to results) previous next   phorbol-12,13-didecanoate C008876               MeSH Unique Identifier: C008876 Chemical – Gene Interaction Note 1: Phorbol-12,13-didecanoate results in increased secretion of MMP1 protein Note 2: Phorbol-12,13-didecanoate binds to and results in increased activity of TRPV4 protein Click here for more information

Current search: C18. Nutritional and Metabolic Diseases: Metabolic Diseases [MESH:D008659] > Water-Electrolyte Imbalance [MESH:D014883] > Hyponatremia [MESH:D007010] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Ankyrin repeat domain containing [HGNC:ANKRD] (566)   transient receptor potential cation channel, subfamily V, member 4 [HGNC:TRPV4] (10)  Transient receptor potential cation channels [HGNC:TRP] (169)   transient receptor potential cation channel, subfamily V, member 4 [HGNC:TRPV4] (10) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   binding (2423)  Increases (5571)   activity (2865)  import (65)  reaction (1574)  secretion (901) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Site [MESH:D009371] (9169)   Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Bone Diseases [MESH:D001847] (5801)   Bone Diseases, Developmental [MESH:D001848] (3315)   Dwarfism [MESH:D004392] (778)   Parastremmatic dwarfism [MESH:C537172] (39)  Metatropic dwarfism [MESH:C537356] (39)  Osteochondrodysplasias [MESH:D010009] (2440)   Spondylometaphyseal dysplasia, Kozlowski type [MESH:C535797] (118)  Metatropic dwarfism [MESH:C537356] (39)  Brachyolmia Type 3 [MESH:C562963] (39)  Spinal Diseases [MESH:D013122] (2485)   Spinal Curvatures [MESH:D013121] (742)   Kyphosis [MESH:D007738] (637)   Parastremmatic dwarfism [MESH:C537172] (39)  Scoliosis [MESH:D012600] (194)   Parastremmatic dwarfism [MESH:C537172] (39)  Joint Diseases [MESH:D007592] (4657)   Arthritis [MESH:D001168] (4416)   Arthritis, Experimental [MESH:D001169] (3142)  Osteoarthritis [MESH:D010003] (1743)  Rheumatic Diseases [MESH:D012216] (4032)   Osteoarthritis [MESH:D010003] (1743) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Gastrointestinal Diseases [MESH:D005767] (7443)   Esophageal Diseases [MESH:D004935] (4255)   Deglutition Disorders [MESH:D003680] (1538)   Esophageal Motility Disorders [MESH:D015154] (1489)   Gastroesophageal Reflux [MESH:D005764] (1465)  Liver Diseases [MESH:D008107] (8167)   Fatty Liver [MESH:D005234] (3584)   Non-alcoholic Fatty Liver Disease [MESH:C541083] (1567)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Experimental [MESH:D008106] (4589) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Mouth Diseases [MESH:D009059] (4783)   Oral Submucous Fibrosis [MESH:D009914] (2432)  Salivary Gland Diseases [MESH:D012466] (1213)   Sialorrhea [MESH:D012798] (252) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Bronchial Diseases [MESH:D001982] (4382)   Bronchial Hyperreactivity [MESH:D016535] (1357)  Lung Diseases [MESH:D008171] (7249)   Hypertension, Pulmonary [MESH:D006976] (2000)  Pulmonary Fibrosis [MESH:D011658] (3140)  Lung Diseases, Obstructive [MESH:D008173] (4697)   Pulmonary Disease, Chronic Obstructive [MESH:D029424] (3564)  Lung Neoplasms [MESH:D008175] (6012)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Headache Disorders [MESH:D020773] (2337)   Headache Disorders, Primary [MESH:D051270] (2327)   Migraine Disorders [MESH:D008881] (2318)   Migraine without Aura [MESH:D020326] (408)  Spinal Cord Diseases [MESH:D013118] (4376)   Muscular Atrophy, Spinal [MESH:D009134] (850)  Nervous System Malformations [MESH:D009421] (3354)   Hereditary Sensory and Motor Neuropathy [MESH:D015417] (899)   Charcot-Marie-Tooth Disease [MESH:D002607] (627)   Hereditary Motor And Sensory Neuropathy, Type IIC [MESH:C565261] (39)  Neurodegenerative Diseases [MESH:D019636] (6613)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3243)   Hereditary Sensory and Motor Neuropathy [MESH:D015417] (899)   Charcot-Marie-Tooth Disease [MESH:D002607] (627)   Hereditary Motor And Sensory Neuropathy, Type IIC [MESH:C565261] (39)  Motor Neuron Disease [MESH:D016472] (3670)   Muscular Atrophy, Spinal [MESH:D009134] (850)  Neurologic Manifestations [MESH:D009461] (8964)   Neurogenic Inflammation [MESH:D020078] (2246)  Dyskinesias [MESH:D020820] (3365)   Catalepsy [MESH:D002375] (1429)  Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Memory Disorders [MESH:D008569] (3233)   Amnesia [MESH:D000647] (1911)  Intellectual Disability [MESH:D008607] (3054)   Parastremmatic dwarfism [MESH:C537172] (39)  Down Syndrome [MESH:D004314] (1287)  Pain [MESH:D010146] (3875)   Neuralgia [MESH:D009437] (2074)  Sensation Disorders [MESH:D012678] (5011)   Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Neuromuscular Diseases [MESH:D009468] (7336)   Muscular Atrophy, Spinal [MESH:D009134] (377)  Motor Neuron Disease [MESH:D016472] (3670)   Muscular Atrophy, Spinal [MESH:D009134] (850)  Peripheral Nervous System Diseases [MESH:D010523] (6151)   Neuralgia [MESH:D009437] (2078)  Mononeuropathies [MESH:D020422] (604)   Sciatic Neuropathy [MESH:D020426] (477)  Polyneuropathies [MESH:D011115] (1134)   Hereditary Sensory and Motor Neuropathy [MESH:D015417] (899)   Charcot-Marie-Tooth Disease [MESH:D002607] (627)   Hereditary Motor And Sensory Neuropathy, Type IIC [MESH:C565261] (39)  Sleep Disorders [MESH:D012893] (2050)   Dyssomnias [MESH:D020920] (1417)   Sleep Disorders, Intrinsic [MESH:D020919] (1270)   Disorders of Excessive Somnolence [MESH:D006970] (581)   Narcolepsy [MESH:D009290] (478) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Corneal Diseases [MESH:D003316] (1445)  Ocular Hypertension [MESH:D009798] (1630) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Diseases [MESH:D014570] (7792)   Urination Disorders [MESH:D014555] (3598) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Urologic Diseases [MESH:D014570] (7793)   Urination Disorders [MESH:D014555] (3598) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Arrhythmias, Cardiac [MESH:D001145] (4679)   Bradycardia [MESH:D001919] (1899)  Vascular Diseases [MESH:D014652] (8691)   Aneurysm [MESH:D000783] (1886)  Hyperemia [MESH:D006940] (2372)  Hypertension [MESH:D006973] (5655)  Hypotension [MESH:D007022] (4045)  Arterial Occlusive Diseases [MESH:D001157] (4520)   Arteriosclerosis [MESH:D001161] (4466)   Atherosclerosis [MESH:D050197] (4188) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Abnormalities, Multiple [MESH:D000015] (3192)   Down Syndrome [MESH:D004314] (1287)  Chromosome Disorders [MESH:D025063] (2030)   Down Syndrome [MESH:D004314] (1287)  Nervous System Malformations [MESH:D009421] (3354)   Hereditary Sensory and Motor Neuropathy [MESH:D015417] (899)   Charcot-Marie-Tooth Disease [MESH:D002607] (627)   Hereditary Motor And Sensory Neuropathy, Type IIC [MESH:C565261] (39)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Chromosome Disorders [MESH:D025063] (2030)   Down Syndrome [MESH:D004314] (1287)  Dwarfism [MESH:D004392] (783)   Parastremmatic dwarfism [MESH:C537172] (39)  Metatropic dwarfism [MESH:C537356] (39)  Heredodegenerative Disorders, Nervous System [MESH:D020271] (3465)   Hereditary Sensory and Motor Neuropathy [MESH:D015417] (899)   Charcot-Marie-Tooth Disease [MESH:D002607] (627)   Hereditary Motor And Sensory Neuropathy, Type IIC [MESH:C565261] (39) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Skin Diseases [MESH:D012871] (8774)   Pruritus [MESH:D011537] (647)  Dermatitis [MESH:D003872] (4530)   Drug Eruptions [MESH:D003875] (2697) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Calcium Metabolism Disorders [MESH:D002128] (3634)   Hypercalcemia [MESH:D006934] (1999)  Water-Electrolyte Imbalance [MESH:D014883] (2790)   Hypercalcemia [MESH:D006934] (1999)  Hyponatremia [MESH:D007010] (789) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Dwarfism [MESH:D004392] (698)   Parastremmatic dwarfism [MESH:C537172] (39)  Metatropic dwarfism [MESH:C537356] (39) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Hypersensitivity [MESH:D006967] (5873)   Drug Hypersensitivity [MESH:D004342] (4000)   Drug Eruptions [MESH:D003875] (2695) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathologic Processes [MESH:D010335] (9863)   Extravasation of Diagnostic and Therapeutic Materials [MESH:D005119] (506)  Arrhythmias, Cardiac [MESH:D001145] (4658)   Bradycardia [MESH:D001919] (1899)  Inflammation [MESH:D007249] (5241)   Neurogenic Inflammation [MESH:D020078] (2246)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Signs and Symptoms [MESH:D012816] (10659)   Edema [MESH:D004487] (3726)  Neurologic Manifestations [MESH:D009461] (8702)   Dyskinesias [MESH:D020820] (3285)   Catalepsy [MESH:D002375] (1429)  Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Memory Disorders [MESH:D008569] (3233)   Amnesia [MESH:D000647] (1911)  Intellectual Disability [MESH:D008607] (1476)   Parastremmatic dwarfism [MESH:C537172] (39)  Pain [MESH:D010146] (3869)   Neuralgia [MESH:D009437] (2074)  Sensation Disorders [MESH:D012678] (5009)   Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Pain [MESH:D010146] (4511)   Neuralgia [MESH:D009437] (2074)  Skin Manifestations [MESH:D012877] (1250)   Pruritus [MESH:D011537] (648) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug Hypersensitivity [MESH:D004342] (4001)   Drug Eruptions [MESH:D003875] (2697) C26. Wounds and Injuries  C26. Wounds and Injuries  Z. Exceptions (2454)   Not Fully Specified [NFS] (2454)  Wounds and Injuries [MESH:D014947] (5171)   Extravasation of Diagnostic and Therapeutic Materials [MESH:D005119] (506) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Hydrocarbons [MESH:D006838] (35762)   Terpenes [MESH:D013729] (10347)   Diterpenes [MESH:D004224] (2867)   Phorbols [MESH:D010704] (75)   Phorbol Esters [MESH:D010703] (57) F. Psychiatry and Psychology  F. Psychiatry and Psychology  Behavior and Behavior Mechanisms [MESH:D001520] (1594)   Neurobehavioral Manifestations [MESH:D019954] (1206)   Intellectual Disability [MESH:D008607] (1109)   Parastremmatic dwarfism [MESH:C537172] (39)  Mental Disorders [MESH:D001523] (2063)   Mental Disorders Diagnosed in Childhood [MESH:D019952] (1245)   Intellectual Disability [MESH:D008607] (1109)   Parastremmatic dwarfism [MESH:C537172] (39)