Item 1 of 128 (back to results) next   4-nitrobenzylthioinosine C001789               MeSH Unique Identifier: C001789 Scope Notes: Inhibitor of nucleoside transport; acts on ENT1 Chemical – Gene Interaction Note 1: 4-nitrobenzylthioinosine inhibits the reaction [[SLC29A1 protein co-treated with SLC29A2 protein] results in increased uptake of Uridine] Note 2: 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in decreased susceptibility to Fluorouracil] Click here for more information

Current search: C25. Chemically-Induced Disorders: Substance-Related Disorders [MESH:D019966] > Alcohol-Related Disorders [MESH:D019973] > Alcohol-Induced Disorders [MESH:D020751] > Alcohol-Induced Disorders, Nervous System [MESH:D020268] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Solute carriers [HGNC:SLC] (716)   solute carrier family 29 (equilibrative nucleoside transporter), member 1 [HGNC:SLC29A1] (34) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   cotreatment (1499)  Decreases (5154)   reaction (3393)  response to substance (713)  Increases (5571)   reaction (1574)  uptake (378) 4. Semantic Terms  4. Semantic Terms  Entity [STY:T071] (48056)   Physical Object [STY:T072] (47583)   Substance [STY:T167] (46174)   Chemical [STY:T103] (46110)   Chemical Viewed Functionally [STY:T120] (28747)   Pharmacologic Substance [STY:T121] (11019)  Chemical Viewed Structurally [STY:T104] (44741)   Organic Chemical [STY:T109] (44144)   Nucleic Acid, Nucleoside, or Nucleotide [STY:T114] (1401) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126)   Neuroectodermal Tumors [MESH:D017599] (5066)   Neuroendocrine Tumors [MESH:D018358] (3633)   Melanoma [MESH:D008545] (3508)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Carcinoma [MESH:D002277] (7263)   Adenocarcinoma [MESH:D000230] (6565)  Carcinoma, Small Cell [MESH:D018288] (1317)  Neoplasms, Nerve Tissue [MESH:D009380] (5201)   Neuroectodermal Tumors [MESH:D017599] (5059)   Neuroendocrine Tumors [MESH:D018358] (3625)   Melanoma [MESH:D008545] (3508)  Nevi and Melanomas [MESH:D018326] (3572)   Melanoma [MESH:D008545] (3508)  Neoplasms by Site [MESH:D009371] (9169)   Skin Neoplasms [MESH:D012878] (2992)  Digestive System Neoplasms [MESH:D004067] (7487)   Pancreatic Neoplasms [MESH:D010190] (3820)  Endocrine Gland Neoplasms [MESH:D004701] (4925)   Pancreatic Neoplasms [MESH:D010190] (3820)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Metastasis [MESH:D009362] (4441) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Pancreatic Neoplasms [MESH:D010190] (3820)  Liver Diseases [MESH:D008107] (8167)   Liver Cirrhosis [MESH:D008103] (5542)  Pancreatic Diseases [MESH:D010182] (4453)   Pancreatic Neoplasms [MESH:D010190] (3820) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Lung Neoplasms [MESH:D008175] (6012)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Neurologic Manifestations [MESH:D009461] (8964)   Pain [MESH:D010146] (3875)  Seizures [MESH:D012640] (4514)   Alcohol Withdrawal Seizures [MESH:D020270] (64)  Neurotoxicity Syndromes [MESH:D020258] (4570)   Alcohol-Induced Disorders, Nervous System [MESH:D020268] (128)   Alcohol Withdrawal Seizures [MESH:D020270] (64) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Diseases [MESH:D014570] (7792)   Urination Disorders [MESH:D014555] (3598)  Kidney Diseases [MESH:D007674] (7242)   Hypertension, Renal [MESH:D006977] (698)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Urologic Diseases [MESH:D014570] (7793)   Urination Disorders [MESH:D014555] (3598)  Kidney Diseases [MESH:D007674] (7242)   Hypertension, Renal [MESH:D006977] (698)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Cardiovascular Abnormalities [MESH:D018376] (3153)   Heart Defects, Congenital [MESH:D006330] (2447)   Ductus Arteriosus, Patent [MESH:D004374] (325)  Heart Diseases [MESH:D006331] (8614)   Heart Failure [MESH:D006333] (4058)  Arrhythmias, Cardiac [MESH:D001145] (4679)   Atrial Fibrillation [MESH:D001281] (1053)   Atrial Fibrillation, Familial, 6 [MESH:C567400] (196)  Cardiomegaly [MESH:D006332] (4081)   Cardiomyopathy, Dilated [MESH:D002311] (1576)  Hypertrophy, Left Ventricular [MESH:D017379] (1430)  Cardiomyopathies [MESH:D009202] (5331)   Cardiomyopathy, Dilated [MESH:D002311] (1576)  Heart Defects, Congenital [MESH:D006330] (2443)   Ductus Arteriosus, Patent [MESH:D004374] (325)  Heart Valve Diseases [MESH:D006349] (3333)   Aortic Valve Insufficiency [MESH:D001022] (1002)  Myocardial Ischemia [MESH:D017202] (5787)   Myocardial Infarction [MESH:D009203] (4122)  Coronary Disease [MESH:D003327] (3439)   Coronary Stenosis [MESH:D023921] (1806)  Vascular Diseases [MESH:D014652] (8691)   Hypotension [MESH:D007022] (4045)  Hypertension [MESH:D006973] (5655)   Hypertension, Renal [MESH:D006977] (698)  Myocardial Ischemia [MESH:D017202] (5791)   Myocardial Infarction [MESH:D009203] (4151)  Coronary Disease [MESH:D003327] (3439)   Coronary Stenosis [MESH:D023921] (1806) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Cardiovascular Abnormalities [MESH:D018376] (3294)   Heart Defects, Congenital [MESH:D006330] (2611)   Ductus Arteriosus, Patent [MESH:D004374] (325) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Skin Diseases [MESH:D012871] (8774)   Skin Neoplasms [MESH:D012878] (2991) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Endocrine Gland Neoplasms [MESH:D004701] (4925)   Pancreatic Neoplasms [MESH:D010190] (3820) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Hernia [MESH:D006547] (2825)   Hernia, Diaphragmatic [MESH:D006548] (2647)  Hypertrophy [MESH:D006984] (4476)   Cardiomegaly [MESH:D006332] (3802)   Hypertrophy, Left Ventricular [MESH:D017379] (1430)  Pathologic Processes [MESH:D010335] (9863)   Arrhythmias, Cardiac [MESH:D001145] (4658)   Atrial Fibrillation [MESH:D001281] (1053)   Atrial Fibrillation, Familial, 6 [MESH:C567400] (196)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Metastasis [MESH:D009362] (4441)  Signs and Symptoms [MESH:D012816] (10659)   Pain [MESH:D010146] (4511)  Neurologic Manifestations [MESH:D009461] (8702)   Pain [MESH:D010146] (3869)  Signs and Symptoms, Respiratory [MESH:D012818] (2724)   Anoxia [MESH:D000860] (1698)  Hypercapnia [MESH:D006935] (264) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Poisoning [MESH:D011041] (6703)   Neurotoxicity Syndromes [MESH:D020258] (3323)   Alcohol-Induced Disorders, Nervous System [MESH:D020268] (128)   Alcohol Withdrawal Seizures [MESH:D020270] (64)  Substance-Related Disorders [MESH:D019966] (6308)   Alcohol-Related Disorders [MESH:D019973] (3869)   Alcohol-Induced Disorders [MESH:D020751] (3350)   Alcohol-Induced Disorders, Nervous System [MESH:D020268] (128)   Alcohol Withdrawal Seizures [MESH:D020270] (64)  Substance Withdrawal Syndrome [MESH:D013375] (2956)   Alcohol Withdrawal Seizures [MESH:D020270] (64) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Sulfur Compounds [MESH:D013457] (10450)   Thionucleosides [MESH:D013872] (112)   Thioinosine [MESH:D013868] (17) D03. Heterocyclic Compounds  D03. Heterocyclic Compounds  Heterocyclic Compounds [MESH:D006571] (56330)   Heterocyclic Compounds, 2-Ring [MESH:D006574] (24204)   Purines [MESH:D011687] (3899)   Purine Nucleosides [MESH:D011684] (1179)   Inosine [MESH:D007288] (86)   Thioinosine [MESH:D013868] (17) D13. Nucleic Acids, Nucleotides, and Nucleosides  D13. Nucleic Acids, Nucleotides, and Nucleosides  Nucleosides [MESH:D009705] (2984)   Purine Nucleosides [MESH:D011684] (1179)   Inosine [MESH:D007288] (86)   Thioinosine [MESH:D013868] (17)  Ribonucleosides [MESH:D012263] (1226)   Inosine [MESH:D007288] (86)   Thioinosine [MESH:D013868] (17)  Thionucleosides [MESH:D013872] (112)   Thioinosine [MESH:D013868] (17) D27. Chemical Actions and Uses  D27. Chemical Actions and Uses  Specialty Uses of Chemicals [MESH:D020313] (713)   Laboratory Chemicals [MESH:D019995] (233)   Indicators and Reagents [MESH:D007202] (196)   Affinity Labels [MESH:D000345] (15)