Note 1: Benzarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
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more general categories information about this item 2. Interaction: Human Genes and Chemicals 2. Interaction: Human Genes and Chemicals Decreases (5154) reaction (3393) Increases (5571) uptake (378) C06. Digestive System Diseases C06. Digestive System Diseases Digestive System Diseases [MESH:D004066] (9461) Liver Diseases [MESH:D008107] (8167) Drug-Induced Liver Injury [MESH:D056486] (4936) Hepatitis [MESH:D006505] (3883) Liver Cirrhosis [MESH:D008103] (5542) Hepatic Insufficiency [MESH:D048550] (2771) Liver Failure [MESH:D017093] (2768) End Stage Liver Disease [MESH:D058625] (108) Hepatic Encephalopathy [MESH:D006501] (1795) Liver Failure, Acute [MESH:D017114] (2404) C10. Nervous System Diseases C10. Nervous System Diseases Nervous System Diseases [MESH:D009422] (13325) Central Nervous System Diseases [MESH:D002493] (9745) Brain Diseases [MESH:D001927] (9294) Brain Diseases, Metabolic [MESH:D001928] (3351) Hepatic Encephalopathy [MESH:D006501] (1795) C12. Male Urogenital Diseases C12. Male Urogenital Diseases Male Urogenital Diseases [MESH:D052801] (8891) Urologic Diseases [MESH:D014570] (7792) Kidney Diseases [MESH:D007674] (7242) Renal Insufficiency [MESH:D051437] (4951) Acute Kidney Injury [MESH:D058186] (4142) Renal Tubular Transport, Inborn Errors [MESH:D015499] (1058) Renal hypouricemia [MESH:C537757] (71) Urolithiasis [MESH:D052878] (585) Urinary Calculi [MESH:D014545] (521) Renal hypouricemia [MESH:C537757] (71) C13. Female Urogenital Diseases and Pregnancy Complications C13. Female Urogenital Diseases and Pregnancy Complications Female Urogenital Diseases [MESH:D052776] (8724) Urologic Diseases [MESH:D014570] (7793) Kidney Diseases [MESH:D007674] (7242) Renal Insufficiency [MESH:D051437] (4951) Acute Kidney Injury [MESH:D058186] (4142) Renal Tubular Transport, Inborn Errors [MESH:D015499] (1058) Renal hypouricemia [MESH:C537757] (71) Urolithiasis [MESH:D052878] (585) Urinary Calculi [MESH:D014545] (521) Renal hypouricemia [MESH:C537757] (71) C14. Cardiovascular Diseases C14. Cardiovascular Diseases Cardiovascular Diseases [MESH:D002318] (10123) Vascular Diseases [MESH:D014652] (8691) Venous Insufficiency [MESH:D014689] (11) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152) Genetic Diseases, Inborn [MESH:D030342] (9766) Metabolism, Inborn Errors [MESH:D008661] (6032) Renal Tubular Transport, Inborn Errors [MESH:D015499] (1027) Renal hypouricemia [MESH:C537757] (71) C18. Nutritional and Metabolic Diseases C18. Nutritional and Metabolic Diseases Metabolic Diseases [MESH:D008659] (9025) Brain Diseases, Metabolic [MESH:D001928] (3350) Hepatic Encephalopathy [MESH:D006501] (1795) Metabolism, Inborn Errors [MESH:D008661] (6028) Renal Tubular Transport, Inborn Errors [MESH:D015499] (1026) Renal hypouricemia [MESH:C537757] (71) C23. Pathological Conditions, Signs and Symptoms C23. Pathological Conditions, Signs and Symptoms Pathological Conditions, Anatomical [MESH:D020763] (6074) Calculi [MESH:D002137] (756) Urinary Calculi [MESH:D014545] (521) Renal hypouricemia [MESH:C537757] (71) Pathologic Processes [MESH:D010335] (9863) Hyperbilirubinemia [MESH:D006932] (1860) Jaundice [MESH:D007565] (316) Signs and Symptoms [MESH:D012816] (10659) Skin Manifestations [MESH:D012877] (1250) Jaundice [MESH:D007565] (316) C25. Chemically-Induced Disorders C25. Chemically-Induced Disorders Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839) Drug-Induced Liver Injury [MESH:D056486] (4936) Poisoning [MESH:D011041] (6703) Drug-Induced Liver Injury [MESH:D056486] (4936) D03. Heterocyclic Compounds D03. Heterocyclic Compounds Heterocyclic Compounds [MESH:D006571] (56330) Heterocyclic Compounds, 2-Ring [MESH:D006574] (24204) Benzofurans [MESH:D001572] (909) Benzbromarone [MESH:D001553] (7) D27. Chemical Actions and Uses D27. Chemical Actions and Uses Pharmacologic Actions [MESH:D020228] (2566) Molecular Mechanisms of Pharmacological Action [MESH:D045504] (1155) Fibrin Modulating Agents [MESH:D050299] (32) Fibrinolytic Agents [MESH:D005343] (30) Therapeutic Uses [MESH:D045506] (1611) Cardiovascular Agents [MESH:D002317] (271) Fibrinolytic Agents [MESH:D005343] (30) Hematologic Agents [MESH:D006401] (155) Fibrinolytic Agents [MESH:D005343] (30)
