Item 2 of 10 (back to results) previous next   protoporphyrinogen C011539               MeSH Unique Identifier: C011539 Chemical – Gene Interaction Note 1: CPOX protein results in increased chemical synthesis of protoporphyrinogen Note 2: Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen] Click here for more information

Current search: C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities: Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] × D04. Polycyclic Compounds: Polycyclic Compounds [MESH:D011083] > Macrocyclic Compounds [MESH:D047028] > Tetrapyrroles [MESH:D045725] > Porphyrins [MESH:D011166] > Protoporphyrins [MESH:D011524] × Select any link to see items in a related category. more general categories    information about this item 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Decreases (5154)   reaction (3393)  Increases (5571)   chemical synthesis (464)  reaction (1574) C01. Bacterial Infections and Mycoses  C01. Bacterial Infections and Mycoses  Infection [MESH:D007239] (4109)   Sepsis [MESH:D018805] (3556) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Neoplasms by Histologic Type [MESH:D009370] (8793)   Neoplasms, Complex and Mixed [MESH:D018193] (1121)   Carcinosarcoma [MESH:D002296] (581)  Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742)   Sarcoma [MESH:D012509] (4246)   Carcinosarcoma [MESH:D002296] (581)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Carcinoma [MESH:D002277] (7263)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Adenocarcinoma [MESH:D000230] (6565)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Carcinoma, Squamous Cell [MESH:D002294] (4294)  Papilloma [MESH:D010212] (2243)  Neoplasms by Site [MESH:D009371] (9169)   Skin Neoplasms [MESH:D012878] (2992)  Digestive System Neoplasms [MESH:D004067] (7487)   Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Metastasis [MESH:D009362] (4441)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Bone Diseases [MESH:D001847] (5801)   Bone Diseases, Developmental [MESH:D001848] (3315)   Acromicric dysplasia [MESH:C535662] (520)  Osteochondrodysplasias [MESH:D010009] (2440)   Camurati-Engelmann Syndrome [MESH:D003966] (492)  Bone Diseases, Metabolic [MESH:D001851] (3492)   Osteoporosis [MESH:D010024] (3037)   Osteoporosis, Postmenopausal [MESH:D015663] (2351)  Spinal Diseases [MESH:D013122] (2485)   Intervertebral Disc Degeneration [MESH:D055959] (827)  Muscular Diseases [MESH:D009135] (4071)   Muscular Disorders, Atrophic [MESH:D020966] (1598)   Muscular Dystrophies [MESH:D009136] (1593)   Muscular Dystrophy, Duchenne [MESH:D020388] (942)  Musculoskeletal Abnormalities [MESH:D009139] (3796)   Limb Deformities, Congenital [MESH:D017880] (1813)   Acromicric dysplasia [MESH:C535662] (520) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Gastrointestinal Diseases [MESH:D005767] (7443)   Intestinal Diseases [MESH:D007410] (6206)   Duodenal Diseases [MESH:D004378] (1982)   Peptic Ulcer [MESH:D010437] (1969)   Duodenal Ulcer [MESH:D004381] (1549)  Peptic Ulcer [MESH:D010437] (3172)   Duodenal Ulcer [MESH:D004381] (1549)  Liver Diseases [MESH:D008107] (8167)   Fatty Liver [MESH:D005234] (3584)   Non-alcoholic Fatty Liver Disease [MESH:C541083] (1567)  Hepatitis [MESH:D006505] (3883)   Hepatitis, Chronic [MESH:D006521] (2071)   Hepatitis, Autoimmune [MESH:D019693] (1982)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Alcoholic [MESH:D008104] (3066)  Liver Cirrhosis, Experimental [MESH:D008106] (4589)  Liver Diseases, Alcoholic [MESH:D008108] (3243)   Liver Cirrhosis, Alcoholic [MESH:D008104] (3066)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Pancreatic Diseases [MESH:D010182] (4453)   Cystic Fibrosis [MESH:D003550] (760)  Peritoneal Diseases [MESH:D010532] (1119)   Peritoneal Fibrosis [MESH:D056627] (488) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Mouth Diseases [MESH:D009059] (4783)   Oral Submucous Fibrosis [MESH:D009914] (2432) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Bronchial Diseases [MESH:D001982] (4382)   Asthma [MESH:D001249] (4098)  Lung Diseases [MESH:D008171] (7249)   Cystic Fibrosis [MESH:D003550] (760)  Lung Neoplasms [MESH:D008175] (6012)  Pneumonia [MESH:D011014] (3482)  Pulmonary Fibrosis [MESH:D011658] (3140)  Lung Diseases, Interstitial [MESH:D017563] (2966)   Pneumoconiosis [MESH:D011009] (2789)   Berylliosis [MESH:D001607] (2005)  Lung Diseases, Obstructive [MESH:D008173] (4697)   Asthma [MESH:D001249] (3903)  Pulmonary Disease, Chronic Obstructive [MESH:D029424] (3564)   Pulmonary Emphysema [MESH:D011656] (1259)  Lung Injury [MESH:D055370] (3688)   Acute Lung Injury [MESH:D055371] (1907)  Pneumoconiosis [MESH:D011009] (2789)   Berylliosis [MESH:D001607] (2005)  Respiratory Hypersensitivity [MESH:D012130] (4401)   Asthma [MESH:D001249] (4098)  Respiratory Tract Infections [MESH:D012141] (3926)   Pneumonia [MESH:D011014] (3482)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Cerebrovascular Disorders [MESH:D002561] (5542)   Stroke [MESH:D020521] (3702)  Neuromuscular Diseases [MESH:D009468] (7336)   Muscular Diseases [MESH:D009135] (3538)   Muscular Disorders, Atrophic [MESH:D020966] (1594)   Muscular Dystrophies [MESH:D009136] (1589)   Muscular Dystrophy, Duchenne [MESH:D020388] (942)  Peripheral Nervous System Diseases [MESH:D010523] (6151)   Diabetic Neuropathies [MESH:D003929] (2442) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Lacrimal Apparatus Diseases [MESH:D007766] (644)   Dry Eye Syndromes [MESH:D015352] (533) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Penile Diseases [MESH:D010409] (1805)   Penile Induration [MESH:D010411] (495)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Diabetic Nephropathies [MESH:D003928] (2301)  Uremia [MESH:D014511] (2898)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)   Glomerulonephritis, IGA [MESH:D005922] (897)  Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)  Nephrosis [MESH:D009401] (2228)   Nephrotic Syndrome [MESH:D009404] (1536)  Renal Insufficiency [MESH:D051437] (4951)   Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Ureteral Diseases [MESH:D014515] (1024)   Ureteral Obstruction [MESH:D014517] (575)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Diabetic Nephropathies [MESH:D003928] (2301)  Uremia [MESH:D014511] (2898)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)   Glomerulonephritis, IGA [MESH:D005922] (897)  Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)  Nephrosis [MESH:D009401] (2228)   Nephrotic Syndrome [MESH:D009404] (1536)  Renal Insufficiency [MESH:D051437] (4951)   Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Ureteral Diseases [MESH:D014515] (1024)   Ureteral Obstruction [MESH:D014517] (575)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293)  Pregnancy Complications [MESH:D011248] (4768)   Abortion, Spontaneous [MESH:D000022] (2780) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Heart Valve Diseases [MESH:D006349] (3333)   Aortic Valve Insufficiency [MESH:D001022] (1002)  Myocardial Ischemia [MESH:D017202] (5787)   Myocardial Infarction [MESH:D009203] (4122)  Vascular Diseases [MESH:D014652] (8691)   Hypertension [MESH:D006973] (5655)  Cerebrovascular Disorders [MESH:D002561] (5541)   Stroke [MESH:D020521] (3702)  Myocardial Ischemia [MESH:D017202] (5791)   Myocardial Infarction [MESH:D009203] (4151) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Blood Coagulation Disorders [MESH:D001778] (1828)   Thrombocythemia, Essential [MESH:D013920] (707)  Blood Platelet Disorders [MESH:D001791] (3174)   Thrombocytosis [MESH:D013922] (720)   Thrombocythemia, Essential [MESH:D013920] (707)  Bone Marrow Diseases [MESH:D001855] (2944)   Myeloproliferative Disorders [MESH:D009196] (1492)   Thrombocytosis [MESH:D013922] (720)   Thrombocythemia, Essential [MESH:D013920] (707)  Hemorrhagic Disorders [MESH:D006474] (3359)   Thrombocythemia, Essential [MESH:D013920] (707)  Lymphatic Diseases [MESH:D008206] (5167)   Lymphoproliferative Disorders [MESH:D008232] (4638)   Sarcoidosis [MESH:D012507] (895) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Musculoskeletal Abnormalities [MESH:D009139] (3779)   Limb Deformities, Congenital [MESH:D017880] (1813)   Acromicric dysplasia [MESH:C535662] (520)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Camurati-Engelmann Syndrome [MESH:D003966] (492)  Cystic Fibrosis [MESH:D003550] (760)  Genetic Diseases, X-Linked [MESH:D040181] (3028)   Muscular Dystrophy, Duchenne [MESH:D020388] (942)  Metabolism, Inborn Errors [MESH:D008661] (6032)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Muscular Dystrophies [MESH:D009136] (1597)   Muscular Dystrophy, Duchenne [MESH:D020388] (942)  Skin Diseases, Genetic [MESH:D012873] (3456)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Infant, Newborn, Diseases [MESH:D007232] (3064)   Cystic Fibrosis [MESH:D003550] (760) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Connective Tissue Diseases [MESH:D003240] (4490)   Penile Induration [MESH:D010411] (495)  Skin Diseases [MESH:D012871] (8774)   Skin Neoplasms [MESH:D012878] (2991)  Skin Diseases, Genetic [MESH:D012873] (3481)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Skin Diseases, Vascular [MESH:D017445] (3288)   Urticaria [MESH:D014581] (2668) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Glucose Metabolism Disorders [MESH:D044882] (6122)   Diabetes Mellitus [MESH:D003920] (5891)   Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Metabolism, Inborn Errors [MESH:D008661] (6028)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48)  Skin Diseases, Metabolic [MESH:D012875] (1574)   Porphyrias [MESH:D011164] (917)   Porphyrias, Hepatic [MESH:D017094] (881)   Coproporphyria, Hereditary [MESH:D046349] (38)  Porphyria Cutanea Tarda [MESH:D017119] (766)  Porphyria, Variegate [MESH:D046350] (50)   Porphyria, South African type [MESH:C538659] (48) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Diabetes Mellitus [MESH:D003920] (6159)   Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Diabetes Complications [MESH:D048909] (4129)   Diabetic Nephropathies [MESH:D003928] (2301)  Diabetic Neuropathies [MESH:D003929] (2443) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Autoimmune Diseases [MESH:D001327] (5067)   Glomerulonephritis, IGA [MESH:D005922] (897)  Hepatitis, Autoimmune [MESH:D019693] (1982)  Hypersensitivity [MESH:D006967] (5873)   Hypersensitivity, Immediate [MESH:D006969] (4980)   Urticaria [MESH:D014581] (2668)  Respiratory Hypersensitivity [MESH:D012130] (4250)   Asthma [MESH:D001249] (3914) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Ventricular Remodeling [MESH:D020257] (686)  Hernia [MESH:D006547] (2825)   Hernia, Diaphragmatic [MESH:D006548] (2647)  Pathologic Processes [MESH:D010335] (9863)   Hyperplasia [MESH:D006965] (2463)  Fibrosis [MESH:D005355] (3133)   Peritoneal Fibrosis [MESH:D056627] (488)  Inflammation [MESH:D007249] (5241)   Systemic Inflammatory Response Syndrome [MESH:D018746] (3563)   Sepsis [MESH:D018805] (3562)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Metastasis [MESH:D009362] (4441)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389)  Signs and Symptoms [MESH:D012816] (10659)   Urological Manifestations [MESH:D020924] (3532)   Proteinuria [MESH:D011507] (3293) C24. Occupational Diseases  C24. Occupational Diseases  Occupational Diseases [MESH:D009784] (3402)   Pneumoconiosis [MESH:D011009] (2670)   Berylliosis [MESH:D001607] (2005) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Substance-Related Disorders [MESH:D019966] (6308)   Alcohol-Related Disorders [MESH:D019973] (3869)   Alcohol-Induced Disorders [MESH:D020751] (3350)   Liver Diseases, Alcoholic [MESH:D008108] (3243)   Liver Cirrhosis, Alcoholic [MESH:D008104] (3066) D03. Heterocyclic Compounds  D03. Heterocyclic Compounds  Heterocyclic Compounds [MESH:D006571] (56330)   Heterocyclic Compounds, 1-Ring [MESH:D006573] (30631)   Azoles [MESH:D001393] (10398)   Pyrroles [MESH:D011758] (2361)   Tetrapyrroles [MESH:D045725] (1116)   Porphyrins [MESH:D011166] (952)   Protoporphyrins [MESH:D011524] (37)  Heterocyclic Compounds with 4 or More Rings [MESH:D006576] (2763)   Tetrapyrroles [MESH:D045725] (1116)   Porphyrins [MESH:D011166] (952)   Protoporphyrins [MESH:D011524] (37) D04. Polycyclic Compounds  D04. Polycyclic Compounds  Polycyclic Compounds [MESH:D011083] (22048)   Macrocyclic Compounds [MESH:D047028] (4784)   Tetrapyrroles [MESH:D045725] (1116)   Porphyrins [MESH:D011166] (952)   Protoporphyrins [MESH:D011524] (37) D23. Biological Factors  D23. Biological Factors  Biological Factors [MESH:D001685] (12003)   Pigments, Biological [MESH:D010860] (2018)   Porphyrins [MESH:D011166] (942)   Protoporphyrins [MESH:D011524] (37)