Item 184 of 454 (back to results) previous next   2,2',4,6,6'-pentachlorobiphenyl C417207               MeSH Unique Identifier: C417207 Chemical – Gene Interaction Note 1: SRC protein promotes the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of AKT1 protein] Note 2: 2,2',4,6,6'-pentachlorobiphenyl inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] Click here for more information

Current search: C05. Musculoskeletal Diseases: Musculoskeletal Diseases [MESH:D009140] × C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities: Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] > Genetic Diseases, Inborn [MESH:D030342] > Polycystic Kidney, Autosomal Recessive [MESH:D017044] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Ankyrin repeat domain containing [HGNC:ANKRD] (566)   nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 [HGNC:NFKB1] (254)  Basic leucine zipper proteins [HGNC:bZIP] (670)   FBJ murine osteosarcoma viral oncogene homolog [HGNC:FOS] (277)  jun proto-oncogene [HGNC:JUN] (290)  Cytochrome b [HGNC:CYB] (73)   cytochrome b-245, beta polypeptide [HGNC:CYBB] (27)  Endogenous Ligands [HGNC:ENDOLIG] (1191)   interleukin 08 [HGNC:IL8] (649)  Interleukins and interleukin receptors [HGNC:IL] (1294)   interleukin 08 [HGNC:IL8] (649)  Mitogen-activated protein kinase cascade [HGNC:MAP#K] (854)   Mitogen-activated protein kinases [HGNC:MAPK] (797)   mitogen-activated protein kinase 01 [HGNC:MAPK1] (651)  mitogen-activated protein kinase 03 [HGNC:MAPK3] (644)  mitogen-activated protein kinase 08 [HGNC:MAPK8] (234)  SH2 domain containing [HGNC:SH2D] (431)   v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [HGNC:SRC] (88)  Sulfotransferases, cytosolic [HGNC:SULT] (167)   sulfotransferase family 1E, estrogen-preferring, member 1 [HGNC:SULT1E1] (49) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   binding (2423)  Decreases (5154)   activity (2549)  expression (2187)  reaction (3393)  Increases (5571)   activity (2865)  cleavage (666)  expression (3238)  localization (244)  phosphorylation (1060)  reaction (1574) A. Anatomy  A. Anatomy  Cardiovascular System [MESH:D002319] (1086)   Heart [MESH:D006321] (904)   Heart Valves [MESH:D006351] (666)   Aortic Valve [MESH:D001021] (659)   Aortic Valve, Calcification of [MESH:C562942] (655) C01. Bacterial Infections and Mycoses  C01. Bacterial Infections and Mycoses  Bacterial Infections [MESH:D001424] (3716)   Gram-Negative Bacterial Infections [MESH:D016905] (3085)   Mycoplasmatales Infections [MESH:D009180] (1949)   Mycoplasma Infections [MESH:D009175] (1947)  Infection [MESH:D007239] (4109)   Sepsis [MESH:D018805] (3556) C03. Parasitic Diseases  C03. Parasitic Diseases  Parasitic Diseases [MESH:D010272] (3828)   Protozoan Infections [MESH:D011528] (3014)   Euglenozoa Infections [MESH:D056986] (2552)   Leishmaniasis [MESH:D007896] (2541)   Leishmaniasis, Cutaneous [MESH:D016773] (2359)  Skin Diseases, Parasitic [MESH:D012876] (2541)   Leishmaniasis [MESH:D007896] (2516)   Leishmaniasis, Cutaneous [MESH:D016773] (2359) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Precancerous Conditions [MESH:D011230] (2858)  Cysts [MESH:D003560] (2625)   Ovarian Cysts [MESH:D010048] (2534)  Neoplasms by Histologic Type [MESH:D009370] (8793)   Leukemia [MESH:D007938] (4576)   Leukemia, Myeloid [MESH:D007951] (2773)   Leukemia, Myelomonocytic, Juvenile [MESH:D054429] (344)  Leukemia, Myeloid, Acute [MESH:D015470] (2176)   Leukemia, Promyelocytic, Acute [MESH:D015473] (1367)  Lymphoma [MESH:D008223] (3686)   Hodgkin Disease [MESH:D006689] (1082)  Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742)   Neoplasms, Connective Tissue [MESH:D009372] (3626)   Neoplasms, Bone Tissue [MESH:D018213] (2217)   Osteosarcoma [MESH:D012516] (2175)  Sarcoma [MESH:D012509] (4246)   Hemangiosarcoma [MESH:D006394] (1836)  Osteosarcoma [MESH:D012516] (2175)  Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126)   Neuroectodermal Tumors [MESH:D017599] (5066)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Adenoma [MESH:D000236] (4051)   Mesothelioma [MESH:D008654] (2567)  Adenomatous Polyps [MESH:D018256] (1571)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Carcinoma [MESH:D002277] (7263)   Adenocarcinoma [MESH:D000230] (6565)   Adenocarcinoma of lung [MESH:C538231] (1487)  Carcinoma, Hepatocellular [MESH:D006528] (5375)  Cholangiocarcinoma [MESH:D018281] (2398)  Carcinoma in Situ [MESH:D002278] (2111)   Prostatic Intraepithelial Neoplasia [MESH:D019048] (1565)  Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms, Mesothelial [MESH:D018301] (2569)   Mesothelioma [MESH:D008654] (2567)  Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neoplasms, Squamous Cell [MESH:D018307] (4457)   Papilloma [MESH:D010212] (2243)  Carcinoma, Squamous Cell [MESH:D002294] (4294)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Neoplasms, Nerve Tissue [MESH:D009380] (5201)   Meningioma [MESH:D008579] (978)  Neuroectodermal Tumors [MESH:D017599] (5059)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Astrocytoma [MESH:D001254] (2692)   Glioblastoma [MESH:D005909] (2554)  Neoplasms, Vascular Tissue [MESH:D009383] (2959)   Hemangiosarcoma [MESH:D006394] (1836)  Meningioma [MESH:D008579] (978)  Neoplasms by Site [MESH:D009371] (9169)   Skin Neoplasms [MESH:D012878] (2992)  Breast Neoplasms [MESH:D001943] (6077)   Breast Neoplasms, Male [MESH:D018567] (650)  Digestive System Neoplasms [MESH:D004067] (7487)   Pancreatic Neoplasms [MESH:D010190] (3820)  Biliary Tract Neoplasms [MESH:D001661] (1165)   Bile Duct Neoplasms [MESH:D001650] (367)  Gastrointestinal Neoplasms [MESH:D005770] (6452)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5358)   Colorectal Neoplasms [MESH:D015179] (5294)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Rectal Neoplasms [MESH:D012004] (717)  Colonic Neoplasms [MESH:D003110] (4405)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Endocrine Gland Neoplasms [MESH:D004701] (4925)   Ovarian Neoplasms [MESH:D010051] (3275)  Pancreatic Neoplasms [MESH:D010190] (3820)  Head and Neck Neoplasms [MESH:D006258] (4612)   Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Otorhinolaryngologic Neoplasms [MESH:D010039] (1557)   Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Mammary Neoplasms, Animal [MESH:D015674] (3404)   Mammary Neoplasms, Experimental [MESH:D008325] (3268)  Nervous System Neoplasms [MESH:D009423] (3130)   Central Nervous System Neoplasms [MESH:D016543] (3055)   Meningeal Neoplasms [MESH:D008577] (984)   Meningioma [MESH:D008579] (978)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)   Adenocarcinoma of lung [MESH:C538231] (1487)  Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Small Cell Lung Carcinoma [MESH:D055752] (1380)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Female [MESH:D005833] (2540)   Uterine Neoplasms [MESH:D014594] (2431)   Endometrial Neoplasms [MESH:D016889] (1987)  Uterine Cervical Neoplasms [MESH:D002583] (978)  Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Neoplasms, Experimental [MESH:D009374] (5218)   Mammary Neoplasms, Experimental [MESH:D008325] (3268)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Neoplasm Recurrence, Local [MESH:D009364] (1949)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389)  Neoplastic Syndromes, Hereditary [MESH:D009386] (2578)   Adenomatous Polyposis Coli [MESH:D011125] (1565) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Bone Diseases [MESH:D001847] (5801)   Bone Diseases, Developmental [MESH:D001848] (3315)   Osteochondrodysplasias [MESH:D010009] (2440)   Fibrous Dysplasia of Bone [MESH:D005357] (737)  Joint Diseases [MESH:D007592] (4657)   Arthritis [MESH:D001168] (4416)   Arthritis, Rheumatoid [MESH:D001172] (3603)  Musculoskeletal Abnormalities [MESH:D009139] (3796)   Craniofacial Abnormalities [MESH:D019465] (3098)  Rheumatic Diseases [MESH:D012216] (4032)   Arthritis, Rheumatoid [MESH:D001172] (3603) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Biliary Tract Diseases [MESH:D001660] (3845)   Bile Duct Diseases [MESH:D001649] (3512)   Bile Duct Neoplasms [MESH:D001650] (367)  Cholestasis [MESH:D002779] (3419)   Cholestasis, Intrahepatic [MESH:D002780] (1510)   Liver Cirrhosis, Biliary [MESH:D008105] (1274)  Biliary Tract Neoplasms [MESH:D001661] (1165)   Bile Duct Neoplasms [MESH:D001650] (367)  Digestive System Abnormalities [MESH:D004065] (2127)   Barrett Esophagus [MESH:D001471] (1930)  Digestive System Neoplasms [MESH:D004067] (7493)   Pancreatic Neoplasms [MESH:D010190] (3820)  Biliary Tract Neoplasms [MESH:D001661] (1165)   Bile Duct Neoplasms [MESH:D001650] (367)  Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Rectal Neoplasms [MESH:D012004] (717)  Colonic Neoplasms [MESH:D003110] (4405)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Gastrointestinal Diseases [MESH:D005767] (7443)   Esophageal Diseases [MESH:D004935] (4255)   Barrett Esophagus [MESH:D001471] (1930)  Deglutition Disorders [MESH:D003680] (1538)   Esophageal Motility Disorders [MESH:D015154] (1489)   Gastroesophageal Reflux [MESH:D005764] (1465)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Esophagitis [MESH:D004941] (1120)   Esophagitis, Peptic [MESH:D004942] (709)  Gastroenteritis [MESH:D005759] (4066)   Colitis [MESH:D003092] (3199)   Colitis, Ulcerative [MESH:D003093] (2601)  Esophagitis [MESH:D004941] (1120)   Esophagitis, Peptic [MESH:D004942] (709)  Inflammatory Bowel Diseases [MESH:D015212] (3492)   Colitis, Ulcerative [MESH:D003093] (2601)  Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Esophageal Neoplasms [MESH:D004938] (3737)   Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Rectal Neoplasms [MESH:D012004] (717)  Colonic Neoplasms [MESH:D003110] (4405)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Intestinal Diseases [MESH:D007410] (6206)   Colonic Diseases [MESH:D003108] (5564)   Colitis [MESH:D003092] (3199)   Colitis, Ulcerative [MESH:D003093] (2601)  Colorectal Neoplasms [MESH:D015179] (5282)   Colonic Neoplasms [MESH:D003110] (4405)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Inflammatory Bowel Diseases [MESH:D015212] (3492)   Colitis, Ulcerative [MESH:D003093] (2601)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)   Rectal Neoplasms [MESH:D012004] (717)  Colonic Neoplasms [MESH:D003110] (4405)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Intestinal Polyposis [MESH:D044483] (1610)   Adenomatous Polyposis Coli [MESH:D011125] (1565)  Rectal Diseases [MESH:D012002] (4596)   Colorectal Neoplasms [MESH:D015179] (4534)   Rectal Neoplasms [MESH:D012004] (717)  Peptic Ulcer [MESH:D010437] (3172)   Esophagitis, Peptic [MESH:D004942] (709)  Stomach Diseases [MESH:D013272] (5325)   Stomach Neoplasms [MESH:D013274] (4942)  Liver Diseases [MESH:D008107] (8167)   Fatty Liver [MESH:D005234] (3584)  Hepatic Veno-Occlusive Disease [MESH:D006504] (208)  Cholestasis, Intrahepatic [MESH:D002780] (1510)   Liver Cirrhosis, Biliary [MESH:D008105] (1274)  Hepatic Insufficiency [MESH:D048550] (2771)   Liver Failure [MESH:D017093] (2768)   Liver Failure, Acute [MESH:D017114] (2404)  Liver Cirrhosis [MESH:D008103] (5542)   Liver Cirrhosis, Biliary [MESH:D008105] (1274)  Liver Cirrhosis, Experimental [MESH:D008106] (4589)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Pancreatic Diseases [MESH:D010182] (4453)   Pancreatic Neoplasms [MESH:D010190] (3820) C07. Stomatognathic Diseases  C07. Stomatognathic Diseases  Stomatognathic Diseases [MESH:D009057] (5348)   Mouth Diseases [MESH:D009059] (4783)   Behcet Syndrome [MESH:D001528] (1784)  Pharyngeal Diseases [MESH:D010608] (1562)   Nasopharyngeal Diseases [MESH:D009302] (1508)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Hypertension, Pulmonary [MESH:D006976] (2000)  Pneumonia [MESH:D011014] (3482)  Pulmonary Fibrosis [MESH:D011658] (3140)  Lung Diseases, Obstructive [MESH:D008173] (4697)   Pulmonary Disease, Chronic Obstructive [MESH:D029424] (3564)  Lung Neoplasms [MESH:D008175] (6012)   Adenocarcinoma of lung [MESH:C538231] (1487)  Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Small Cell Lung Carcinoma [MESH:D055752] (1380)  Respiratory Tract Infections [MESH:D012141] (3926)   Pneumonia [MESH:D011014] (3482)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013)   Adenocarcinoma of lung [MESH:C538231] (1487)  Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)  Small Cell Lung Carcinoma [MESH:D055752] (1380) C09. Otorhinolaryngologic Diseases  C09. Otorhinolaryngologic Diseases  Otorhinolaryngologic Diseases [MESH:D010038] (3827)   Otorhinolaryngologic Neoplasms [MESH:D010039] (1561)   Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Diseases [MESH:D010608] (1605)   Nasopharyngeal Diseases [MESH:D009302] (1508)   Nasopharyngeal Neoplasms [MESH:D009303] (1500)  Pharyngeal Neoplasms [MESH:D010610] (1520)   Nasopharyngeal Neoplasms [MESH:D009303] (1500) C10. Nervous System Diseases  C10. Nervous System Diseases  Z. Exceptions (4027)   Not Fully Specified [NFS] (4027)  Nervous System Diseases [MESH:D009422] (13325)   Neurotoxicity Syndromes [MESH:D020258] (4570)  Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Brain Injuries [MESH:D001930] (3429)  Cerebrovascular Disorders [MESH:D002561] (5542)   Brain Ischemia [MESH:D002545] (4873)   Brain Infarction [MESH:D020520] (2571)   Cerebral Infarction [MESH:D002544] (2458)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Intracranial Arterial Diseases [MESH:D020765] (2463)   Intracranial Aneurysm [MESH:D002532] (158)  Cerebral Arterial Diseases [MESH:D002539] (2440)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Intracranial Hemorrhages [MESH:D020300] (3269)   Cerebral Hemorrhage [MESH:D002543] (2873)  Stroke [MESH:D020521] (3702)   Brain Infarction [MESH:D020520] (2571)   Cerebral Infarction [MESH:D002544] (2458)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Dementia [MESH:D003704] (4498)   Alzheimer Disease [MESH:D000544] (4275)  Epilepsy [MESH:D004827] (6274)   Seizures [MESH:D012640] (4502)  Status Epilepticus [MESH:D013226] (4014)  Spinal Cord Diseases [MESH:D013118] (4376)   Spinal Cord Injuries [MESH:D013119] (1674)  Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Muscular Atrophy, Spinal [MESH:D009134] (850)   Bulbo-Spinal Atrophy, X-Linked [MESH:D055534] (566)   Bulbospinal neuronopathy, X-linked recessive [MESH:C537017] (565)  Nervous System Neoplasms [MESH:D009423] (3073)   Central Nervous System Neoplasms [MESH:D016543] (3055)   Meningeal Neoplasms [MESH:D008577] (984)   Meningioma [MESH:D008579] (978)  Neurodegenerative Diseases [MESH:D019636] (6613)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3243)   Bulbo-Spinal Atrophy, X-Linked [MESH:D055534] (566)   Bulbospinal neuronopathy, X-linked recessive [MESH:C537017] (565)  Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Muscular Atrophy, Spinal [MESH:D009134] (850)   Bulbo-Spinal Atrophy, X-Linked [MESH:D055534] (566)   Bulbospinal neuronopathy, X-linked recessive [MESH:C537017] (565)  Tauopathies [MESH:D024801] (4289)   Alzheimer Disease [MESH:D000544] (4275)  TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Neurologic Manifestations [MESH:D009461] (8964)   Seizures [MESH:D012640] (4514)  Dyskinesias [MESH:D020820] (3365)   Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (5230)   Memory Disorders [MESH:D008569] (3233)  Intellectual Disability [MESH:D008607] (3054)   Down Syndrome [MESH:D004314] (1287)  Neuromuscular Manifestations [MESH:D020879] (2130)   Muscular Atrophy [MESH:D009133] (1234)  Pain [MESH:D010146] (3875)   Pain, Intractable [MESH:D010148] (707)  Neuralgia [MESH:D009437] (2074)   Neuralgia, Postherpetic [MESH:D051474] (742)  Sensation Disorders [MESH:D012678] (5011)   Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Neuromuscular Diseases [MESH:D009468] (7336)   Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Muscular Atrophy, Spinal [MESH:D009134] (850)   Bulbo-Spinal Atrophy, X-Linked [MESH:D055534] (566)   Bulbospinal neuronopathy, X-linked recessive [MESH:C537017] (565)  Peripheral Nervous System Diseases [MESH:D010523] (6151)   Diabetic Neuropathies [MESH:D003929] (2442)  Neuralgia [MESH:D009437] (2078)   Neuralgia, Postherpetic [MESH:D051474] (742)  Trauma, Nervous System [MESH:D020196] (3997)   Spinal Cord Injuries [MESH:D013119] (1676)  Craniocerebral Trauma [MESH:D006259] (3507)   Brain Injuries [MESH:D001930] (3431) C11. Eye Diseases  C11. Eye Diseases  Eye Diseases [MESH:D005128] (6245)   Retinal Diseases [MESH:D012164] (3747)   Retinal Detachment [MESH:D012163] (1639)  Uveal Diseases [MESH:D014603] (2428)   Uveitis [MESH:D014605] (2157)   Panuveitis [MESH:D015864] (1805)   Uveitis, Anterior [MESH:D014606] (1791)   Behcet Syndrome [MESH:D001528] (1784) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Infertility [MESH:D007246] (2909)   Infertility, Male [MESH:D007248] (2851)  Penile Diseases [MESH:D010409] (1805)   Hypospadias [MESH:D007021] (798)   Hypospadias 1, X-Linked [MESH:C567482] (571)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Abnormalities [MESH:D014564] (2065)   Disorders of Sex Development [MESH:D012734] (1637)   46, XY Disorders of Sex Development [MESH:D058490] (1060)   Androgen-Insensitivity Syndrome [MESH:D013734] (567)  Hypospadias [MESH:D007021] (798)   Hypospadias 1, X-Linked [MESH:C567482] (571)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Hyperoxaluria [MESH:D006959] (1498)  Kidney Neoplasms [MESH:D007680] (3966)  Kidney Diseases, Cystic [MESH:D052177] (1009)   Polycystic Kidney Diseases [MESH:D007690] (853)   Polycystic Kidney, Autosomal Recessive [MESH:D017044] (462)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4374)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Endometriosis [MESH:D004715] (2461)  Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Ovarian Cysts [MESH:D010048] (2534)  Ovarian Neoplasms [MESH:D010051] (3281)  Infertility [MESH:D007246] (2211)   Infertility, Female [MESH:D007247] (2184)  Uterine Diseases [MESH:D014591] (2479)   Uterine Cervical Diseases [MESH:D002577] (988)   Uterine Cervical Neoplasms [MESH:D002583] (978)  Uterine Neoplasms [MESH:D014594] (2430)   Endometrial Neoplasms [MESH:D016889] (1984)  Uterine Cervical Neoplasms [MESH:D002583] (978)  Urogenital Abnormalities [MESH:D014564] (2043)   Disorders of Sex Development [MESH:D012734] (1637)   46, XY Disorders of Sex Development [MESH:D058490] (1060)   Androgen-Insensitivity Syndrome [MESH:D013734] (567)  Hypospadias [MESH:D007021] (798)   Hypospadias 1, X-Linked [MESH:C567482] (571)  Urogenital Neoplasms [MESH:D014565] (5792)   Genital Neoplasms, Female [MESH:D005833] (3810)   Ovarian Neoplasms [MESH:D010051] (3281)  Uterine Neoplasms [MESH:D014594] (2433)   Endometrial Neoplasms [MESH:D016889] (1989)  Uterine Cervical Neoplasms [MESH:D002583] (978)  Urologic Neoplasms [MESH:D014571] (5315)   Kidney Neoplasms [MESH:D007680] (3966)  Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Hyperoxaluria [MESH:D006959] (1498)  Kidney Neoplasms [MESH:D007680] (3966)  Kidney Diseases, Cystic [MESH:D052177] (1009)   Polycystic Kidney Diseases [MESH:D007690] (853)   Polycystic Kidney, Autosomal Recessive [MESH:D017044] (462)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Renal Insufficiency, Chronic [MESH:D051436] (2931)   Kidney Failure, Chronic [MESH:D007676] (2930)  Urinary Bladder Diseases [MESH:D001745] (4375)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Urination Disorders [MESH:D014555] (3598)   Proteinuria [MESH:D011507] (3293)  Pregnancy Complications [MESH:D011248] (4768)   Diabetes, Gestational [MESH:D016640] (1157) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Heart Failure [MESH:D006333] (4058)  Cardiomegaly [MESH:D006332] (4081)   Cardiomyopathy, Dilated [MESH:D002311] (1576)  Cardiomyopathies [MESH:D009202] (5331)   Cardiomyopathy, Dilated [MESH:D002311] (1576)  Myocardial Reperfusion Injury [MESH:D015428] (3500)  Heart Valve Diseases [MESH:D006349] (3333)   Aortic Valve Stenosis [MESH:D001024] (1742)   Aortic Valve, Calcification of [MESH:C562942] (655)  Myocardial Ischemia [MESH:D017202] (5787)   Myocardial Reperfusion Injury [MESH:D015428] (3500)  Angina Pectoris [MESH:D000787] (2575)   Angina, Unstable [MESH:D000789] (782)  Coronary Disease [MESH:D003327] (3439)   Coronary Artery Disease [MESH:D003324] (2685)  Coronary Stenosis [MESH:D023921] (1806)   Coronary Restenosis [MESH:D023903] (1683)  Ventricular Outflow Obstruction [MESH:D014694] (976)   Aortic Valve Stenosis [MESH:D001024] (810)   Aortic Valve, Calcification of [MESH:C562942] (655)  Vascular Diseases [MESH:D014652] (8691)   Hepatic Veno-Occlusive Disease [MESH:D006504] (208)  Hypertension [MESH:D006973] (5655)  Aneurysm [MESH:D000783] (1886)   Intracranial Aneurysm [MESH:D002532] (158)  Aortic Aneurysm [MESH:D001014] (1721)   Aortic Aneurysm, Abdominal [MESH:D017544] (1519)  Aortic Diseases [MESH:D001018] (1737)   Aortic Aneurysm [MESH:D001014] (1721)   Aortic Aneurysm, Abdominal [MESH:D017544] (1519)  Arterial Occlusive Diseases [MESH:D001157] (4520)   Arteriosclerosis [MESH:D001161] (4466)   Coronary Artery Disease [MESH:D003324] (2685)  Cerebrovascular Disorders [MESH:D002561] (5541)   Brain Ischemia [MESH:D002545] (4873)   Brain Infarction [MESH:D020520] (2571)   Cerebral Infarction [MESH:D002544] (2458)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Intracranial Arterial Diseases [MESH:D020765] (2468)   Intracranial Aneurysm [MESH:D002532] (158)  Cerebral Arterial Diseases [MESH:D002539] (2440)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Intracranial Hemorrhages [MESH:D020300] (3269)   Cerebral Hemorrhage [MESH:D002543] (2873)  Stroke [MESH:D020521] (3702)   Brain Infarction [MESH:D020520] (2571)   Cerebral Infarction [MESH:D002544] (2458)   Infarction, Middle Cerebral Artery [MESH:D020244] (2268)  Myocardial Ischemia [MESH:D017202] (5791)   Myocardial Reperfusion Injury [MESH:D015428] (3500)  Angina Pectoris [MESH:D000787] (2575)   Angina, Unstable [MESH:D000789] (782)  Coronary Disease [MESH:D003327] (3439)   Coronary Artery Disease [MESH:D003324] (2685)  Coronary Stenosis [MESH:D023921] (1806)   Coronary Restenosis [MESH:D023903] (1683)  Reperfusion Injury [MESH:D015427] (4968)   Myocardial Reperfusion Injury [MESH:D015428] (3500)  Vasculitis [MESH:D014657] (2604)   Behcet Syndrome [MESH:D001528] (1784) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Bone Marrow Diseases [MESH:D001855] (2944)   Myelodysplastic-Myeloproliferative Diseases [MESH:D054437] (376)   Leukemia, Myelomonocytic, Juvenile [MESH:D054429] (344)  Leukocyte Disorders [MESH:D007960] (2662)   Phagocyte Bactericidal Dysfunction [MESH:D010585] (998)   Granulomatous Disease, Chronic [MESH:D006105] (404)   Granulomatous Disease, Chronic, X-Linked [MESH:C564417] (111)  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I [MESH:C565532] (142)  Lymphatic Diseases [MESH:D008206] (5167)   Lymphoproliferative Disorders [MESH:D008232] (4638)   Lymphoma [MESH:D008223] (3684)   Hodgkin Disease [MESH:D006689] (1082) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Congenital Abnormalities [MESH:D000013] (8109)   Abnormalities, Multiple [MESH:D000015] (3192)   Down Syndrome [MESH:D004314] (1287)  Chromosome Disorders [MESH:D025063] (2030)   Down Syndrome [MESH:D004314] (1287)  Musculoskeletal Abnormalities [MESH:D009139] (3779)   Craniofacial Abnormalities [MESH:D019465] (3064)  Urogenital Abnormalities [MESH:D014564] (2064)   Disorders of Sex Development [MESH:D012734] (1637)   46, XY Disorders of Sex Development [MESH:D058490] (1060)   Androgen-Insensitivity Syndrome [MESH:D013734] (567)  Hypospadias [MESH:D007021] (798)   Hypospadias 1, X-Linked [MESH:C567482] (571)  Genetic Diseases, Inborn [MESH:D030342] (9766)   Polycystic Kidney, Autosomal Recessive [MESH:D017044] (462)  Chromosome Disorders [MESH:D025063] (2030)   Down Syndrome [MESH:D004314] (1287)  Genetic Diseases, X-Linked [MESH:D040181] (3028)   Hypospadias 1, X-Linked [MESH:C567482] (571)  Androgen-Insensitivity Syndrome [MESH:D013734] (567)  Bulbo-Spinal Atrophy, X-Linked [MESH:D055534] (566)   Bulbospinal neuronopathy, X-linked recessive [MESH:C537017] (565)  Granulomatous Disease, Chronic [MESH:D006105] (404)   Granulomatous Disease, Chronic, X-Linked [MESH:C564417] (111)  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I [MESH:C565532] (142)  Neoplastic Syndromes, Hereditary [MESH:D009386] (2578)   Adenomatous Polyposis Coli [MESH:D011125] (1565) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Connective Tissue Diseases [MESH:D003240] (4490)   Rheumatic Diseases [MESH:D012216] (3619)   Arthritis, Rheumatoid [MESH:D001172] (3603)  Skin Diseases [MESH:D012871] (8774)   Skin Neoplasms [MESH:D012878] (2991)  Acneiform Eruptions [MESH:D017486] (1312)   Chloracne [MESH:D054506] (1274)  Breast Diseases [MESH:D001941] (6148)   Breast Neoplasms [MESH:D001943] (6077)   Breast Neoplasms, Male [MESH:D018567] (650)  Facial Dermatoses [MESH:D005148] (1336)   Acneiform Eruptions [MESH:D017486] (1312)   Chloracne [MESH:D054506] (1274)  Hair Diseases [MESH:D006201] (1891)   Hypotrichosis [MESH:D007039] (1513)   Alopecia [MESH:D000505] (1453)  Skin Diseases, Infectious [MESH:D012874] (2684)   Skin Diseases, Parasitic [MESH:D012876] (2526)   Leishmaniasis [MESH:D007896] (2516)   Leishmaniasis, Cutaneous [MESH:D016773] (2359)  Skin Diseases, Papulosquamous [MESH:D017444] (3392)   Lichenoid Eruptions [MESH:D017512] (1324)  Psoriasis [MESH:D011565] (3278)  Skin Diseases, Vascular [MESH:D017445] (3288)   Behcet Syndrome [MESH:D001528] (1784)  Skin Diseases, Vesiculobullous [MESH:D012872] (1754)   Pemphigoid, Bullous [MESH:D010391] (707) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Calcium Metabolism Disorders [MESH:D002128] (3634)   Calcinosis [MESH:D002114] (2989)   Aortic Valve, Calcification of [MESH:C562942] (655)  Glucose Metabolism Disorders [MESH:D044882] (6122)   Diabetes Mellitus [MESH:D003920] (5891)   Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Diabetes, Gestational [MESH:D016640] (1152)  Hyperinsulinism [MESH:D006946] (3586)   Insulin Resistance [MESH:D007333] (3511)  Lipid Metabolism Disorders [MESH:D052439] (3225)   Dyslipidemias [MESH:D050171] (2428)   Hyperlipidemias [MESH:D006949] (1908)   Hypercholesterolemia [MESH:D006937] (1404)  Proteostasis Deficiencies [MESH:D057165] (3522)   TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Diabetes Mellitus [MESH:D003920] (6159)   Diabetes, Gestational [MESH:D016640] (1152)  Diabetes Mellitus, Experimental [MESH:D003921] (4771)  Diabetes Mellitus, Type 2 [MESH:D003924] (4219)  Diabetes Complications [MESH:D048909] (4129)   Diabetic Neuropathies [MESH:D003929] (2443)  Endocrine Gland Neoplasms [MESH:D004701] (4925)   Ovarian Neoplasms [MESH:D010051] (3275)  Pancreatic Neoplasms [MESH:D010190] (3820)  Gonadal Disorders [MESH:D006058] (5088)   Disorders of Sex Development [MESH:D012734] (1637)   46, XY Disorders of Sex Development [MESH:D058490] (1060)   Androgen-Insensitivity Syndrome [MESH:D013734] (567)  Ovarian Diseases [MESH:D010049] (4253)   Ovarian Cysts [MESH:D010048] (2534)  Ovarian Neoplasms [MESH:D010051] (3281) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Hypersensitivity [MESH:D006967] (5873)  Autoimmune Diseases [MESH:D001327] (5067)   Arthritis, Rheumatoid [MESH:D001172] (3601)  Pemphigoid, Bullous [MESH:D010391] (707)  Immunologic Deficiency Syndromes [MESH:D007153] (3788)   Phagocyte Bactericidal Dysfunction [MESH:D010585] (999)   Granulomatous Disease, Chronic [MESH:D006105] (404)   Granulomatous Disease, Chronic, X-Linked [MESH:C564417] (111)  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I [MESH:C565532] (142)  Immunoproliferative Disorders [MESH:D007160] (4761)   Lymphoproliferative Disorders [MESH:D008232] (4734)   Lymphoma [MESH:D008223] (3684)   Hodgkin Disease [MESH:D006689] (1082) C22. Animal Diseases  C22. Animal Diseases  Animal Diseases [MESH:D000820] (3656)   Mammary Neoplasms, Animal [MESH:D015674] (2735) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Alopecia [MESH:D000505] (1383)  Atrophy [MESH:D001284] (2603)   Muscular Atrophy [MESH:D009133] (1234)  Hypertrophy [MESH:D006984] (4476)   Cardiomegaly [MESH:D006332] (3802)  Splenomegaly [MESH:D013163] (1258)  Polyps [MESH:D011127] (1633)   Intestinal Polyps [MESH:D007417] (1592)  Pathologic Processes [MESH:D010335] (9863)   Gliosis [MESH:D005911] (1419)  Hyperplasia [MESH:D006965] (2463)  Nerve Degeneration [MESH:D009410] (4061)  Disease Attributes [MESH:D020969] (3654)   Disease Progression [MESH:D018450] (2868)  Hemorrhage [MESH:D006470] (4451)   Intracranial Hemorrhages [MESH:D020300] (3241)   Cerebral Hemorrhage [MESH:D002543] (2872)  Inflammation [MESH:D007249] (5241)   Systemic Inflammatory Response Syndrome [MESH:D018746] (3563)   Sepsis [MESH:D018805] (3562)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Neoplasm Recurrence, Local [MESH:D009364] (1949)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389)  Postoperative Complications [MESH:D011183] (5311)   Reperfusion Injury [MESH:D015427] (4968)   Myocardial Reperfusion Injury [MESH:D015428] (3500)  Signs and Symptoms [MESH:D012816] (10659)   Edema [MESH:D004487] (3726)  Body Temperature Changes [MESH:D001832] (3130)   Fever [MESH:D005334] (2856)  Body Weight [MESH:D001835] (4972)   Body Weight Changes [MESH:D001836] (3206)   Weight Loss [MESH:D015431] (2512)   Emaciation [MESH:D004614] (2285)   Cachexia [MESH:D002100] (2283)  Neurologic Manifestations [MESH:D009461] (8702)   Seizures [MESH:D012640] (4502)  Dyskinesias [MESH:D020820] (3285)   Hyperkinesis [MESH:D006948] (1799)  Neurobehavioral Manifestations [MESH:D019954] (4706)   Memory Disorders [MESH:D008569] (3233)  Neuromuscular Manifestations [MESH:D020879] (2130)   Muscular Atrophy [MESH:D009133] (1234)  Pain [MESH:D010146] (3869)   Pain, Intractable [MESH:D010148] (707)  Neuralgia [MESH:D009437] (2074)   Neuralgia, Postherpetic [MESH:D051474] (742)  Sensation Disorders [MESH:D012678] (5009)   Somatosensory Disorders [MESH:D020886] (4000)   Hyperalgesia [MESH:D006930] (3929)  Pain [MESH:D010146] (4511)   Pain, Intractable [MESH:D010148] (707)  Chest Pain [MESH:D002637] (2642)   Angina Pectoris [MESH:D000787] (2568)   Angina, Unstable [MESH:D000789] (782)  Neuralgia [MESH:D009437] (2074)   Neuralgia, Postherpetic [MESH:D051474] (742)  Urological Manifestations [MESH:D020924] (3532)   Proteinuria [MESH:D011507] (3293) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Poisoning [MESH:D011041] (6703)   Neurotoxicity Syndromes [MESH:D020258] (3323)  Psychoses, Substance-Induced [MESH:D011605] (2053)  Substance-Related Disorders [MESH:D019966] (6308)   Amphetamine-Related Disorders [MESH:D019969] (2858)  Cocaine-Related Disorders [MESH:D019970] (3054)  Marijuana Abuse [MESH:D002189] (1132)  Psychoses, Substance-Induced [MESH:D011605] (2052)  Substance Withdrawal Syndrome [MESH:D013375] (2956) C26. Wounds and Injuries  C26. Wounds and Injuries  Wounds and Injuries [MESH:D014947] (5171)   Spinal Cord Injuries [MESH:D013119] (2688)  Craniocerebral Trauma [MESH:D006259] (3523)   Brain Injuries [MESH:D001930] (3431)  Radiation Injuries [MESH:D011832] (2718)   Radiation Injuries, Experimental [MESH:D011833] (2662)  Trauma, Nervous System [MESH:D020196] (3535)   Craniocerebral Trauma [MESH:D006259] (3507)   Brain Injuries [MESH:D001930] (3431) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Hydrocarbons [MESH:D006838] (35762)   Hydrocarbons, Cyclic [MESH:D006844] (22983)   Hydrocarbons, Aromatic [MESH:D006841] (19108)   Benzene Derivatives [MESH:D001555] (10684)   Biphenyl Compounds [MESH:D001713] (678)   Polychlorinated Biphenyls [MESH:D011078] (104)  Hydrocarbons, Halogenated [MESH:D006846] (2296)   Hydrocarbons, Chlorinated [MESH:D006843] (491)   Polychlorinated Biphenyls [MESH:D011078] (112)