Item 28 of 158 (back to results) previous next   2-hydroxyestrone C024980               MeSH Unique Identifier: C024980 Scope Notes: Catechol estrogen which is a major metabolite of estradiol in man & animals Chemical – Gene Interaction Note 1: 2-hydroxyestrone binds to and results in increased activity of ESR1 protein Note 2: 2-hydroxyestrone binds to ESR1 protein Click here for more information

Current search: C18. Nutritional and Metabolic Diseases: Metabolic Diseases [MESH:D008659] > Lipid Metabolism Disorders [MESH:D052439] > Lipidoses [MESH:D008064] > Neuronal Ceroid-Lipofuscinoses [MESH:D009472] > Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] × C23. Pathological Conditions, Signs and Symptoms: Pathologic Processes [MESH:D010335] × Select any link to see items in a related category. more general categories    information about this item 1. Human Genes  1. Human Genes  Endogenous Ligands [HGNC:ENDOLIG] (1191)   follicle stimulating hormone, beta polypeptide [HGNC:FSHB] (68)  luteinizing hormone beta polypeptide [HGNC:LHB] (47)  Nuclear hormone receptors [HGNC:NR] (1322)   estrogen receptor 1 [HGNC:ESR1] (506)  estrogen receptor 2 (ER beta) [HGNC:ESR2] (261)  UDP glucuronosyltransferases [HGNC:UGT] (298)   UDP glucuronosyltransferase 1 family, polypeptide A1 [HGNC:UGT1A1] (167)  UDP glucuronosyltransferase 1 family, polypeptide A3 [HGNC:UGT1A3] (94)  UDP glucuronosyltransferase 1 family, polypeptide A9 [HGNC:UGT1A9] (108)  UDP glucuronosyltransferase 2 family, polypeptide B15 [HGNC:UGT2B15] (85) 2. Interaction: Human Genes and Chemicals  2. Interaction: Human Genes and Chemicals  Affects (3990)   binding (2423)  Decreases (5154)   expression (2187)  Increases (5571)   activity (2865)  glucuronidation (189)  metabolic processing (740) C04. Neoplasms  C04. Neoplasms  Neoplasms [MESH:D009369] (10293)   Cysts [MESH:D003560] (2625)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Neoplasms by Histologic Type [MESH:D009370] (8793)   Leukemia [MESH:D007938] (4576)  Lymphoma [MESH:D008223] (3686)   Hodgkin Disease [MESH:D006689] (1082)  Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742)   Neoplasms, Muscle Tissue [MESH:D009379] (1965)   Leiomyoma [MESH:D007889] (744)  Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126)   Neuroectodermal Tumors [MESH:D017599] (5066)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Medulloblastoma [MESH:D008527] (1282)  Neuroectodermal Tumors, Primitive [MESH:D018242] (2005)   Medulloblastoma [MESH:D008527] (1282)  Neoplasms, Glandular and Epithelial [MESH:D009375] (7760)   Adenoma [MESH:D000236] (4051)   Mesothelioma [MESH:D008654] (2567)  Carcinoma [MESH:D002277] (7263)   Carcinoma, Small Cell [MESH:D018288] (1317)  Carcinoma, Transitional Cell [MESH:D002295] (2662)  Adenocarcinoma [MESH:D000230] (6565)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Carcinoma, Renal Cell [MESH:D002292] (2975)  Carcinoma in Situ [MESH:D002278] (2111)   Prostatic Intraepithelial Neoplasia [MESH:D019048] (1565)  Neoplasms, Mesothelial [MESH:D018301] (2569)   Mesothelioma [MESH:D008654] (2567)  Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Medulloblastoma [MESH:D008527] (1282)  Neuroectodermal Tumors, Primitive [MESH:D018242] (2005)   Medulloblastoma [MESH:D008527] (1282)  Neoplasms, Nerve Tissue [MESH:D009380] (5201)   Neuroectodermal Tumors [MESH:D017599] (5059)   Neoplasms, Neuroepithelial [MESH:D018302] (4487)   Glioma [MESH:D005910] (4261)   Medulloblastoma [MESH:D008527] (1282)  Neuroectodermal Tumors, Primitive [MESH:D018242] (2005)   Medulloblastoma [MESH:D008527] (1282)  Neoplasms by Site [MESH:D009371] (9169)   Breast Neoplasms [MESH:D001943] (6077)  Digestive System Neoplasms [MESH:D004067] (7487)   Gastrointestinal Neoplasms [MESH:D005770] (6452)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5358)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Mammary Neoplasms, Animal [MESH:D015674] (3404)   Mammary Neoplasms, Experimental [MESH:D008325] (3268)  Thoracic Neoplasms [MESH:D013899] (6032)   Respiratory Tract Neoplasms [MESH:D012142] (6020)   Lung Neoplasms [MESH:D008175] (6015)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Small Cell Lung Carcinoma [MESH:D055752] (1380)  Urogenital Neoplasms [MESH:D014565] (7002)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Kidney Neoplasms [MESH:D007680] (3966)   Carcinoma, Renal Cell [MESH:D002292] (2975)  Neoplasms, Experimental [MESH:D009374] (5218)   Mammary Neoplasms, Experimental [MESH:D008325] (3268)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Neoplasm Recurrence, Local [MESH:D009364] (1949)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389) C05. Musculoskeletal Diseases  C05. Musculoskeletal Diseases  Musculoskeletal Diseases [MESH:D009140] (8705)   Bone Diseases [MESH:D001847] (5801)   Bone Diseases, Metabolic [MESH:D001851] (3492)  Joint Diseases [MESH:D007592] (4657)   Arthritis [MESH:D001168] (4416)   Arthritis, Rheumatoid [MESH:D001172] (3603)  Osteoarthritis [MESH:D010003] (1743)  Rheumatic Diseases [MESH:D012216] (4032)   Arthritis, Rheumatoid [MESH:D001172] (3603)  Osteoarthritis [MESH:D010003] (1743) C06. Digestive System Diseases  C06. Digestive System Diseases  Digestive System Diseases [MESH:D004066] (9461)   Digestive System Neoplasms [MESH:D004067] (7493)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375)  Gastrointestinal Diseases [MESH:D005767] (7443)   Gastrointestinal Neoplasms [MESH:D005770] (6460)   Stomach Neoplasms [MESH:D013274] (4942)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Intestinal Diseases [MESH:D007410] (6206)   Colonic Diseases [MESH:D003108] (5564)   Colorectal Neoplasms [MESH:D015179] (5282)  Intestinal Neoplasms [MESH:D007414] (5359)   Colorectal Neoplasms [MESH:D015179] (5294)  Rectal Diseases [MESH:D012002] (4596)   Colorectal Neoplasms [MESH:D015179] (4534)  Stomach Diseases [MESH:D013272] (5325)   Stomach Neoplasms [MESH:D013274] (4942)  Liver Diseases [MESH:D008107] (8167)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Liver Neoplasms [MESH:D008113] (6048)   Carcinoma, Hepatocellular [MESH:D006528] (5375) C08. Respiratory Tract Diseases  C08. Respiratory Tract Diseases  Respiratory Tract Diseases [MESH:D012140] (7881)   Lung Diseases [MESH:D008171] (7249)   Lung Neoplasms [MESH:D008175] (6012)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Small Cell Lung Carcinoma [MESH:D055752] (1380)  Respiratory Tract Neoplasms [MESH:D012142] (6053)   Lung Neoplasms [MESH:D008175] (6013)   Bronchial Neoplasms [MESH:D001984] (3608)   Carcinoma, Bronchogenic [MESH:D002283] (3606)   Small Cell Lung Carcinoma [MESH:D055752] (1380) C10. Nervous System Diseases  C10. Nervous System Diseases  Nervous System Diseases [MESH:D009422] (13325)   Central Nervous System Diseases [MESH:D002493] (9745)   Brain Diseases [MESH:D001927] (9294)   Brain Diseases, Metabolic [MESH:D001928] (3351)   Kernicterus [MESH:D007647] (256)  Cerebrovascular Disorders [MESH:D002561] (5542)   Brain Ischemia [MESH:D002545] (4873)   Brain Infarction [MESH:D020520] (2571)   Brain Stem Infarctions [MESH:D020526] (198)   Lateral Medullary Syndrome [MESH:D014854] (188)  Stroke [MESH:D020521] (3702)   Brain Infarction [MESH:D020520] (2571)   Brain Stem Infarctions [MESH:D020526] (198)   Lateral Medullary Syndrome [MESH:D014854] (188)  Dementia [MESH:D003704] (4498)   Alzheimer Disease [MESH:D000544] (4275)  Headache Disorders [MESH:D020773] (2337)   Headache Disorders, Primary [MESH:D051270] (2327)   Migraine Disorders [MESH:D008881] (2318)  Hypothalamic Diseases [MESH:D007027] (1833)   Pituitary Diseases [MESH:D010900] (1808)   Hyperpituitarism [MESH:D006964] (1250)   Hyperprolactinemia [MESH:D006966] (603)  Spinal Cord Diseases [MESH:D013118] (4376)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Neurodegenerative Diseases [MESH:D019636] (6613)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3243)   Neuronal Ceroid-Lipofuscinoses [MESH:D009472] (1026)   Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] (159)  Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Tauopathies [MESH:D024801] (4289)   Alzheimer Disease [MESH:D000544] (4275)  TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Neuromuscular Diseases [MESH:D009468] (7336)   Peripheral Nervous System Diseases [MESH:D010523] (6151)  Motor Neuron Disease [MESH:D016472] (3670)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559) C12. Male Urogenital Diseases  C12. Male Urogenital Diseases  Male Urogenital Diseases [MESH:D052801] (8891)   Genital Diseases, Male [MESH:D005832] (6794)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Infertility [MESH:D007246] (2909)   Infertility, Male [MESH:D007248] (2851)   Oligospermia [MESH:D009845] (799)   Follicle-stimulating hormone deficiency, isolated [MESH:C537070] (185)  Prostatic Diseases [MESH:D011469] (6204)   Prostatic Neoplasms [MESH:D011471] (6135)  Urogenital Neoplasms [MESH:D014565] (6932)   Genital Neoplasms, Male [MESH:D005834] (6224)   Prostatic Neoplasms [MESH:D011471] (6135)  Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Kidney Neoplasms [MESH:D007680] (3966)   Carcinoma, Renal Cell [MESH:D002292] (2975)  Urologic Diseases [MESH:D014570] (7792)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)   Carcinoma, Renal Cell [MESH:D002292] (2975)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urinary Bladder Diseases [MESH:D001745] (4374)   Urinary Bladder Neoplasms [MESH:D001749] (4079) C13. Female Urogenital Diseases and Pregnancy Complications  C13. Female Urogenital Diseases and Pregnancy Complications  Z. Exceptions (1116)   Not Fully Specified [NFS] (1116)  Female Urogenital Diseases [MESH:D052776] (8724)   Genital Diseases, Female [MESH:D005831] (5563)   Endometriosis [MESH:D004715] (2461)  Adnexal Diseases [MESH:D000291] (4273)   Ovarian Diseases [MESH:D010049] (4255)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Infertility [MESH:D007246] (2211)   Infertility, Female [MESH:D007247] (2184)  Urogenital Neoplasms [MESH:D014565] (5792)   Urologic Neoplasms [MESH:D014571] (5315)   Urinary Bladder Neoplasms [MESH:D001749] (4079)  Kidney Neoplasms [MESH:D007680] (3966)   Carcinoma, Renal Cell [MESH:D002292] (2975)  Urologic Diseases [MESH:D014570] (7793)   Kidney Diseases [MESH:D007674] (7242)   Kidney Neoplasms [MESH:D007680] (3966)   Carcinoma, Renal Cell [MESH:D002292] (2975)  Nephritis [MESH:D009393] (4236)   Glomerulonephritis [MESH:D005921] (3758)  Renal Insufficiency [MESH:D051437] (4951)   Acute Kidney Injury [MESH:D058186] (4142)  Urinary Bladder Diseases [MESH:D001745] (4375)   Urinary Bladder Neoplasms [MESH:D001749] (4079) C14. Cardiovascular Diseases  C14. Cardiovascular Diseases  Cardiovascular Diseases [MESH:D002318] (10123)   Heart Diseases [MESH:D006331] (8614)   Arrhythmias, Cardiac [MESH:D001145] (4679)   Bradycardia [MESH:D001919] (1899)  Tachycardia [MESH:D013610] (3339)  Cardiomegaly [MESH:D006332] (4081)   Hypertrophy, Left Ventricular [MESH:D017379] (1430)  Myocardial Ischemia [MESH:D017202] (5787)   Acute Coronary Syndrome [MESH:D054058] (2286)  Myocardial Infarction [MESH:D009203] (4122)  Angina Pectoris [MESH:D000787] (2575)   Acute Coronary Syndrome [MESH:D054058] (2286)  Coronary Disease [MESH:D003327] (3439)   Coronary Artery Disease [MESH:D003324] (2685)  Vascular Diseases [MESH:D014652] (8691)   Hypertension [MESH:D006973] (5655)  Arterial Occlusive Diseases [MESH:D001157] (4520)   Arteriosclerosis [MESH:D001161] (4466)   Atherosclerosis [MESH:D050197] (4188)  Coronary Artery Disease [MESH:D003324] (2685)  Cerebrovascular Disorders [MESH:D002561] (5541)   Brain Ischemia [MESH:D002545] (4873)   Brain Infarction [MESH:D020520] (2571)   Brain Stem Infarctions [MESH:D020526] (198)   Lateral Medullary Syndrome [MESH:D014854] (188)  Stroke [MESH:D020521] (3702)   Brain Infarction [MESH:D020520] (2571)   Brain Stem Infarctions [MESH:D020526] (198)   Lateral Medullary Syndrome [MESH:D014854] (188)  Myocardial Ischemia [MESH:D017202] (5791)   Acute Coronary Syndrome [MESH:D054058] (2286)  Myocardial Infarction [MESH:D009203] (4151)  Angina Pectoris [MESH:D000787] (2575)   Acute Coronary Syndrome [MESH:D054058] (2286)  Coronary Disease [MESH:D003327] (3439)   Coronary Artery Disease [MESH:D003324] (2685) C15. Hemic and Lymphatic Diseases  C15. Hemic and Lymphatic Diseases  Hematologic Diseases [MESH:D006402] (6174)   Blood Group Incompatibility [MESH:D001787] (277)   Erythroblastosis, Fetal [MESH:D004899] (275)   Kernicterus [MESH:D007647] (256)  Leukocyte Disorders [MESH:D007960] (2662)   Leukopenia [MESH:D007970] (1921)   Agranulocytosis [MESH:D000380] (1675)   Neutropenia [MESH:D009503] (1629)  Lymphatic Diseases [MESH:D008206] (5167)   Lymphoproliferative Disorders [MESH:D008232] (4638)   Lymphoma [MESH:D008223] (3684)   Hodgkin Disease [MESH:D006689] (1082) C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities  Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152)   Genetic Diseases, Inborn [MESH:D030342] (9766)   Heredodegenerative Disorders, Nervous System [MESH:D020271] (3465)   Neuronal Ceroid-Lipofuscinoses [MESH:D009472] (1026)   Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] (159)  Metabolism, Inborn Errors [MESH:D008661] (6032)   Hyperbilirubinemia, Hereditary [MESH:D006933] (476)   Hyperbilirubinemia, Transient Familial Neonatal [MESH:C562692] (254)  Gilbert Disease [MESH:D005878] (259)  Crigler-Najjar Syndrome [MESH:D003414] (255)   Crigler Najjar syndrome, type 2 [MESH:C536213] (254)  Lipid Metabolism, Inborn Errors [MESH:D008052] (2071)   Lipidoses [MESH:D008064] (1655)   Neuronal Ceroid-Lipofuscinoses [MESH:D009472] (1026)   Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] (159)  Infant, Newborn, Diseases [MESH:D007232] (3064)   Erythroblastosis, Fetal [MESH:D004899] (257)   Kernicterus [MESH:D007647] (256)  Hyperbilirubinemia, Neonatal [MESH:D051556] (469)   Hyperbilirubinemia, Transient Familial Neonatal [MESH:C562692] (254) C17. Skin and Connective Tissue Diseases  C17. Skin and Connective Tissue Diseases  Connective Tissue Diseases [MESH:D003240] (4490)   Rheumatic Diseases [MESH:D012216] (3619)   Arthritis, Rheumatoid [MESH:D001172] (3603)  Skin Diseases [MESH:D012871] (8774)   Breast Diseases [MESH:D001941] (6148)   Breast Neoplasms [MESH:D001943] (6077) C18. Nutritional and Metabolic Diseases  C18. Nutritional and Metabolic Diseases  Metabolic Diseases [MESH:D008659] (9025)   Brain Diseases, Metabolic [MESH:D001928] (3350)   Kernicterus [MESH:D007647] (256)  Lipid Metabolism Disorders [MESH:D052439] (3225)   Lipidoses [MESH:D008064] (1655)   Neuronal Ceroid-Lipofuscinoses [MESH:D009472] (1026)   Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] (159)  Metabolism, Inborn Errors [MESH:D008661] (6028)   Hyperbilirubinemia, Hereditary [MESH:D006933] (476)   Hyperbilirubinemia, Transient Familial Neonatal [MESH:C562692] (254)  Gilbert Disease [MESH:D005878] (259)  Crigler-Najjar Syndrome [MESH:D003414] (255)   Crigler Najjar syndrome, type 2 [MESH:C536213] (254)  Lipid Metabolism, Inborn Errors [MESH:D008052] (2071)   Lipidoses [MESH:D008064] (1655)   Neuronal Ceroid-Lipofuscinoses [MESH:D009472] (1026)   Ceroid Lipofuscinosis, Neuronal, 10 [MESH:C566438] (159)  Proteostasis Deficiencies [MESH:D057165] (3522)   TDP-43 Proteinopathies [MESH:D057177] (3337)   Amyotrophic Lateral Sclerosis [MESH:D000690] (3296)   Amyotrophic lateral sclerosis 1 [MESH:C531617] (2559)  Nutrition Disorders [MESH:D009748] (4945)   Overnutrition [MESH:D044343] (4463)   Obesity [MESH:D009765] (4462) C19. Endocrine System Diseases  C19. Endocrine System Diseases  Endocrine System Diseases [MESH:D004700] (8062)   Gonadal Disorders [MESH:D006058] (5088)   Hypogonadism [MESH:D007006] (1123)  Puberty, Delayed [MESH:D011628] (449)  Ovarian Diseases [MESH:D010049] (4253)   Ovarian Cysts [MESH:D010048] (2534)   Polycystic Ovary Syndrome [MESH:D011085] (2186)  Pituitary Diseases [MESH:D010900] (1829)   Hyperpituitarism [MESH:D006964] (1259)   Hyperprolactinemia [MESH:D006966] (603) C20. Immune System Diseases  C20. Immune System Diseases  Immune System Diseases [MESH:D007154] (7674)   Autoimmune Diseases [MESH:D001327] (5067)   Arthritis, Rheumatoid [MESH:D001172] (3601)  Blood Group Incompatibility [MESH:D001787] (277)   Erythroblastosis, Fetal [MESH:D004899] (275)   Kernicterus [MESH:D007647] (256)  Immunoproliferative Disorders [MESH:D007160] (4761)   Lymphoproliferative Disorders [MESH:D008232] (4734)   Lymphoma [MESH:D008223] (3684)   Hodgkin Disease [MESH:D006689] (1082) C22. Animal Diseases  C22. Animal Diseases  Animal Diseases [MESH:D000820] (3656)   Disease Models, Animal [MESH:D004195] (2058)  Mammary Neoplasms, Animal [MESH:D015674] (2735) C23. Pathological Conditions, Signs and Symptoms  C23. Pathological Conditions, Signs and Symptoms  Pathological Conditions, Anatomical [MESH:D020763] (6074)   Hypertrophy [MESH:D006984] (4476)   Cardiomegaly [MESH:D006332] (3802)   Hypertrophy, Left Ventricular [MESH:D017379] (1430)  Pathologic Processes [MESH:D010335] (9863)   Lithiasis [MESH:D020347] (345)  Arrhythmias, Cardiac [MESH:D001145] (4658)   Bradycardia [MESH:D001919] (1899)  Tachycardia [MESH:D013610] (3339)  Chromosome Aberrations [MESH:D002869] (2352)   Aneuploidy [MESH:D000782] (1237)  Chromosome Breakage [MESH:D019457] (139)  Disease Attributes [MESH:D020969] (3654)   Disease Progression [MESH:D018450] (2868)  Hyperbilirubinemia [MESH:D006932] (1860)   Kernicterus [MESH:D007647] (256)  Hyperbilirubinemia, Neonatal [MESH:D051556] (258)   Hyperbilirubinemia, Transient Familial Neonatal [MESH:C562692] (254)  Menstruation Disturbances [MESH:D008599] (926)   Amenorrhea [MESH:D000568] (817)  Neoplastic Processes [MESH:D009385] (5317)   Neoplasm Invasiveness [MESH:D009361] (3388)  Neoplasm Metastasis [MESH:D009362] (4441)  Neoplasm Recurrence, Local [MESH:D009364] (1949)  Carcinogenesis [MESH:D063646] (3391)   Cell Transformation, Neoplastic [MESH:D002471] (3389)  Signs and Symptoms [MESH:D012816] (10659)   Feminization [MESH:D005262] (655)  Body Temperature Changes [MESH:D001832] (3130)   Fever [MESH:D005334] (2856)  Hypothermia [MESH:D007035] (2075)  Body Weight [MESH:D001835] (4972)   Body Weight Changes [MESH:D001836] (3206)   Weight Gain [MESH:D015430] (2595)  Overweight [MESH:D050177] (4455)   Obesity [MESH:D009765] (4454)  Pain [MESH:D010146] (4511)   Chest Pain [MESH:D002637] (2642)   Angina Pectoris [MESH:D000787] (2568)   Acute Coronary Syndrome [MESH:D054058] (2286) C25. Chemically-Induced Disorders  C25. Chemically-Induced Disorders  Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Poisoning [MESH:D011041] (6703)   Drug-Induced Liver Injury [MESH:D056486] (4936)  Psychoses, Substance-Induced [MESH:D011605] (2053)  Substance-Related Disorders [MESH:D019966] (6308)   Cocaine-Related Disorders [MESH:D019970] (3054)  Psychoses, Substance-Induced [MESH:D011605] (2052)  Alcohol-Related Disorders [MESH:D019973] (3869)   Alcoholism [MESH:D000437] (1519) D02. Organic Chemicals  D02. Organic Chemicals  Organic Chemicals [MESH:D009930] (75987)   Hydrocarbons [MESH:D006838] (35762)   Hydrocarbons, Cyclic [MESH:D006844] (22983)   Hydrocarbons, Aromatic [MESH:D006841] (19108)   Benzene Derivatives [MESH:D001555] (10684)   Phenols [MESH:D010636] (3676)   Catechols [MESH:D002396] (417)   Estrogens, Catechol [MESH:D002393] (31)   Hydroxyestrones [MESH:D006894] (27) D04. Polycyclic Compounds  D04. Polycyclic Compounds  Polycyclic Compounds [MESH:D011083] (22048)   Steroids [MESH:D013256] (6272)   Estranes [MESH:D004962] (685)   Estrenes [MESH:D004963] (672)   Estrone [MESH:D004970] (120)   Hydroxyestrones [MESH:D006894] (27)  Ketosteroids [MESH:D007664] (300)   17-Ketosteroids [MESH:D015068] (294)   Estrone [MESH:D004970] (120)   Hydroxyestrones [MESH:D006894] (27) D06. Hormones, Hormone Substitutes, and Hormone Antagonists  D06. Hormones, Hormone Substitutes, and Hormone Antagonists  Hormones [MESH:D006728] (4254)   Gonadal Hormones [MESH:D042341] (1226)   Gonadal Steroid Hormones [MESH:D012739] (1172)   Estradiol Congeners [MESH:D045166] (585)   Estrogens, Catechol [MESH:D002393] (31)   Hydroxyestrones [MESH:D006894] (27) D27. Chemical Actions and Uses  D27. Chemical Actions and Uses  Pharmacologic Actions [MESH:D020228] (2566)   Physiological Effects of Drugs [MESH:D045505] (1186)   Protective Agents [MESH:D020011] (164)   Anticarcinogenic Agents [MESH:D016588] (20)  Therapeutic Uses [MESH:D045506] (1611)   Antineoplastic Agents [MESH:D000970] (319)   Anticarcinogenic Agents [MESH:D016588] (20)  Specialty Uses of Chemicals [MESH:D020313] (713)   Protective Agents [MESH:D020011] (151)   Anticarcinogenic Agents [MESH:D016588] (20)