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 lupeol
C010480
 
  
  
  

MeSH Unique Identifier: C010480
Chemical – Gene Interaction

Note 1: Lupeol results in decreased localization of and results in decreased activity of CTNNB1 protein

Note 2: Lupeol results in increased expression of PTEN protein

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C04. Neoplasms: Neoplasms [MESH:D009369] > Pregnancy Complications, Neoplastic [MESH:D011252]
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1. Human Genes 
1. Human Genes
 Armadillo repeat containing [HGNC:ARMC] (176) 
 catenin (cadherin-associated protein), beta 1, 88kDa [HGNC:CTNNB1] (129)
 Protein tyrosine phosphatases, including dual specificity phosphatases [HGNC:PTP] (254) 
 Protein tyrosine phosphatases, Class I Cys-based [HGNC:PTPN] (252) 
 Class I Cys-based PTPs : PTENs [HGNC:DUSPQ] (91) 
 phosphatase and tensin homolog [HGNC:PTEN] (91)
2. Interaction: Human Genes and Chemicals 
2. Interaction: Human Genes and Chemicals
 Decreases (5154) 
 activity (2549)
 localization (74)
 Increases (5571) 
 expression (3238)
 response to substance (641)
A. Anatomy 
A. Anatomy
 Musculoskeletal System [MESH:D009141] (1255) 
 Skeleton [MESH:D012863] (1177) 
 Bone and Bones [MESH:D001842] (1112) 
 Spine [MESH:D013131] (258) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Digestive System [MESH:D004064] (421) 
 Gastrointestinal Tract [MESH:D041981] (364) 
 Intestines [MESH:D007422] (271) 
 Intestine, Large [MESH:D007420] (247) 
 Anal Canal [MESH:D001003] (217) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Lower Gastrointestinal Tract [MESH:D041741] (254) 
 Intestine, Large [MESH:D007420] (247) 
 Anal Canal [MESH:D001003] (217) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Upper Gastrointestinal Tract [MESH:D041742] (236) 
 Esophagus [MESH:D004947] (200) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Respiratory System [MESH:D012137] (321) 
 Trachea [MESH:D014132] (190) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Urogenital System [MESH:D014566] (986) 
 Urinary Tract [MESH:D014551] (721) 
 Kidney [MESH:D007668] (707) 
 VACTERL hydrocephaly [MESH:C536521] (151)
C01. Bacterial Infections and Mycoses 
C01. Bacterial Infections and Mycoses
 Infection [MESH:D007239] (4109) 
 Intraabdominal Infections [MESH:D059413] (958) 
 Peritonitis [MESH:D010538] (800)
C02. Virus Diseases 
C02. Virus Diseases
 Virus Diseases [MESH:D014777] (4544) 
 DNA Virus Infections [MESH:D004266] (2474) 
 Herpesviridae Infections [MESH:D006566] (1944) 
 Epstein-Barr Virus Infections [MESH:D020031] (695) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Tumor Virus Infections [MESH:D014412] (1069) 
 Epstein-Barr Virus Infections [MESH:D020031] (693) 
 Burkitt Lymphoma [MESH:D002051] (691)
C04. Neoplasms 
C04. Neoplasms
 Neoplasms [MESH:D009369] (10293) 
 Hamartoma [MESH:D006222] (1484) 
 Hamartoma Syndrome, Multiple [MESH:D006223] (262) 
 Proteus Syndrome [MESH:D016715] (152)
 Neoplasms by Histologic Type [MESH:D009370] (8793) 
 Leukemia [MESH:D007938] (4576) 
 Leukemia, Lymphoid [MESH:D007945] (3047) 
 Leukemia, B-Cell [MESH:D015448] (2564) 
 Leukemia, Lymphocytic, Chronic, B-Cell [MESH:D015451] (2562)
 Precursor Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054198] (1754) 
 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054218] (510)
 Lymphoma [MESH:D008223] (3686) 
 Lymphoma, Non-Hodgkin [MESH:D008228] (3337) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Mantle-Cell [MESH:D020522] (561)
 Lymphoma, B-Cell [MESH:D016393] (2624) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Large B-Cell, Diffuse [MESH:D016403] (2012)
 Neoplasms, Complex and Mixed [MESH:D018193] (1121) 
 Hepatoblastoma [MESH:D018197] (548)
 Mixed Tumor, Mullerian [MESH:D018200] (64)
 Wilms Tumor [MESH:D009396] (553)
 Neoplasms, Connective and Soft Tissue [MESH:D018204] (4742) 
 Neoplasms, Adipose Tissue [MESH:D018205] (677) 
 Lipoma [MESH:D008067] (159)
 Neoplasms, Connective Tissue [MESH:D009372] (3626) 
 Chondrosarcoma [MESH:D002813] (1217) 
 Chondrosarcoma, Mesenchymal [MESH:D018211] (1161)
 Sarcoma [MESH:D012509] (4246) 
 Hemangiosarcoma [MESH:D006394] (1836)
 Chondrosarcoma [MESH:D002813] (1217) 
 Chondrosarcoma, Mesenchymal [MESH:D018211] (1161)
 Neoplasms, Germ Cell and Embryonal [MESH:D009373] (5126) 
 Neuroectodermal Tumors [MESH:D017599] (5066) 
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Astrocytoma [MESH:D001254] (2692) 
 Glioblastoma [MESH:D005909] (2554)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive, Peripheral [MESH:D018241] (1433) 
 Neuroblastoma [MESH:D009447] (1420)
 Neuroendocrine Tumors [MESH:D018358] (3633) 
 Melanoma [MESH:D008545] (3508)
 Trophoblastic Neoplasms [MESH:D014328] (68) 
 Gestational Trophoblastic Disease [MESH:D031901] (65)
 Neoplasms, Glandular and Epithelial [MESH:D009375] (7760) 
 Adenoma [MESH:D000236] (4051) 
 Adenoma, Liver Cell [MESH:D018248] (685)
 Mesothelioma [MESH:D008654] (2567)
 Carcinoma [MESH:D002277] (7263) 
 Carcinoma, Transitional Cell [MESH:D002295] (2662)
 Adenocarcinoma [MESH:D000230] (6565) 
 Carcinoma, Adenoid Cystic [MESH:D003528] (1561)
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Adenocarcinoma, Follicular [MESH:D018263] (677) 
 Thyroid cancer, follicular [MESH:C572845] (674)
 Carcinoma in Situ [MESH:D002278] (2111) 
 Prostatic Intraepithelial Neoplasia [MESH:D019048] (1565)
 Carcinoma, Squamous Cell [MESH:D002294] (4294) 
 Carcinoma, squamous cell of head and neck [MESH:C535575] (1543)
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Neoplasms, Basal Cell [MESH:D018295] (1707) 
 Pilomatrixoma [MESH:D018296] (252)
 Neoplasms, Mesothelial [MESH:D018301] (2569) 
 Mesothelioma [MESH:D008654] (2567)
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Astrocytoma [MESH:D001254] (2692) 
 Glioblastoma [MESH:D005909] (2554)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive, Peripheral [MESH:D018241] (1433) 
 Neuroblastoma [MESH:D009447] (1420)
 Neoplasms, Squamous Cell [MESH:D018307] (4457) 
 Papilloma [MESH:D010212] (2243)
 Carcinoma, Squamous Cell [MESH:D002294] (4294) 
 Carcinoma, squamous cell of head and neck [MESH:C535575] (1543)
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Neoplasms, Nerve Tissue [MESH:D009380] (5201) 
 Meningioma [MESH:D008579] (978) 
 Meningioma, familial [MESH:C537443] (195)
 Neuroectodermal Tumors [MESH:D017599] (5059) 
 Neoplasms, Neuroepithelial [MESH:D018302] (4487) 
 Glioma [MESH:D005910] (4261) 
 Medulloblastoma [MESH:D008527] (1282)
 Astrocytoma [MESH:D001254] (2692) 
 Glioblastoma [MESH:D005909] (2554)
 Neuroectodermal Tumors, Primitive [MESH:D018242] (2005) 
 Medulloblastoma [MESH:D008527] (1282)
 Neuroectodermal Tumors, Primitive, Peripheral [MESH:D018241] (1433) 
 Neuroblastoma [MESH:D009447] (1420)
 Neuroendocrine Tumors [MESH:D018358] (3625) 
 Melanoma [MESH:D008545] (3508)
 Neoplasms, Plasma Cell [MESH:D054219] (2772) 
 Multiple Myeloma [MESH:D009101] (2767)
 Neoplasms, Vascular Tissue [MESH:D009383] (2959) 
 Hemangioma [MESH:D006391] (690)
 Hemangiosarcoma [MESH:D006394] (1836)
 Meningioma [MESH:D008579] (978) 
 Meningioma, familial [MESH:C537443] (195)
 Nevi and Melanomas [MESH:D018326] (3572) 
 Melanoma [MESH:D008545] (3508)
 Neoplasms by Site [MESH:D009371] (9169) 
 Breast Neoplasms [MESH:D001943] (6077)
 Skin Neoplasms [MESH:D012878] (2992)
 Digestive System Neoplasms [MESH:D004067] (7487) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Gastrointestinal Neoplasms [MESH:D005770] (6452) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Esophageal Neoplasms [MESH:D004938] (3737) 
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Intestinal Neoplasms [MESH:D007414] (5358) 
 Cecal Neoplasms [MESH:D002430] (822)
 Colorectal Neoplasms [MESH:D015179] (5294) 
 Colonic Neoplasms [MESH:D003110] (4405)
 Liver Neoplasms [MESH:D008113] (6048) 
 Adenoma, Liver Cell [MESH:D018248] (685)
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Liver Neoplasms, Experimental [MESH:D008114] (2837)
 Endocrine Gland Neoplasms [MESH:D004701] (4925) 
 Ovarian Neoplasms [MESH:D010051] (3275)
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Head and Neck Neoplasms [MESH:D006258] (4612) 
 Carcinoma, squamous cell of head and neck [MESH:C535575] (1543)
 Esophageal Neoplasms [MESH:D004938] (3737) 
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Mouth Neoplasms [MESH:D009062] (2263) 
 Salivary Gland Neoplasms [MESH:D012468] (968)
 Mammary Neoplasms, Animal [MESH:D015674] (3404) 
 Mammary Neoplasms, Experimental [MESH:D008325] (3268)
 Nervous System Neoplasms [MESH:D009423] (3130) 
 Central Nervous System Neoplasms [MESH:D016543] (3055) 
 Brain Neoplasms [MESH:D001932] (2764)
 Meningeal Neoplasms [MESH:D008577] (984) 
 Meningioma [MESH:D008579] (978) 
 Meningioma, familial [MESH:C537443] (195)
 Thoracic Neoplasms [MESH:D013899] (6032) 
 Respiratory Tract Neoplasms [MESH:D012142] (6020) 
 Lung Neoplasms [MESH:D008175] (6015) 
 Bronchial Neoplasms [MESH:D001984] (3608) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
 Small Cell Lung Carcinoma [MESH:D055752] (1380)
 Urogenital Neoplasms [MESH:D014565] (7002) 
 Genital Neoplasms, Female [MESH:D005833] (2540) 
 Uterine Neoplasms [MESH:D014594] (2431) 
 Endometrial Neoplasms [MESH:D016889] (1987)
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Wilms Tumor [MESH:D009396] (553)
 Neoplasms, Experimental [MESH:D009374] (5218) 
 Liver Neoplasms, Experimental [MESH:D008114] (2837)
 Mammary Neoplasms, Experimental [MESH:D008325] (3268)
 Tumor Virus Infections [MESH:D014412] (697) 
 Epstein-Barr Virus Infections [MESH:D020031] (693) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Neoplasms, Multiple Primary [MESH:D009378] (961) 
 Hamartoma Syndrome, Multiple [MESH:D006223] (262) 
 Proteus Syndrome [MESH:D016715] (152)
 Neoplastic Processes [MESH:D009385] (5317) 
 Neoplasm Invasiveness [MESH:D009361] (3388)
 Neoplasm Metastasis [MESH:D009362] (4441)
 Carcinogenesis [MESH:D063646] (3391) 
 Cell Transformation, Neoplastic [MESH:D002471] (3389)
 Neoplastic Syndromes, Hereditary [MESH:D009386] (2578) 
 Meningioma, familial [MESH:C537443] (195)
 Juvenile polyposis syndrome [MESH:C537702] (196)
 Hamartoma Syndrome, Multiple [MESH:D006223] (260)
 Wilms Tumor [MESH:D009396] (553)
 Precancerous Conditions [MESH:D011230] (2858) 
 Aberrant Crypt Foci [MESH:D058739] (326)
 Pregnancy Complications, Neoplastic [MESH:D011252] (71) 
 Trophoblastic Neoplasms [MESH:D014328] (67) 
 Gestational Trophoblastic Disease [MESH:D031901] (65)
 Tumor Virus Infections [MESH:D014412] (759) 
 Epstein-Barr Virus Infections [MESH:D020031] (693) 
 Burkitt Lymphoma [MESH:D002051] (691)
C05. Musculoskeletal Diseases 
C05. Musculoskeletal Diseases
 Musculoskeletal Diseases [MESH:D009140] (8705) 
 Bone Diseases [MESH:D001847] (5801) 
 Bone Diseases, Developmental [MESH:D001848] (3315) 
 Proteus Syndrome [MESH:D016715] (152)
 Bone Diseases, Metabolic [MESH:D001851] (3492) 
 Osteoporosis [MESH:D010024] (3037) 
 Osteoporosis, Postmenopausal [MESH:D015663] (2351)
 Joint Diseases [MESH:D007592] (4657) 
 Arthritis [MESH:D001168] (4416) 
 Arthritis, Experimental [MESH:D001169] (3142)
 Arthritis, Rheumatoid [MESH:D001172] (3603)
 Musculoskeletal Abnormalities [MESH:D009139] (3796) 
 Craniofacial Abnormalities [MESH:D019465] (3098) 
 LEOPARD Syndrome [MESH:D044542] (299)
 Macrocephaly [MESH:D058627] (264) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
 Limb Deformities, Congenital [MESH:D017880] (1813) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Polydactyly [MESH:D017689] (318)
 Proteus Syndrome [MESH:D016715] (152)
 Rheumatic Diseases [MESH:D012216] (4032) 
 Arthritis, Rheumatoid [MESH:D001172] (3603)
C06. Digestive System Diseases 
C06. Digestive System Diseases
 Digestive System Diseases [MESH:D004066] (9461) 
 Biliary Tract Diseases [MESH:D001660] (3845) 
 Bile Duct Diseases [MESH:D001649] (3512) 
 Cholestasis [MESH:D002779] (3419) 
 Cholestasis, Intrahepatic [MESH:D002780] (1510) 
 Liver Cirrhosis, Biliary [MESH:D008105] (1274)
 Digestive System Abnormalities [MESH:D004065] (2127) 
 Esophageal Atresia [MESH:D004933] (47) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Digestive System Neoplasms [MESH:D004067] (7493) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Gastrointestinal Neoplasms [MESH:D005770] (6460) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Esophageal Neoplasms [MESH:D004938] (3737) 
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Cecal Neoplasms [MESH:D002430] (822)
 Colorectal Neoplasms [MESH:D015179] (5294) 
 Colonic Neoplasms [MESH:D003110] (4405)
 Liver Neoplasms [MESH:D008113] (6048) 
 Adenoma, Liver Cell [MESH:D018248] (685)
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Liver Neoplasms, Experimental [MESH:D008114] (2837)
 Gastrointestinal Diseases [MESH:D005767] (7443) 
 Esophageal Diseases [MESH:D004935] (4255) 
 Esophageal Atresia [MESH:D004933] (47) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Esophageal Neoplasms [MESH:D004938] (3737) 
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Gastrointestinal Neoplasms [MESH:D005770] (6460) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Esophageal Neoplasms [MESH:D004938] (3737) 
 Esophageal Squamous Cell Carcinoma [MESH:C562729] (2396)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Cecal Neoplasms [MESH:D002430] (822)
 Colorectal Neoplasms [MESH:D015179] (5294) 
 Colonic Neoplasms [MESH:D003110] (4405)
 Intestinal Diseases [MESH:D007410] (6206) 
 Cecal Diseases [MESH:D002429] (1330) 
 Cecal Neoplasms [MESH:D002430] (822)
 Colonic Diseases [MESH:D003108] (5564) 
 Colorectal Neoplasms [MESH:D015179] (5282) 
 Colonic Neoplasms [MESH:D003110] (4405)
 Intestinal Neoplasms [MESH:D007414] (5359) 
 Cecal Neoplasms [MESH:D002430] (822)
 Colorectal Neoplasms [MESH:D015179] (5294) 
 Colonic Neoplasms [MESH:D003110] (4405)
 Intestinal Polyposis [MESH:D044483] (1610) 
 Juvenile polyposis syndrome [MESH:C537702] (196)
 Rectal Diseases [MESH:D012002] (4596) 
 Colorectal Neoplasms [MESH:D015179] (4534)
 Peptic Ulcer [MESH:D010437] (3172) 
 Stomach Ulcer [MESH:D013276] (2915)
 Stomach Diseases [MESH:D013272] (5325) 
 Stomach Neoplasms [MESH:D013274] (4942)
 Peptic Ulcer [MESH:D010437] (2994) 
 Stomach Ulcer [MESH:D013276] (2915)
 Liver Diseases [MESH:D008107] (8167) 
 Drug-Induced Liver Injury [MESH:D056486] (4936)
 Fatty Liver [MESH:D005234] (3584)
 Hepatitis [MESH:D006505] (3883)
 Cholestasis, Intrahepatic [MESH:D002780] (1510) 
 Liver Cirrhosis, Biliary [MESH:D008105] (1274)
 Liver Cirrhosis [MESH:D008103] (5542) 
 Liver Cirrhosis, Alcoholic [MESH:D008104] (3066)
 Liver Cirrhosis, Biliary [MESH:D008105] (1274)
 Liver Diseases, Alcoholic [MESH:D008108] (3243) 
 Liver Cirrhosis, Alcoholic [MESH:D008104] (3066)
 Liver Neoplasms [MESH:D008113] (6048) 
 Adenoma, Liver Cell [MESH:D018248] (685)
 Carcinoma, Hepatocellular [MESH:D006528] (5375)
 Liver Neoplasms, Experimental [MESH:D008114] (2837)
 Pancreatic Diseases [MESH:D010182] (4453) 
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Peritoneal Diseases [MESH:D010532] (1119) 
 Peritonitis [MESH:D010538] (800)
C07. Stomatognathic Diseases 
C07. Stomatognathic Diseases
 Stomatognathic Diseases [MESH:D009057] (5348) 
 Mouth Diseases [MESH:D009059] (4783) 
 Behcet Syndrome [MESH:D001528] (1784)
 Mouth Neoplasms [MESH:D009062] (2263) 
 Salivary Gland Neoplasms [MESH:D012468] (968)
 Salivary Gland Diseases [MESH:D012466] (1213) 
 Salivary Gland Neoplasms [MESH:D012468] (968)
C08. Respiratory Tract Diseases 
C08. Respiratory Tract Diseases
 Respiratory Tract Diseases [MESH:D012140] (7881) 
 Bronchial Diseases [MESH:D001982] (4382) 
 Asthma [MESH:D001249] (4098)
 Lung Diseases [MESH:D008171] (7249) 
 Pulmonary Edema [MESH:D011654] (2109)
 Pulmonary Embolism [MESH:D011655] (1118)
 Lung Diseases, Obstructive [MESH:D008173] (4697) 
 Asthma [MESH:D001249] (3903)
 Lung Injury [MESH:D055370] (3688) 
 Acute Lung Injury [MESH:D055371] (1907)
 Lung Neoplasms [MESH:D008175] (6012) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
 Small Cell Lung Carcinoma [MESH:D055752] (1380)
 Respiratory Hypersensitivity [MESH:D012130] (4401) 
 Asthma [MESH:D001249] (4098)
 Respiratory Tract Neoplasms [MESH:D012142] (6053) 
 Lung Neoplasms [MESH:D008175] (6013) 
 Bronchial Neoplasms [MESH:D001984] (3608) 
 Carcinoma, Bronchogenic [MESH:D002283] (3606) 
 Carcinoma, Non-Small-Cell Lung [MESH:D002289] (3540)
 Small Cell Lung Carcinoma [MESH:D055752] (1380)
C10. Nervous System Diseases 
C10. Nervous System Diseases
 Z. Exceptions (4027) 
 Not Fully Specified [NFS] (4027)
 Nervous System Diseases [MESH:D009422] (13325) 
 Central Nervous System Diseases [MESH:D002493] (9745) 
 Brain Diseases [MESH:D001927] (9294) 
 Brain Neoplasms [MESH:D001932] (2764)
 Cerebrovascular Disorders [MESH:D002561] (5542) 
 Brain Ischemia [MESH:D002545] (4873) 
 Brain Infarction [MESH:D020520] (2571) 
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Arterial Diseases [MESH:D020765] (2463) 
 Cerebral Arterial Diseases [MESH:D002539] (2440) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Stroke [MESH:D020521] (3702) 
 Brain Infarction [MESH:D020520] (2571) 
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Dementia [MESH:D003704] (4498) 
 Alzheimer Disease [MESH:D000544] (4275)
 Epilepsy [MESH:D004827] (6274) 
 Seizures [MESH:D012640] (4502)
 Status Epilepticus [MESH:D013226] (4014)
 Epilepsy, Generalized [MESH:D004829] (1431) 
 Epilepsy, Tonic-Clonic [MESH:D004830] (1042)
 Hydrocephalus [MESH:D006849] (276) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Intracranial Hypertension [MESH:D019586] (368) 
 Hydrocephalus [MESH:D006849] (274) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Movement Disorders [MESH:D009069] (4823) 
 Dyskinesias [MESH:D020820] (1827) 
 Dyskinesia, Drug-Induced [MESH:D004409] (1389)
 Nervous System Malformations [MESH:D009421] (3354) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Malformations of Cortical Development [MESH:D054220] (1406) 
 Macrocephaly [MESH:D058627] (264) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
 Nervous System Neoplasms [MESH:D009423] (3073) 
 Central Nervous System Neoplasms [MESH:D016543] (3055) 
 Brain Neoplasms [MESH:D001932] (2764)
 Meningeal Neoplasms [MESH:D008577] (984) 
 Meningioma [MESH:D008579] (978) 
 Meningioma, familial [MESH:C537443] (195)
 Neurocutaneous Syndromes [MESH:D020752] (1230) 
 von Hippel-Lindau Disease [MESH:D006623] (580)
 Neurodegenerative Diseases [MESH:D019636] (6613) 
 Tauopathies [MESH:D024801] (4289) 
 Alzheimer Disease [MESH:D000544] (4275)
 Neurologic Manifestations [MESH:D009461] (8964) 
 Seizures [MESH:D012640] (4514)
 Neurobehavioral Manifestations [MESH:D019954] (5230) 
 Intellectual Disability [MESH:D008607] (3054)
 Communication Disorders [MESH:D003147] (2918) 
 Language Disorders [MESH:D007806] (653) 
 Language Development Disorders [MESH:D007805] (351)
 Neuromuscular Manifestations [MESH:D020879] (2130) 
 Muscular Atrophy [MESH:D009133] (1234)
 Neuromuscular Diseases [MESH:D009468] (7336) 
 Peripheral Nervous System Diseases [MESH:D010523] (6151) 
 Diabetic Neuropathies [MESH:D003929] (2442)
 Neurotoxicity Syndromes [MESH:D020258] (4570) 
 Dyskinesia, Drug-Induced [MESH:D004409] (1389)
C11. Eye Diseases 
C11. Eye Diseases
 Eye Diseases [MESH:D005128] (6245) 
 Corneal Diseases [MESH:D003316] (1445) 
 Corneal Dystrophies, Hereditary [MESH:D003317] (341) 
 Macular Dystrophy, Retinal, 2 [MESH:C562746] (63)
 Eye Abnormalities [MESH:D005124] (1233) 
 Anophthalmos [MESH:D000853] (63)
 Microphthalmos [MESH:D008850] (273) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Eye Diseases, Hereditary [MESH:D015785] (1869) 
 Corneal Dystrophies, Hereditary [MESH:D003317] (341) 
 Macular Dystrophy, Retinal, 2 [MESH:C562746] (63)
 Retinitis Pigmentosa [MESH:D012174] (414) 
 Cone-Rod Dystrophy 12 [MESH:C567206] (63)
 Retinitis Pigmentosa 41 [MESH:C567422] (63)
 Refractive Errors [MESH:D012030] (457) 
 Anisometropia [MESH:D015858] (152)
 Retinal Diseases [MESH:D012164] (3747) 
 Retinal Degeneration [MESH:D012162] (2386) 
 Macular Degeneration [MESH:D008268] (995) 
 Stargardt disease 4 [MESH:C535521] (63)
 Retinal Dystrophies [MESH:D058499] (1315) 
 Retinitis Pigmentosa [MESH:D012174] (1307) 
 Cone-Rod Dystrophy 12 [MESH:C567206] (63)
 Retinitis Pigmentosa 41 [MESH:C567422] (63)
 Uveal Diseases [MESH:D014603] (2428) 
 Uveitis [MESH:D014605] (2157) 
 Panuveitis [MESH:D015864] (1805) 
 Uveitis, Anterior [MESH:D014606] (1791) 
 Behcet Syndrome [MESH:D001528] (1784)
C12. Male Urogenital Diseases 
C12. Male Urogenital Diseases
 Male Urogenital Diseases [MESH:D052801] (8891) 
 Genital Diseases, Male [MESH:D005832] (6794) 
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Prostatic Diseases [MESH:D011469] (6204) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urogenital Neoplasms [MESH:D014565] (6932) 
 Genital Neoplasms, Male [MESH:D005834] (6224) 
 Prostatic Neoplasms [MESH:D011471] (6135)
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Wilms Tumor [MESH:D009396] (553)
 Urologic Diseases [MESH:D014570] (7792) 
 Kidney Diseases [MESH:D007674] (7242) 
 Nephrosis [MESH:D009401] (2228)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Wilms Tumor [MESH:D009396] (553)
 Nephritis [MESH:D009393] (4236) 
 Glomerulonephritis [MESH:D005921] (3758) 
 Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)
 Renal Insufficiency [MESH:D051437] (4951) 
 Renal Insufficiency, Chronic [MESH:D051436] (2931) 
 Kidney Failure, Chronic [MESH:D007676] (2930)
 Urinary Bladder Diseases [MESH:D001745] (4374) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
C13. Female Urogenital Diseases and Pregnancy Complications 
C13. Female Urogenital Diseases and Pregnancy Complications
 Female Urogenital Diseases [MESH:D052776] (8724) 
 Genital Diseases, Female [MESH:D005831] (5563) 
 Adnexal Diseases [MESH:D000291] (4273) 
 Ovarian Diseases [MESH:D010049] (4255) 
 Ovarian Neoplasms [MESH:D010051] (3281)
 Uterine Diseases [MESH:D014591] (2479) 
 Endometrial Hyperplasia [MESH:D004714] (263)
 Uterine Neoplasms [MESH:D014594] (2430) 
 Endometrial Neoplasms [MESH:D016889] (1984)
 Urogenital Neoplasms [MESH:D014565] (5792) 
 Genital Neoplasms, Female [MESH:D005833] (3810) 
 Ovarian Neoplasms [MESH:D010051] (3281)
 Uterine Neoplasms [MESH:D014594] (2433) 
 Endometrial Neoplasms [MESH:D016889] (1989)
 Urologic Neoplasms [MESH:D014571] (5315) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Wilms Tumor [MESH:D009396] (553)
 Urologic Diseases [MESH:D014570] (7793) 
 Kidney Diseases [MESH:D007674] (7242) 
 Nephrosis [MESH:D009401] (2228)
 Kidney Neoplasms [MESH:D007680] (3966) 
 Wilms Tumor [MESH:D009396] (553)
 Nephritis [MESH:D009393] (4236) 
 Glomerulonephritis [MESH:D005921] (3758) 
 Glomerulosclerosis, Focal Segmental [MESH:D005923] (1754)
 Renal Insufficiency [MESH:D051437] (4951) 
 Renal Insufficiency, Chronic [MESH:D051436] (2931) 
 Kidney Failure, Chronic [MESH:D007676] (2930)
 Urinary Bladder Diseases [MESH:D001745] (4375) 
 Urinary Bladder Neoplasms [MESH:D001749] (4079)
 Pregnancy Complications [MESH:D011248] (4768) 
 Pregnancy Complications, Neoplastic [MESH:D011252] (71) 
 Trophoblastic Neoplasms [MESH:D014328] (67) 
 Gestational Trophoblastic Disease [MESH:D031901] (65)
C14. Cardiovascular Diseases 
C14. Cardiovascular Diseases
 Cardiovascular Diseases [MESH:D002318] (10123) 
 Cardiovascular Abnormalities [MESH:D018376] (3153) 
 Heart Defects, Congenital [MESH:D006330] (2447) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 LEOPARD Syndrome [MESH:D044542] (299)
 Heart Diseases [MESH:D006331] (8614) 
 Heart Failure [MESH:D006333] (4058)
 Arrhythmias, Cardiac [MESH:D001145] (4679) 
 Long QT Syndrome [MESH:D008133] (693)
 Cardiomegaly [MESH:D006332] (4081) 
 Hypertrophy, Left Ventricular [MESH:D017379] (1430)
 Cardiomyopathies [MESH:D009202] (5331) 
 Cardiomyopathy, Hypertrophic [MESH:D002312] (1516)
 Myocardial Reperfusion Injury [MESH:D015428] (3500)
 Heart Defects, Congenital [MESH:D006330] (2443) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 LEOPARD Syndrome [MESH:D044542] (299)
 Heart Valve Diseases [MESH:D006349] (3333) 
 Aortic Valve Stenosis [MESH:D001024] (1742) 
 Aortic Stenosis, Subvalvular [MESH:D001020] (1455) 
 Cardiomyopathy, Hypertrophic [MESH:D002312] (1451)
 Pulmonary Valve Stenosis [MESH:D011666] (360) 
 LEOPARD Syndrome [MESH:D044542] (299)
 Myocardial Ischemia [MESH:D017202] (5787) 
 Myocardial Infarction [MESH:D009203] (4122)
 Myocardial Reperfusion Injury [MESH:D015428] (3500)
 Vascular Diseases [MESH:D014652] (8691) 
 Hyperemia [MESH:D006940] (2372)
 Hypertension [MESH:D006973] (5655)
 Hypotension [MESH:D007022] (4045)
 Angiomatosis [MESH:D000798] (620) 
 von Hippel-Lindau Disease [MESH:D006623] (580)
 Cerebrovascular Disorders [MESH:D002561] (5541) 
 Brain Ischemia [MESH:D002545] (4873) 
 Brain Infarction [MESH:D020520] (2571) 
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Intracranial Arterial Diseases [MESH:D020765] (2468) 
 Cerebral Arterial Diseases [MESH:D002539] (2440) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Stroke [MESH:D020521] (3702) 
 Brain Infarction [MESH:D020520] (2571) 
 Cerebral Infarction [MESH:D002544] (2458) 
 Infarction, Middle Cerebral Artery [MESH:D020244] (2268)
 Embolism and Thrombosis [MESH:D016769] (3374) 
 Embolism [MESH:D004617] (1137) 
 Pulmonary Embolism [MESH:D011655] (1118)
 Hemostatic Disorders [MESH:D020141] (2894) 
 Multiple Myeloma [MESH:D009101] (2765)
 Myocardial Ischemia [MESH:D017202] (5791) 
 Myocardial Reperfusion Injury [MESH:D015428] (3500)
 Myocardial Infarction [MESH:D009203] (4151) 
 No-Reflow Phenomenon [MESH:D054318] (277)
 Reperfusion Injury [MESH:D015427] (4968) 
 Myocardial Reperfusion Injury [MESH:D015428] (3500)
 Vasculitis [MESH:D014657] (2604) 
 Behcet Syndrome [MESH:D001528] (1784)
C15. Hemic and Lymphatic Diseases 
C15. Hemic and Lymphatic Diseases
 Hematologic Diseases [MESH:D006402] (6174) 
 Blood Platelet Disorders [MESH:D001791] (3174) 
 Thrombocytopenia [MESH:D013921] (2966)
 Blood Protein Disorders [MESH:D001796] (3051) 
 Paraproteinemias [MESH:D010265] (2781) 
 Multiple Myeloma [MESH:D009101] (2765)
 Bone Marrow Diseases [MESH:D001855] (2944) 
 Myelodysplastic Syndromes [MESH:D009190] (2093)
 Hemorrhagic Disorders [MESH:D006474] (3359) 
 Hemostatic Disorders [MESH:D020141] (2932) 
 Multiple Myeloma [MESH:D009101] (2765)
 Lymphatic Diseases [MESH:D008206] (5167) 
 Lymphoproliferative Disorders [MESH:D008232] (4638) 
 Leukemia, Lymphoid [MESH:D007945] (3047) 
 Leukemia, B-Cell [MESH:D015448] (2564) 
 Leukemia, Lymphocytic, Chronic, B-Cell [MESH:D015451] (2562)
 Precursor Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054198] (1754) 
 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054218] (510)
 Lymphoma [MESH:D008223] (3684) 
 Lymphoma, Non-Hodgkin [MESH:D008228] (3330) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Mantle-Cell [MESH:D020522] (561)
 Lymphoma, B-Cell [MESH:D016393] (2624) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Large B-Cell, Diffuse [MESH:D016403] (2012)
C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities 
C16. Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities [MESH:D009358] (12152) 
 Congenital Abnormalities [MESH:D000013] (8109) 
 Abnormalities, Drug-Induced [MESH:D000014] (1024)
 Abnormalities, Multiple [MESH:D000015] (3192) 
 LEOPARD Syndrome [MESH:D044542] (299)
 Proteus Syndrome [MESH:D016715] (152)
 Cardiovascular Abnormalities [MESH:D018376] (3294) 
 Heart Defects, Congenital [MESH:D006330] (2611) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 LEOPARD Syndrome [MESH:D044542] (299)
 Long QT Syndrome [MESH:D008133] (693)
 Digestive System Abnormalities [MESH:D004065] (507) 
 Esophageal Atresia [MESH:D004933] (47) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Eye Abnormalities [MESH:D005124] (1233) 
 Anophthalmos [MESH:D000853] (63)
 Microphthalmos [MESH:D008850] (273) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Musculoskeletal Abnormalities [MESH:D009139] (3779) 
 Craniofacial Abnormalities [MESH:D019465] (3064) 
 LEOPARD Syndrome [MESH:D044542] (299)
 Macrocephaly [MESH:D058627] (264) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
 Limb Deformities, Congenital [MESH:D017880] (1813) 
 VACTERL hydrocephaly [MESH:C536521] (151)
 Polydactyly [MESH:D017689] (318)
 Proteus Syndrome [MESH:D016715] (152)
 Nervous System Malformations [MESH:D009421] (3354) 
 Microphthalmia, Syndromic 3 [MESH:C565948] (43)
 Malformations of Cortical Development [MESH:D054220] (1406) 
 Macrocephaly [MESH:D058627] (264) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
 Genetic Diseases, Inborn [MESH:D030342] (9766) 
 Eye Diseases, Hereditary [MESH:D015785] (1867) 
 Corneal Dystrophies, Hereditary [MESH:D003317] (341) 
 Macular Dystrophy, Retinal, 2 [MESH:C562746] (63)
 Retinitis Pigmentosa [MESH:D012174] (442) 
 Cone-Rod Dystrophy 12 [MESH:C567206] (63)
 Retinitis Pigmentosa 41 [MESH:C567422] (63)
 Metabolism, Inborn Errors [MESH:D008661] (6032) 
 Xanthinuria, Type I [MESH:C562584] (190)
 Peroxisomal Disorders [MESH:D018901] (1788) 
 Acatalasia [MESH:D020642] (788)
 Neoplastic Syndromes, Hereditary [MESH:D009386] (2578) 
 Meningioma, familial [MESH:C537443] (195)
 Juvenile polyposis syndrome [MESH:C537702] (196)
 Hamartoma Syndrome, Multiple [MESH:D006223] (260)
 Wilms Tumor [MESH:D009396] (553)
 Infant, Newborn, Diseases [MESH:D007232] (3064) 
 Asphyxia Neonatorum [MESH:D001238] (1648)
C17. Skin and Connective Tissue Diseases 
C17. Skin and Connective Tissue Diseases
 Connective Tissue Diseases [MESH:D003240] (4490) 
 Rheumatic Diseases [MESH:D012216] (3619) 
 Arthritis, Rheumatoid [MESH:D001172] (3603)
 Skin Diseases [MESH:D012871] (8774) 
 Keratosis [MESH:D007642] (1941)
 Lipomatosis [MESH:D008068] (182)
 Skin Neoplasms [MESH:D012878] (2991)
 Breast Diseases [MESH:D001941] (6148) 
 Breast Neoplasms [MESH:D001943] (6077)
 Pigmentation Disorders [MESH:D010859] (1215) 
 Hyperpigmentation [MESH:D017495] (523) 
 Melanosis [MESH:D008548] (459) 
 Lentigo [MESH:D007911] (329) 
 LEOPARD Syndrome [MESH:D044542] (299)
 Skin Diseases, Papulosquamous [MESH:D017444] (3392) 
 Psoriasis [MESH:D011565] (3278)
 Skin Diseases, Vascular [MESH:D017445] (3288) 
 Behcet Syndrome [MESH:D001528] (1784)
C18. Nutritional and Metabolic Diseases 
C18. Nutritional and Metabolic Diseases
 Metabolic Diseases [MESH:D008659] (9025) 
 Glucose Metabolism Disorders [MESH:D044882] (6122) 
 Diabetes Mellitus [MESH:D003920] (5891) 
 Diabetes Mellitus, Experimental [MESH:D003921] (4771)
 Diabetes Mellitus, Type 1 [MESH:D003922] (1897)
 Diabetes Mellitus, Type 2 [MESH:D003924] (4219)
 Hyperinsulinism [MESH:D006946] (3586) 
 Insulin Resistance [MESH:D007333] (3511)
 Lipid Metabolism Disorders [MESH:D052439] (3225) 
 Lipomatosis [MESH:D008068] (182)
 Dyslipidemias [MESH:D050171] (2428) 
 Hyperlipidemias [MESH:D006949] (1908) 
 Hypercholesterolemia [MESH:D006937] (1404)
 Metabolism, Inborn Errors [MESH:D008661] (6028) 
 Xanthinuria, Type I [MESH:C562584] (190)
 Peroxisomal Disorders [MESH:D018901] (1788) 
 Acatalasia [MESH:D020642] (788)
 Nutrition Disorders [MESH:D009748] (4945) 
 Malnutrition [MESH:D044342] (2754) 
 Deficiency Diseases [MESH:D003677] (2742) 
 Protein Deficiency [MESH:D011488] (1057)
C19. Endocrine System Diseases 
C19. Endocrine System Diseases
 Endocrine System Diseases [MESH:D004700] (8062) 
 Diabetes Mellitus [MESH:D003920] (6159) 
 Diabetes Mellitus, Experimental [MESH:D003921] (4771)
 Diabetes Mellitus, Type 1 [MESH:D003922] (1897)
 Diabetes Mellitus, Type 2 [MESH:D003924] (4219)
 Diabetes Complications [MESH:D048909] (4129) 
 Diabetic Neuropathies [MESH:D003929] (2443)
 Endocrine Gland Neoplasms [MESH:D004701] (4925) 
 Ovarian Neoplasms [MESH:D010051] (3275)
 Pancreatic Neoplasms [MESH:D010190] (3820)
 Gonadal Disorders [MESH:D006058] (5088) 
 Ovarian Diseases [MESH:D010049] (4253) 
 Ovarian Neoplasms [MESH:D010051] (3281)
 Parathyroid Diseases [MESH:D010279] (1604) 
 Hyperparathyroidism [MESH:D006961] (1475)
C20. Immune System Diseases 
C20. Immune System Diseases
 Immune System Diseases [MESH:D007154] (7674) 
 Autoimmune Diseases [MESH:D001327] (5067) 
 Arthritis, Rheumatoid [MESH:D001172] (3601)
 Diabetes Mellitus, Type 1 [MESH:D003922] (1893)
 Hypersensitivity [MESH:D006967] (5873) 
 Hypersensitivity, Immediate [MESH:D006969] (4980) 
 Respiratory Hypersensitivity [MESH:D012130] (4250) 
 Asthma [MESH:D001249] (3914)
 Immunoproliferative Disorders [MESH:D007160] (4761) 
 Lymphoproliferative Disorders [MESH:D008232] (4734) 
 Multiple Myeloma [MESH:D009101] (2767)
 Leukemia, Lymphoid [MESH:D007945] (3047) 
 Leukemia, B-Cell [MESH:D015448] (2564) 
 Leukemia, Lymphocytic, Chronic, B-Cell [MESH:D015451] (2562)
 Precursor Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054198] (1754) 
 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma [MESH:D054218] (510)
 Lymphoma [MESH:D008223] (3684) 
 Lymphoma, Non-Hodgkin [MESH:D008228] (3330) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Mantle-Cell [MESH:D020522] (561)
 Lymphoma, B-Cell [MESH:D016393] (2624) 
 Burkitt Lymphoma [MESH:D002051] (691)
 Lymphoma, Large B-Cell, Diffuse [MESH:D016403] (2012)
 Paraproteinemias [MESH:D010265] (2791) 
 Multiple Myeloma [MESH:D009101] (2765)
C22. Animal Diseases 
C22. Animal Diseases
 Animal Diseases [MESH:D000820] (3656) 
 Mammary Neoplasms, Animal [MESH:D015674] (2735)
C23. Pathological Conditions, Signs and Symptoms 
C23. Pathological Conditions, Signs and Symptoms
 Pathological Conditions, Anatomical [MESH:D020763] (6074) 
 Atrophy [MESH:D001284] (2603) 
 Muscular Atrophy [MESH:D009133] (1234)
 Hypertrophy [MESH:D006984] (4476) 
 Cardiomegaly [MESH:D006332] (3802) 
 Hypertrophy, Left Ventricular [MESH:D017379] (1430)
 Polyps [MESH:D011127] (1633) 
 Intestinal Polyps [MESH:D007417] (1592)
 Pathologic Processes [MESH:D010335] (9863) 
 Hyperplasia [MESH:D006965] (2463)
 Necrosis [MESH:D009336] (4019)
 Nerve Degeneration [MESH:D009410] (4061)
 Arrhythmias, Cardiac [MESH:D001145] (4658) 
 Long QT Syndrome [MESH:D008133] (691)
 Disease Attributes [MESH:D020969] (3654) 
 Disease Progression [MESH:D018450] (2868)
 Facies [MESH:D019066] (738) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
 Ischemia [MESH:D007511] (3049) 
 No-Reflow Phenomenon [MESH:D054318] (277)
 Neoplastic Processes [MESH:D009385] (5317) 
 Neoplasm Invasiveness [MESH:D009361] (3388)
 Neoplasm Metastasis [MESH:D009362] (4441)
 Carcinogenesis [MESH:D063646] (3391) 
 Cell Transformation, Neoplastic [MESH:D002471] (3389)
 Postoperative Complications [MESH:D011183] (5311) 
 Reperfusion Injury [MESH:D015427] (4968) 
 Myocardial Reperfusion Injury [MESH:D015428] (3500)
 Signs and Symptoms [MESH:D012816] (10659) 
 Edema [MESH:D004487] (3726)
 Neurologic Manifestations [MESH:D009461] (8702) 
 Seizures [MESH:D012640] (4502)
 Neurobehavioral Manifestations [MESH:D019954] (4706) 
 Intellectual Disability [MESH:D008607] (1476)
 Communication Disorders [MESH:D003147] (2918) 
 Language Disorders [MESH:D007806] (653) 
 Language Development Disorders [MESH:D007805] (351)
 Neuromuscular Manifestations [MESH:D020879] (2130) 
 Muscular Atrophy [MESH:D009133] (1234)
C25. Chemically-Induced Disorders 
C25. Chemically-Induced Disorders
 Drug-Related Side Effects and Adverse Reactions [MESH:D064420] (5839) 
 Drug-Induced Liver Injury [MESH:D056486] (4936)
 Dyskinesia, Drug-Induced [MESH:D004409] (1389)
 Poisoning [MESH:D011041] (6703) 
 Drug-Induced Liver Injury [MESH:D056486] (4936)
 Neurotoxicity Syndromes [MESH:D020258] (3323) 
 Dyskinesia, Drug-Induced [MESH:D004409] (1389)
 Substance-Related Disorders [MESH:D019966] (6308) 
 Amphetamine-Related Disorders [MESH:D019969] (2858)
 Alcohol-Related Disorders [MESH:D019973] (3869) 
 Alcohol-Induced Disorders [MESH:D020751] (3350) 
 Liver Diseases, Alcoholic [MESH:D008108] (3243) 
 Liver Cirrhosis, Alcoholic [MESH:D008104] (3066)
C26. Wounds and Injuries 
C26. Wounds and Injuries
 Z. Exceptions (2454) 
 Not Fully Specified [NFS] (2454)
 Wounds and Injuries [MESH:D014947] (5171) 
 Radiation Injuries [MESH:D011832] (2718) 
 Radiation Injuries, Experimental [MESH:D011833] (2662)
D02. Organic Chemicals 
D02. Organic Chemicals
 Organic Chemicals [MESH:D009930] (75987) 
 Hydrocarbons [MESH:D006838] (35762) 
 Terpenes [MESH:D013729] (10347) 
 Triterpenes [MESH:D014315] (3016) 
 Pentacyclic Triterpenes [MESH:D053978] (582)
E. Analytical, Diagnostic and Therapeutic Techniques and Equipment 
E. Analytical, Diagnostic and Therapeutic Techniques and Equipment
 Diagnosis [MESH:D003933] (1924) 
 Diagnostic Techniques and Procedures [MESH:D019937] (1902) 
 Physical Examination [MESH:D010808] (1041) 
 Facies [MESH:D019066] (704) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)
F. Psychiatry and Psychology 
F. Psychiatry and Psychology
 Mental Disorders [MESH:D001523] (2063) 
 Mental Disorders Diagnosed in Childhood [MESH:D019952] (1245) 
 Child Development Disorders, Pervasive [MESH:D002659] (157) 
 Autistic Disorder [MESH:D001321] (154) 
 Macrocephaly Autism Syndrome [MESH:C565342] (151)